Nationwide population-based study on 30-day mortality after radical prostatectomy in Sweden

Objective. The incidence of prostate cancer in Sweden is increasing rapidly, as is treatment with curative intent. Radical prostatectomy (RP) is currently commonly performed, either within or outside large high-volume centres. The aim of this study was to assess the 30-day mortality rate after RP in Sweden. Material and methods. In this nationwide population-based study, all men diagnosed with localized prostate cancer (andlt;= 70 years, clinical stadium T1-2, prostate-specific antigen andlt;20 ng/ml) who underwent RP in Sweden between 1997 and 2002 were identified through the National Prostate Cancer Register (NPCR). Mortality within 30 days of RP was analysed through linkage between the follow-up study of the NPCR and the Regional Population Registers. The cause of death in the death certificates were compared with data from the hospitals concerned. To validate the results, a record linkage between the Inpatient Register and the National Population Register was also performed. Results. The number of RPs performed increased over time. Among 3700 RPs performed, four deaths occurred during the first 30 days, yielding a 0.11% 30-day mortality rate. These deaths occurred at three different types of hospital and were all probably related to the RP. Conclusion. This study provides further evidence that RP is a procedure with very low perioperative mortality even when performed outside high-volume centres.

Adolfsson, Jan(SwePub:) (författare)
Bratt, Ola(SwePub:) (författare)
Johansson, Jan-Erik(SwePub:) (författare)
Ahlstrand, Christer(SwePub:) (författare)
Holmberg, Erik(SwePub:) (författare)
Stattin, Pär,Umeå universitet, Urologi och andrologi(SwePub:umu)past0003 (författare)
Hugosson, Jonas(SwePub:) (författare)
Umeå universitet.Medicinsk fakultet.Kirurgisk och perioperativ vetenskap.Urologi och andrologi.(SwePub:umu)799
Linköpings universitet.Institutionen för klinisk och experimentell medicin.Urologi.(SwePub:liu)2274
Linköpings universitet.Hälsouniversitetet.(SwePub:liu)1800
Östergötlands Läns Landsting.Kirurgi- och onkologicentrum.Urologiska kliniken i Östergötland.(SwePub:liu)4230
Lunds universitet.Medicin.Institutionen för kliniska vetenskaper, Lund.Sektion V.Urologi.(SwePub:lu)
Lund University.Faculty of Medicine.Department of Clinical Sciences, Lund.Division V.Department of Urology, Lund.(SwePub:lu)
Örebro universitet.Hälsoakademin.(SwePub:oru)445
Göteborgs universitet.Sahlgrenska akademin.Institutionen för kliniska vetenskaper, sektionen för onkologi, radiofysik, radiologi och urologi.(SwePub:scigloo)1617
University of Gothenburg.Sahlgrenska Academy.Institute of Clinical Sciences, Section for Oncology, Radiation Physics, Radiology and Urology.(SwePub:scigloo)1617