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Cortical reorganiza...
Cortical reorganization following injury early in life
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Artzi, M. (författare)
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Shiran, S. I. (författare)
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Weinstein, M. (författare)
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Myers, V. (författare)
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Tarrasch, R. (författare)
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Schertz, M. (författare)
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Fattal-Valevski, A. (författare)
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Miller, E. (författare)
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Gordon, A. M. (författare)
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- Green, Dido (författare)
- Department Occupational Therapy, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Ben Bashat, D. (författare)
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(creator_code:org_t)
- Hindawi Publishing Corporation, 2016
- 2016
- Engelska.
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Ingår i: Neural Plasticity. - : Hindawi Publishing Corporation. - 2090-5904 .- 1687-5443.
- Relaterad länk:
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https://doi.org/10.1...
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https://hj.diva-port... (primary) (Raw object)
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http://downloads.hin...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The brain has a remarkable capacity for reorganization following injury, especially during the first years of life. Knowledge of structural reorganization and its consequences following perinatal injury is sparse. Here we studied changes in brain tissue volume, morphology, perfusion, and integrity in children with hemiplegia compared to typically developing children, using MRI. Children with hemiplegia demonstrated reduced total cerebral volume, with increased cerebrospinal fluid (CSF) and reduced total white matter volumes, with no differences in total gray matter volume, compared to typically developing children. An increase in cortical thickness at the hemisphere contralateral to the lesion (CLH) was detected in motor and language areas, which may reflect compensation for the gray matter loss in the lesion area or retention of ipsilateral pathways. In addition, reduced cortical thickness, perfusion, and surface area were detected in limbic areas. Increased CSF volume and precentral cortical thickness and reduced white matter volume were correlated with worse motor performance. Brain reorganization of the gray matter within the CLH, while not necessarily indicating better outcome, is suggested as a response to neuronal deficits following injury early in life.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- adolescent
- Article
- brain cortex lesion
- brain function
- brain injury
- brain perfusion
- brain size
- brain tissue
- cerebrospinal fluid
- child
- clinical article
- cortical thickness (brain)
- female
- gray matter
- hemiplegia
- human
- male
- morphology
- neuroimaging
- nuclear magnetic resonance imaging
- perinatal period
- white matter
- age
- brain cortex
- complication
- diagnostic imaging
- organ size
- pathophysiology
- physiology
- trends
- Age Factors
- Brain Injuries
- Cerebral Cortex
- Humans
- Magnetic Resonance Imaging
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Artzi, M.
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Shiran, S. I.
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Weinstein, M.
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Myers, V.
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Tarrasch, R.
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Schertz, M.
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visa fler...
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Fattal-Valevski, ...
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Miller, E.
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Gordon, A. M.
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Green, Dido
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Ben Bashat, D.
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Neurologi
- Artiklar i publikationen
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Neural Plasticit ...
- Av lärosätet
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Jönköping University