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Sökning: onr:"swepub:oai:DiVA.org:oru-48970" > Obesity and renal c...

Obesity and renal cell cancer : a quantitative review

Bergström, A., (författare)
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Hsieh, C. C., (författare)
Cancer Center, UMass Medical School, Worcester, MA, USA; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Lindblad, Per, 1953- (författare)
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden; Department of Urology, Sundsvall Hospital, Sundsvall, Sweden
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Lu, C. M., (författare)
Cancer Center, UMass Medical School, Worcester, MA, USA; Department of Urology, Tian-Sheng Memorial Hospital, Pingtung, Taiwan
Cook, N. R., (författare)
Division of Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Wolk, A., (författare)
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
visa färre...
2001
Engelska.
Ingår i: British Journal of Cancer. - London, United Kingdom : Nature Publishing Group. - 0007-0920 .- 1532-1827. - 0007-0920 (Print) 0007-0920 (Linking) ; 85:7, s. 984-990
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • <p>Obesity has been associated with an increased risk of renal cell cancer among women, while the evidence for men is considered weaker. We conducted a quantitative summary analysis to evaluate the existing evidence that obesity increases the risk of renal cell cancer both among men and women. We identified all studies examining body weight in relation to kidney cancer, available in MEDLINE from 1966 to 1998. The quantitative summary analysis was limited to studies assessing obesity as body mass index (BMI, kg m(-2)), or equivalent. The risk estimates and the confidence intervals were extracted from the individual studies, and a mixed effect weighted regression model was used. We identified 22 unique studies on each sex, and the quantitative analysis included 14 studies on men and women, respectively. The summary relative risk estimate was 1.07 (95% CI 1.05-1.09) per unit of increase in BMI (corresponding to 3 kg body weight increase for a subject of average height). We found no evidence of effect modification by sex. Our quantitative summary shows that increased BMI is equally strongly associated with an increased risk of renal cell cancer among men and women.</p>

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Nyckelord

Adult
Aged
Body Mass Index
Carcinoma
Renal Cell/*etiology
Female
Humans
Kidney Neoplasms/*etiology
Male
Middle Aged
Obesity/*complications
Sex Factors

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Av författaren/redakt...
Bergström, A.
Hsieh, C. C.
Lindblad, Per, 1 ...
Lu, C. M.
Cook, N. R.
Wolk, A.
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MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
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