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Sökning: onr:"swepub:oai:DiVA.org:uu-297541" > Caesarean delivery ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006851naa a2200565 4500
001oai:DiVA.org:uu-297541
003SwePub
008160623s2016 | |||||||||||000 ||eng|
024a urn:nbn:se:uu:diva-2975412 urn
024a https://doi.org/10.1016/S2352-3026(16)00002-82 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Marcotte, Erin L.u Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.4 aut
2451 0a Caesarean delivery and risk of childhood leukaemia :b a pooled analysis from the Childhood Leukemia International Consortium (CLIC)
264 1c 2016
338 a print2 rdacarrier
520 a Background Results from case-control studies have shown an increased risk of acute lymphoblastic leukaemia (ALL) in young children born by caesarean delivery, and prelabour caesarean delivery in particular; however, an association of method of delivery with childhood leukaemia subtypes has yet to be established. We therefore did a pooled analysis of data to investigate the association between childhood leukaemia and caesarean delivery. Methods We pooled data from 13 case-control studies from the Childhood Leukemia International Consortium done in nine countries (Canada, Costa Rica, Egypt, France, Germany, Greece, Italy, New Zealand, and the USA) for births from 1970-2013. We analysed caesarean delivery overall and by indications that probably resulted in prelabour caesarean delivery or emergency caesarean delivery. We used multivariable logistic regression models, adjusted for child's birthweight, sex, age, ethnic origin, parental education, maternal age, and study, to estimate odds ratios (ORs) and 95% CIs for the risk of ALL and acute myeloid leukaemia (AML) in children aged 0-14 years at diagnosis. Findings The studies provided data for 8780 ALL cases, 1332 AML cases, and 23 459 controls, of which the birth delivery method was known for 8655 (99%) ALL cases, 1292 (97%) AML cases, and 23 351 (> 99%) controls. Indications for caesarean delivery were available in four studies (there were caesarean deliveries for 1061 of 4313 ALL cases, 138 of 664 AML cases, and 1401 of 5884 controls). The OR for all indications of caesarean delivery and ALL was 1.06 (95% CI 0.99-1.13), and was significant for prelabour caesarean delivery and ALL (1.23 [1.04-1.47]; p= 0.018). Emergency caesarean delivery was not associated with ALL (OR 1.02 [95% CI 0.81-1.30]). AML was not associated with caesarean delivery (all indications OR 0.99 [95% CI 0.84-1.17]; prelabour caesarean delivery 0.83 [0.54-1.26]; and emergency caesarean delivery 1.05 [0.63-1.77]). Interpretation Our results suggest an increased risk of childhood ALL after prelabour caesarean delivery. If this association is causal, maladaptive immune activation due to an absence of stress response before birth in children born by prelabour caesarean delivery could be considered as a potential mechanism.
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
700a Thomopoulos, Thomas P.u Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens 11528, Greece.4 aut
700a Infante-Rivard, Claireu McGill Univ, Fac Med, Dept Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada.4 aut
700a Clavel, Jacquelineu Epidemiol & Biostat Sorbonne Paris Cite Ctr, Epidemiol Childhood & Adolescent Canc Team, INSERM, U1153, Villejuif, France.;Paris Descartes Univ, Epidemiol & Biostat Sorbonne Paris Cite Ctr, UMRS 1153, Paris, France.4 aut
700a Petridou, Eleni Thu Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens 11528, Greece.4 aut
700a Schuz, Joachimu Int Agcy Res Canc, Sect Environm & Radiat, 150 Cours Albert Thomas, F-69372 Lyon, France.4 aut
700a Ezzat, Sameerau Menoufia Univ, Natl Liver Inst, Menoufia, Egypt.4 aut
700a Dockerty, John D.u Univ Otago, Dunedin Sch Med, Deans Dept, Dunedin, New Zealand.;Univ Otago, Dunedin Sch Med, Dept Prevent & Social Med, Dunedin, New Zealand.4 aut
700a Metayer, Catherineu Univ Calif Berkeley, Sch Publ Hlth, Berkeley, CA 94720 USA.4 aut
700a Magnani, Corradou Univ Piemonte Orientale, SCDU Epidemiol Tumori, Dipartimento Med Traslaz, Novara, Italy.4 aut
700a Scheurer, Michael E.u Baylor Coll Med, Dept Pediat, Sect Hematol Oncol, Houston, TX 77030 USA.;Texas Childrens Canc Ctr, Houston, TX USA.4 aut
700a Mueller, Beth A.u Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1124 Columbia St, Seattle, WA 98104 USA.;Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA.4 aut
700a Mora, Ana M.u Univ Nacl, Cent Amer Inst Studies Tox Subst, Heredia, Costa Rica.;Boston Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA USA.4 aut
700a Wesseling, Catharinau Univ Nacl, Cent Amer Inst Studies Tox Subst, Heredia, Costa Rica.4 aut
700a Skalkidou, Alkistisu Uppsala universitet,Obstetrik & gynekologi4 aut0 (Swepub:uu)alksk607
700a Rashed, Wafaa M.u Childrens Canc Hosp Egypt 57357, Res Dept, Cairo, Egypt.4 aut
700a Francis, Stephen S.u Univ Calif Berkeley, Sch Publ Hlth, Berkeley, CA 94720 USA.;Univ Calif San Francisco, Neuro & Mol Epidemiol Lab, San Francisco, CA 94143 USA.4 aut
700a Ajrouche, Roulau Epidemiol & Biostat Sorbonne Paris Cite Ctr, Epidemiol Childhood & Adolescent Canc Team, INSERM, U1153, Villejuif, France.;Paris Descartes Univ, Epidemiol & Biostat Sorbonne Paris Cite Ctr, UMRS 1153, Paris, France.4 aut
700a Erdmann, Friederikeu Int Agcy Res Canc, Sect Environm & Radiat, 150 Cours Albert Thomas, F-69372 Lyon, France.4 aut
700a Orsi, Laurentu Epidemiol & Biostat Sorbonne Paris Cite Ctr, Epidemiol Childhood & Adolescent Canc Team, INSERM, U1153, Villejuif, France.;Paris Descartes Univ, Epidemiol & Biostat Sorbonne Paris Cite Ctr, UMRS 1153, Paris, France.4 aut
700a Spector, Logan G.u Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.4 aut
710a Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.b Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens 11528, Greece.4 org
773g 3:4, s. E176-E185
773g 3:4, s. E176-E185
773t The Lancet Haematologyg 3:4, s. E176-E185q 3:4<E176-E185x 2352-3026
8564 8u http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-297541x lärosäteslänky Till lärosätets (uu) databas
8564 8u https://doi.org/10.1016/S2352-3026(16)00002-8

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