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Sökning: onr:"swepub:oai:DiVA.org:hh-5660" > Effects of a Nordic...

Effects of a Nordic diet on cardiovascular and metabolic risk factors in hypercholesterolemic subjects: a randomized controlled study

Adamsson, Viola, (författare)
Enheten för Klinisk Nutrition och Metabolism. Institutionen för Folkhälso- och vårdvetenskap. Uppsala Universitet
Reumark, Anna, (författare)
MSc Kostvetenskap Lantmännen Food R&D, Stockholm
Fredriksson, Ing-Britt, (författare)
SSK Mitt Hjärta, Bollnäs
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Hammarström, Eskil, (författare)
SSK Mitt Hjärta, Bollnäs
Vessby, Bengt, (författare)
Enheten för Klinisk Nutrition och Metabolism. Institutionen för Folkhälso- och vårdvetenskap. Uppsala Universitet
Johansson, Gunnar, 1956- (författare)
Högskolan i Halmstad, Centrum för forskning om välfärd, hälsa och idrott (CVHI)
Riserus, Ulf, (författare)
Enheten för Klinisk Nutrition och Metabolism. Institutionen för Folkhälso- och vårdvetenskap. Uppsala Universitet
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Stockholm : Svenska Läkaresällskapet, 2009
Engelska.
  • Konferensbidrag (refereegranskat)
Abstract Ämnesord
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  • <p><strong>Background:</strong> Apart from lipid-lowering drugs, dietary changes can also reduce plasma LDL-C concentrations. No studies have been conducted to investigate the clinical effects of a diet with traditional foods originating from the Nordic countries. <strong>Method</strong>: In a randomised, controlled parallel-group intervention study 88 mildly hypercholesterolemic men and women were randomized to either an ad libitum Nordic diet (ND) or a control diet (CD) for 6 weeks. All meals and foods were provided to the participants in the ND group. Primary outcome measure was LDL-cholesterol, and secondary outcomes were blood pressure, plasma insulin and glucose concentrations. The ND was a high-fibre diet rich in plant foods (fruit, berries, vegetables, root vegetables, whole grain cereals and legumes), vegetable fats (rapeseed oil and nuts) and fatty fish, low-fat milk products, but low in salt, added sugars, saturated fats and red meats. <strong>Result:</strong> 86 subjects completed the study. Distribution of carbohydrates, fat and protein (E%) in ND was 54, 27, 19, respectively. ND lowered plasma total cholesterol 0.98±0.75 mmol/l (-16%), LDL-C by 0.83±0.67 mmol/l (-21%), HDL-C 0.08±0.23 mmol/l (-5%), including reduced LDL/HDL ratio by -0.42±0.57 (-14%) (all p&lt;0.01 versus controls). Insulin concentrations decreased by 0.51± 2.25 (-9%, p=0.01) and systolic blood pressure by 7±13 mmHg (-5%, P&lt;0.01) compared to controls. Despite diets were eaten ad libitum, body weight decreased by 3.0 kg in the ND (P&lt;0.001). No significant differences were found for diastolic blood pressure, triglycerides or plasma glucose. <strong>Conclusion:</strong> A Nordic diet improves blood lipid profile, and insulin sensitivity as well as lowering blood pressure to a clinically significant extent in hypercholesterolemic subjects.</p>

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  (hsv//swe)
MEDICAL AND HEALTH SCIENCES  (hsv//eng)

Nyckelord

MEDICINE
MEDICIN

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