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Sökning: onr:"swepub:oai:DiVA.org:liu-43636" > Overexpression of I...

LIBRIS Formathandbok  (Information om MARC21)
00002911naa a22003493a 4500
008080901s2008 xx |||| |0|| 0|eng d
024a 744612 local
024a urn:nbn:se:liu:diva-436362 urn
040 a (SwePub)liu
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Zhao, Zeng-Ren,u Department of General Surgery Hebei Medical University, Shijiazhuang 050031, P.R. China4 aut0 (SwePub:)
2451 0a Overexpression of Id-1 protein is a marker in colorectal cancer progression
500 a Published
500 a 6
5208 enga <p>The inhibitor of differentiation/DNA binding 1 (Id-1), a negative regulator of basic helix-loop-helix transcription factors, plays an important role in the regulation of cell proliferation and differentiation. We examined the Id-1 expression by immunohistochemistry in 9 adenomas, 79 primary colorectal adenocarcinomas matched with 40 adjacent normal mucosa specimens and its relationship with clinicopathological factors. The Id-1 expression was increased in the carcinoma compared to the adjacent normal mucosa either in the unmatched and matched samples or to the adenoma. There was no significant difference in the Id-1 expression between normal mucosa and adenoma. The Id-1 expression of carcinoma was increased from Dukes' stages A to B, to C and to D. The cases with lymph node metastasis had a higher rate of a stronger Id-1 expression than those without lymph node metastasis. In conclusion, Id-1 overexpression plays an important role in colorectal cancer progression.</p>
650 7a MEDICIN OCH HÄLSOVETENSKAP2 hsv//swe0 (SwePub)3
650 7a MEDICAL AND HEALTH SCIENCES2 hsv//eng0 (SwePub)3
700a Zhang, Zhiyong,d 1970-,u Linköpings universitet, Hälsouniversitetet, Linköpings universitet, Onkologi4 aut0 (SwePub:liu)
700a Zhang, Hong,d 1957-,u Linköpings universitet, Hälsouniversitetet, Linköpings universitet, Dermatologi och venerologi4 aut0 (SwePub:liu)
700a Jiang, Li,u Department of Pathology Tangshan Gongren Hospital, Tangshan 063000, P.R. China4 aut0 (SwePub:)
700a Wang, Ming-Wei,u Laboratory Centre Hebei Medical University, Shijiazhuang 050031, P.R. China4 aut0 (SwePub:)
700a Sun, Xiao-Feng,d 1959-,u Linköpings universitet, Hälsouniversitetet, Linköpings universitet, Onkologi, Östergötlands Läns Landsting, Onkologiska kliniken US4 aut0 (SwePub:liu)
773t Oncology Reportsx 1021-335Xx 1791-2431g 19:2, s. 419-424q 19:2<419-424
8564 8u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18202790
8564 8u http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-43636y Till lärosätets (liu) databasx lärosäteslänk

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