HD-Zip class III transcription factors control root development through the modulation of ROS levels

• In the Arabidopsis root the distinct spatial distribution of two ROS species, hydrogen peroxide and superoxide, controls a dynamic balance between cell division and cell differentiation. Superoxide accumulates in the root meristem while hydrogen peroxide accumulates in the elongation and differentiation zone. The balance between both species controls cell proliferation. Mutants defective in the developmental control regulators encoded by Class III homeodomain leucine zipper (HD-ZIP III) genes display alterations both in root growth rates and levels of ROS species. A gain-of-function mutant of the PHB HD-Zip III gene presents a short root length and small meristem size, while the multiple loss of HD-Zip genes functionality results in bigger root meristem size. Additionally, gain- and loss-of function mutants present contrasting ROS balances. Our analyses of transcriptome changes upon depleting HD-Zip III levels suggest that the HD-Zip class III transcription factors act upstream of ROS-related genetic pathways controlling meristem size and growth rate. Thus, the HD-Zip transcription factors may act to control root growth, possibly by modulation of ROS levels.

Ämnesord

NATURVETENSKAP  -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)

NATURAL SCIENCES  -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)

Nyckelord

ROS

Plant development

HD-Zip III TFs

Biologi med inriktning mot fysiologisk botanik

Biology with specialization in Physiological Botany

Publikations- och innehållstyp

vet (ämneskategori)

kon (ämneskategori)