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Sökning: onr:"swepub:oai:DiVA.org:sh-22924" > Trends in cancer of...

Trends in cancer of the cervix uteri in Sweden following cytological screening

Bergström, R. (författare)
Sparén, Pär, (författare)
Södertörns högskola, SCOHOST (Stockholm Centre on Health of Societies in Transition), Karolinska Institute
Adami, H. -O (författare)
1999
Engelska.
Ingår i: British Journal of Cancer. - 0007-0920 .- 1532-1827. ; 81:1, s. 159-166
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • <p>Trends in cervical cancer incidence following the introduction of screening have mostly been studied using cross-sectional data and not analysed separately for squamous cell cancer and adenocarcinomas. Using Swedish nationwide data on incidence and mortality, we analysed trends during more than 3 decades and fitted Poisson-based age-period-cohort models, and also investigated whether screening has reduced the incidence of adenocarcinomas of the cervix. The incidence of reported cancer in situ increased rapidly during 1958-1967. Incidence rates of squamous cell cancer, fairly stable before 1968, decreased thereafter by 4-6% yearly in women aged 40-64, with a much smaller magnitude in younger and older women. An age-cohort model indicated a stable 70-75% reduction in incidence for women born 1940 and later compared with those born around 1923. The incidence of adenocarcinomas doubled during the 35-year study period. The mortality rate increased by 3.6% before 1968 and decreased by 4.0% yearly thereafter. Although a combination of organized and opportunistic screening can reduce the incidence of squamous cell cancer substantially, the incidence of adenocarcinomas appears uninfluenced by screening.</p>

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  (hsv//swe)
MEDICAL AND HEALTH SCIENCES  (hsv//eng)

Nyckelord

Adenocarcinoma
Age-period-cohort models
Cervical cancer
Cytological screening
Squamous cell cancer
article
cancer screening
carcinoma in situ
cytology
female
human
major clinical study
priority journal
squamous cell carcinoma
statistical model
Sweden
uterine cervix cancer
Adult
Aged
Aged
80 and over
Carcinoma
Squamous Cell
Cohort Studies
Humans
Incidence
Mass Screening
Middle Aged
Poisson Distribution
Uterine Cervical Neoplasms

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Av författaren/redakt...
Bergström, R.
Sparén, Pär
Adami, H. -O
Om ämnet
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Södertörns högskola

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