SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:DiVA.org:oru-75707"
 

Sökning: onr:"swepub:oai:DiVA.org:oru-75707" > Risk of bacterial p...

Risk of bacterial pneumonia and pneumococcal infection in youths with celiac disease - A population-based study

Canova, Cristina, (författare)
Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Padua, Italy
Ludvigsson, Jonas F., 1969- (författare)
Örebro universitet, Institutionen för medicinska vetenskaper, Region Örebro län, Department Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Örebro University Hospital, Örebro University, Örebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, USA
Baldo, Vincenzo, (författare)
Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Padua, Italy
visa fler...
Amidei, Claudio Barbiellini, (författare)
Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Padua, Italy
Zanier, Loris, (författare)
Epidemiological Service, Health Directorate, Udine, Italy
Zingone, Fabiana, (författare)
Department of Surgery, Oncology and Gastroenterology, Gastroenterology Section, University Hospital of Padua, Padua, Italy
visa färre...
Örebro universitet Institutionen för medicinska vetenskaper. (creator_code:org_t)
Region Örebro län (creator_code:org_t)
2019
Engelska.
Ingår i: Digestive and Liver Disease. - Elsevier. - 1590-8658. ; 51:8, s. 1101-1105
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Objective: Assess the risk of hospitalizations for bacterial pneumonia or pneumococcal infections, in a cohort of young individuals with celiac disease (CD) compared to matched references.Study design: The cohort consists of 213,635 individuals, born in 1989-2012 and resident in Friuli-Venezia Giulia (Italy). Through pathology reports, hospital discharge records or co-payment exemptions, we identified 1294 CD patients and 6470 reference individuals matched by gender and birth year. We considered hospital admissions for first episodes of bacterial pneumonia and pneumococcal infections. Hazard ratios (HRs) for episodes after CD diagnosis were calculated with Cox regression and odds ratios (OR) for the ones before CD diagnosis with conditional logistic regression. Further analyses were performed on unvaccinated follow-up periods.Results: 14 CD patients (in 9450 person-years) and 42 references (in 48,335 person-years) experienced a first episode of bacterial pneumonia, with an increased risk among CD patients (HR 1.82; 95% CI 0.98-3.35). Risks of bacterial pneumonia were significantly increased before CD diagnosis and especially the year before CD diagnosis (OR 6.00, 95% CI 1.83-19.66). Risks of pneumococcal infections showed a non-significant increase in CD patients.Conclusions: CD children and youth showed an increased risk of bacterial pneumonia, especially in proximity to CD diagnosis. Anti-pneumococcal vaccination should be recommended to all young CD patients. (C) 2019 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

Nyckelord

Coeliac disease
Cohort study
Pediatric population
Pneumococcal infection

Publikations- och innehållstyp

art (ämneskategori)
ref (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Sök utanför SwePub

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy