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International renal-cell cancer study. IV. Occupation

Mandel, J. S., (författare)
School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States
McLaughlin, J. K., (författare)
National Cancer Institute, Division of Cancer Etiology, Bethesda, Maryland, United States
Schlehofer, B., (författare)
German Cancer Research Center, Division of Epidemiology, Heidelberg, Germany
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Mellemgaard, A., (författare)
Danish Cancer Society, Copenhagen, Denmark
Helmert, U., (författare)
Bremer Institute for Prevention and Social Medicine, Bremen, Germany
Lindblad, Per, 1953- (författare)
Department of Cancer Epidemiology, University Hospital, Uppsala, Sweden
McCredie, M., (författare)
Cancer Epidemiology Research Unit, New South Wales Cancer Council, Sydney, Australia
Adami, H. O., (författare)
Uppsala University, Uppsala, Sweden
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1995
Engelska.
Ingår i: International Journal of Cancer. - New York, USA : John Wiley & Sons. - 0020-7136. - 0020-7136 (Print) 0020-7136 (Linking) ; 61:5, s. 601-605
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • The relationship between renal-cell cancer (RCC) and occupation was investigated in an international multicenter population-based case-control study. Study centers in Australia, Denmark, Germany, Sweden and the United States interviewed 1732 incident RCC cases and 2309 controls. Significant associations were found with employment in the blast-furnace or the coke-oven industry [relative risk (RR), 1.7; 95% confidence interval (CI), 1.1-2.7], the iron and steel industry (RR, 1.6; 95% CI, 1.2-2.2) and exposure to asbestos (RR, 1.4; 95% CI, 1.1-1.8), cadmium (RR, 2.0; 95% CI, 1.0-3.9), dry-cleaning solvents (RR, 1.4; 95% CI, 1.1-1.7), gasoline (RR, 1.6; 95% CI, 1.2-2.0) and other petroleum products (RR, 1.6; 95% CI, 1.3-2.1). Asbestos, petroleum products and dry-cleaning solvents appear to merit further investigation, in view of the relationship between risk and duration of employment or exposure and after adjustment for confounding. There was a negative association between RCC and education, but it was not consistent across all centers. Overall, the results of our multicenter case-control study suggest that occupation may be more important in the etiology of RCC than indicated by earlier studies.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Nyckelord

Aged
Carcinoma
Renal Cell/*epidemiology
Case-Control Studies
Educational Status
Female
Humans
Kidney Neoplasms/*epidemiology
Male
Middle Aged
*Occupations
Odds Ratio
Risk
Smoking

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