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Additional evidence against shared environmental contributions to attention-deficit/hyperactivity problems

Burt, S. Alexandra (författare)
Department of Psychology, Michigan State University, East Lansing, United States
Larsson, Henrik, 1975- (författare)
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Lichtenstein, Paul (författare)
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
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Klump, Kelly L (författare)
Department of Psychology, Michigan State University, East Lansing, United States
Lichtenstein, P (författare)
Karolinska Institutet
Burt, SA (författare)
Klump, KL (författare)
Larsson, H (författare)
Karolinska Institutet
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 (creator_code:org_t)
New York, USA : Springer, 2012
2012
Engelska.
Ingår i: Behavior Genetics. - New York, USA : Springer. - 0001-8244 .- 1573-3297. ; 42:5, s. 711-721
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • A recent meta-analysis "Burt (Psychol Bull 135:608-637, 2009)" indicated that shared environmental influences (C) do not contribute to Attention-Deficit/Hyperactivity Disorder (ADHD). Unfortunately, the meta-analysis relied almost exclusively on classical twin studies. Although useful in many ways, some of the assumptions of the classical twin model (e.g., dominant genetic and shared environmental influences do not simultaneously influence the phenotype) can artifactually decrease estimates of C. There is thus a need to confirm that dominant genetic influences are not suppressing estimates of C on ADHD. The current study sought to do just this via the use of a nuclear twin family model, which allows researchers to simultaneously model and estimate dominant genetic and shared environmental influences. We examined two independent samples of child twins: 312 pairs from the Michigan State University Twin Registry and 854 pairs from the PrE School Twin Study in Sweden. Shared environmental influences were found to be statistically indistinguishable from zero and to account for less than 5 % of the variance. We conclude that the presence of dominant genetic influences does not account for the absence of C on ADHD.

Ämnesord

NATURAL SCIENCES  -- Biological Sciences -- Genetics (hsv//eng)
NATURVETENSKAP  -- Biologiska vetenskaper -- Genetik (hsv//swe)
SOCIAL SCIENCES  -- Psychology (hsv//eng)
SAMHÄLLSVETENSKAP  -- Psykologi (hsv//swe)
NATURVETENSKAP  -- Biologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences (hsv//eng)

Nyckelord

ADHD
nuclear twin family model
shared environment
genetic influences

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