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Lack of control of hypertension in primary cardiovascular disease prevention in Europe : Results from the EURIKA study

Borghi, Claudio (författare)
Univ Bologna, Italy
Tubach, Florence (författare)
Hop Bichat Claude Bernard, France ; Univ Paris Diderot, France
De Backer, Guy (författare)
Univ Ghent, Belgium
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Dallongeville, Jean (författare)
Univ Lille Nord France, France
Guallar, Eliseo (författare)
Johns Hopkins Bloomberg Sch Publ Hlth, USA ; Natl Ctr Cardiovasc Res, Spain
Medina, Jesus (författare)
AstraZeneca, Spain
Perk, Joep (författare)
Linnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV)
Roy, Carine (författare)
Hop Bichat Claude Bernard, France
Banegas, Jose R. (författare)
Univ Autonoma Madrid IdiPaz, Spain ; CIBER Epidemiol & Publ Hlth CIBERESP, Spain
Rodriguez-Artalejo, Fernando (författare)
Univ Autonoma Madrid IdiPaz, Spain ; CIBER Epidemiol & Publ Hlth CIBERESP, Spain
Halcox, Julian P. (författare)
Swansea Univ, UK
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 (creator_code:org_t)
2016
2016
Engelska.
Ingår i: International Journal of Cardiology. - 0167-5273 .- 1874-1754. ; 218, s. 83-88
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Background: The prevalence of and factors associated with uncontrolled hypertension and apparent resistant hypertension were assessed in the European Study on Cardiovascular Risk Prevention and Management in Usual Daily Practice (EURIKA; NCT00882336). Methods: EURIKA was a cross-sectional observational study including patients being treated for the primary prevention of cardiovascular disease in 12 European countries. Patients were assessed if they were being treated for hypertension (N = 5220). Blood pressure control was defined according to European guidelines, with sensitivity analysis taking account of patients' age and diabetes status. Associated factors were assessed using multivariate analysis. Results: In the primary analysis, a total of 2691 patients (51.6%) had uncontrolled hypertension. Factors significantly associated with an increased risk of having uncontrolled hypertension included female sex (odds ratio [OR]: 2.29; 95% confidence interval [CI]: 1.93-2.73), body mass index (BMI; OR per kg/m(2): 1.03; 95% CI: 1.01-1.04), and geographic location. A total of 749 patients (14.3%) had apparent resistant hypertension. Factors significantly associated with an increased risk of having apparent resistant hypertension included BMI (OR per kg/m(2): 1.06; 95% CI: 1.04-1.08), diabetes (OR: 1.28; 95% CI: 1.06-1.53), use of statins (OR: 1.36; 95% CI: 1.15-1.62), serum uric acid levels (OR: 1.16; 95% CI: 1.09-1.23), and geographic location. Similar results were seen in sensitivity analyses. Conclusions: Over 50% of patients treated for hypertension continued to have uncontrolled blood pressure and 14.3% had apparent resistant hypertension. Positive associations were seen with other cardiovascular risk factors. (C) 2016 Elsevier Ireland Ltd. All rights reserved.

Ämnesord

MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nursing (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskaper -- Omvårdnad (hsv//swe)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences (hsv//eng)

Nyckelord

Hypertension
Cardiovascular disease
Observational study
Primary prevention
Risk factor
Hälsovetenskap
Health and Caring Sciences

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