SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:DiVA.org:umu-96194"
 

Sökning: onr:"swepub:oai:DiVA.org:umu-96194" > The Computerized Ge...

The Computerized General Neuropsychological INPH Test (CoGNIT) revealed improvement in Idiopathic Normal Pressure Hydrocephalus (INPH) after shunt surgery

Behrens, Anders (författare)
Elgh, Eva (författare)
Leijon, Göran (författare)
visa fler...
Kristensen, Bo (författare)
Eklund, Anders (författare)
Malm, Jan (författare)
visa färre...
language:D_t.
  • Annan publikation (övrigt vetenskapligt)
Abstract Ämnesord
Stäng  
  • <p>Background</p><p>We have developed the COmputerized General Neuropsychological INPH Test (CoGNIT) dedicated for patients with idiopathic normal pressure hydrocephalus (INPH). Previously, validity and reliability of included tests have been established. The aim was to evaluate the battery’s sensitivity to detect cognitive changes after shunt surgery in INPH patients.</p><p>Methods</p><p>Preoperatively, thirty-one INPH patients were given CoGNIT, which includes tests assessing memory, executive functions, attention, manual dexterity and psychomotor speed. CoGNIT also includes the Geriatric Depression Scale (GDS). Re-examination was done four months after shunt surgery. Scores and test completion were examined and compared to healthy elderly (n=44).</p><p>Results</p><p>Preoperative INPH test results were significantly lower in all tests compared to healthy. Improvements after shunt surgery were seen in all cognitive domains: memory (Ten-word list test, p&lt;0,01), executive functions (Stroop incongruent, (p&lt;0.05), attention (Two choice reaction test, p&lt;0.01), psychomotor speed (Stroop congruent, p&lt;0.05) and manual dexterity (Four- finger tapping, p&lt;0.01). No ceiling effects were observed. Depressive symptoms were more common in INPH versus healthy and did not change postoperatively. Preoperatively 81 % of INPH patients completed at least eight of the nine included test.</p><p>Conclusions</p><p>CoGNIT is sensitive to cognitive impairment and to investigate changes after shunt surgery in INPH. Completion rates are good. CoGNIT has a potential to be useful in the cognitive assessment of INPH. </p>

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  (hsv//swe)
MEDICAL AND HEALTH SCIENCES  (hsv//eng)

Nyckelord

Neurology
neurologi

Publikations- och innehållstyp

vet (ämneskategori)
ovr (ämneskategori)
vet (ämneskategori)

Till lärosätets databas

Sök utanför SwePub

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy