BGI Shenzhen, China Natl GeneBank, Shenzhen 518083, Peoples R China.;King Abdulaziz Univ, Princess Al Jawhara Ctr Excellence Res Hereditary, Jeddah 21589, Saudi Arabia.;Univ Copenhagen, Dept Biol, DK-2200 Copenhagen, Denmark.;Macau Univ Sci & Technol, Taipa 999078, Peoples R China.;Univ Hong Kong, Dept Med, Hong Kong, Hong Kong, Peoples R China.
Zhang, Guojie (författare)
BGI Shenzhen, China Natl GeneBank, Shenzhen 518083, Peoples R China.;Univ Copenhagen, Dept Biol, Ctr Social Evolut, DK-2100 Copenhagen, Denmark.
Background: Penguins are flightless aquatic birds widely distributed in the Southern Hemisphere. The distinctive morphological and physiological features of penguins allow them to live an aquatic life, and some of them have successfully adapted to the hostile environments in Antarctica. To study the phylogenetic and population history of penguins and the molecular basis of their adaptations to Antarctica, we sequenced the genomes of the two Antarctic dwelling penguin species, the Adelie penguin [Pygoscelis adeliae] and emperor penguin [Aptenodytes forsteri]. Results: Phylogenetic dating suggests that early penguins arose similar to 60 million years ago, coinciding with a period of global warming. Analysis of effective population sizes reveals that the two penguin species experienced population expansions from similar to 1 million years ago to similar to 100 thousand years ago, but responded differently to the climatic cooling of the last glacial period. Comparative genomic analyses with other available avian genomes identified molecular changes in genes related to epidermal structure, phototransduction, lipid metabolism, and forelimb morphology. Conclusions: Our sequencing and initial analyses of the first two penguin genomes provide insights into the timing of penguin origin, fluctuations in effective population sizes of the two penguin species over the past 10 million years, and the potential associations between these biological patterns and global climate change. The molecular changes compared with other avian genomes reflect both shared and diverse adaptations of the two penguin species to the Antarctic environment.