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Restrictive spirometric pattern in the general adult population methods of defining the condition and consequences on prevalence

Backman, Helena, (författare)
Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
Eriksson, Berne, (författare)
Department of Internal Medicine, Central County Hospital of Halmstad, Halmstad
Hedman, Linnea, (författare)
Luleå tekniska universitet, Omvårdnad, Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
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Stridsman, Caroline, (författare)
Luleå tekniska universitet, Omvårdnad
Jansson, Sven-Arne, (författare)
Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
Sovijärvi, Anssi, (författare)
Department of Clinical Physiology and Nuclear Medicine, HUS Medical Imaging Centre, Helsinki University Central Hospital
Lindberg, Anne, (författare)
Department of Public Health and Clinical Medicine, Division of Medicine/the OLIN unit, Umeå University
Rönmark, Eva, (författare)
Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
Lundbäck, Bo, (författare)
Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
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Luleå tekniska universitet Institutionen för hälsovetenskap. Omvårdnad. (creator_code:org_t)
Umeå universitet Medicinska fakulteten. Institutionen för folkhälsa och klinisk medicin. Yrkes- och miljömedicin. (creator_code:org_t)
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Umeå universitet Medicinska fakulteten. Institutionen för folkhälsa och klinisk medicin. Medicin. (creator_code:org_t)
Göteborgs universitet Sahlgrenska akademin. Krefting Research Centre. 
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2016
Engelska.
Ingår i: Respiratory Medicine. - Elsevier. - 0954-6111. ; 120, s. 116-123
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • BACKGROUND: Attempts have been made to use dynamic spirometry to define restrictive lung function, but the definition of a restrictive spirometric pattern (RSP) varies between studies such as BOLD and NHANES. The aim of this study was to estimate the prevalence and risk factors of RSP among adults in northern Sweden based on different definitions.METHODS: In 2008-2009 a general population sample aged 21-86y within the obstructive lung disease in northern Sweden (OLIN) studies was examined by structured interview and spirometry, and 726 subjects participated (71% of invited). The prevalence of RSP was calculated according to three different definitions based on pre-as well as post-bronchodilator spirometry: 1) FVC < 80% & FEV1/FVC > 0.7 2) FVC < 80% & FEV1/FVC > LLN 3) FVC < LLN & FEV1/FVC > LLN RESULTS: The three definitions yielded RSP prevalence estimates of 10.5%, 11.2% and 9.4% respectively, when based on pre-bronchodilator values. The prevalence was lower when based on post-bronchodilator values, i.e. 7.3%, 7.9% and 6.6%. According to definition 1 and 2, the RSP prevalence increased by age, but not according to definition 3. The overlap between the definitions was substantial. When corrected for confounding factors, manual work in industry and diabetes with obesity were independently associated with an increased risk for RSP regardless of definition.CONCLUSIONS: The prevalence of RSP was 7-11%. The prevalence estimates differed more depending on the choice of pre- compared to post-bronchodilator values than on the choice of RSP definition. RSP was, regardless of definition, independently associated with manual work in industry and diabetes with obesity.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskaper -- Omvårdnad (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nursing (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskaper -- Miljömedicin och yrkesmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Environmental Health and Occupational Health (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Nyckelord

Nursing
Omvårdnad
Health Science
Hälsovetenskap
Restriction
Spirometry
Prevalence
Risk factor
General population

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