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Neuroradiology can ...
Neuroradiology can predict the development of hand function in children with unilateral cerebral palsy
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- Holmefur, Marie, 1968- (författare)
- Örebro universitet,Institutionen för hälsovetenskap och medicin
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- Kits, Annika (författare)
- Karolinska Institutet
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- Bergström, Jakob (författare)
- Karolinska Institutet
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- Krumlinde-Sundholm, Lena (författare)
- Karolinska Institutet
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- Flodmark, Olof (författare)
- Karolinska Institutet
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- Forssberg, Hans (författare)
- Karolinska Institutet
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- Eliasson, Ann-Christin, 1950- (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2012-06-06
- 2013
- Engelska.
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Ingår i: Neurorehabilitation and Neural Repair. - : Sage Publications. - 1545-9683 .- 1552-6844. ; 27:1, s. 72-78
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Much variation is found in the development of hand function in children with unilateral cerebral palsy (CP).OBJECTIVE: To explore how anatomic brain abnormalities can be used to predict the development of hand function.METHODS: A total of 32 children with unilateral CP (16 boys and 16 girls) were evaluated at least once a year by the Assisting Hand Assessment (AHA). The data collection covered an age range from 18 months to 8 years (mean time in study, 4 years and 6 months). Computerized tomography or magnetic resonance imaging of the brain were assessed for patterns of brain damage, including the location of gray and extent of white-matter damage. The children were divided into groups according to lesion characteristics, and a series of univariate models were analyzed with a nonlinear mixed-effects model. The rate and maximum limit of development were calculated.RESULTS: The highest predictive power of better development of hand function was the absence of a concurrent lesion to the basal ganglia and thalamus, independent of the basic type of brain lesion. This model predicted both the rate of increasing ability and hand function at age 8 years. Hand function was also predicted by the basic pattern of damage and by the extent of white-matter damage. The presence of unilateral or bilateral damage had no predictive value.CONCLUSIONS: Neuroradiological findings can be used to make a crude prediction of the future development of the use of the affected hand in young children with unilateral CP.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsterapi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Therapy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Nyckelord
- cerebral palsy
- child development
- brain injuries
- magnetic resonance imaging
- motor skills
- rehabilitation
- predictive models
- Occupational therapy
- Arbetsterapi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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