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Sökning: onr:"swepub:oai:DiVA.org:uu-311505" > Reproductive histor...

  • Bjørge, Tone,Univ Bergen, Dept Global Publ Hlth & Primary Care, Bergen, Norway.;Canc Registry Norway, Oslo, Norway. (författare)

Reproductive history and risk of colorectal adenocarcinoma in parous women a Nordic population-based case-control study

  • E-artikel/E-kapitelEngelska2016

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-311505
  • 10.1038/bjc.2016.315doi
  • 27701386pmid
  • urn:nbn:se:uu:diva-311505urn

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Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Published
  • 11
  • <p>Background: Data are conflicting regarding the role of endogenous sex hormones in colorectal carcinogenesis. In this large population-based study, we pooled data from birth and cancer registries in four Nordic countries, to evaluate the risk of colorectal adenocarcinoma in relation to women's reproductive history. Methods: We conducted a population-based case-control study among women registered in Nordic birth registries. The study included colorectal adenocarcinoma cases diagnosed in Denmark, Finland, Norway, and Sweden during 1967-2013 and up to 10 matched controls per case, in total 22 185 cases and 220 246 controls. Odds ratios (ORs) with 95% confidence intervals (95% CIs) were derived from conditional logistic regression models. We had limited information available on possible confounders. Results: We found no evidence for associations between colorectal adenocarcinoma and parity, age at first and last birth, and time since first and last birth. The risk estimates were also close to unity for specific cancer subsites (proximal and distal colon and rectum). As well, when the analyses were stratified on menopausal status, parity, and mother's year of birth, no indication of associations was found. Conclusions: In this large, Nordic population-based study, no evidence for associations was found between women's reproductive history and colorectal adenocarcinoma in parous women.</p>

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Gissler, Mika,Natl Inst Hlth & Welf THL, Helsinki, Finland.(SwePub:) (författare)
  • Ording, Anne Gulbech,Aarhus Univ Hosp, Dept Clin Epidemiol, Aarhus, Denmark.(SwePub:) (författare)
  • Engeland, Anders,Univ Bergen, Dept Global Publ Hlth & Primary Care, Bergen, Norway.;Norwegian Inst Publ Hlth, Dept Pharmacoepidemiol, Div Mental & Phys Hlth, Bergen, Norway.(SwePub:) (författare)
  • Glimelius, Ingrid,Uppsala universitet, Experimentell och klinisk onkologi, Karolinska Inst, Clin Epidemiol Unit, Dept Med, Stockholm, Sweden.;Karolinska Univ Hosp, Stockholm, Sweden.(SwePub:uu) (författare)
  • Leinonen, Maarit,Finnish Canc Registry, Canc Soc Finland, Helsinki, Finland.(SwePub:) (författare)
  • Sørensen, Henrik Toft,Aarhus Univ Hosp, Dept Clin Epidemiol, Aarhus, Denmark.(SwePub:) (författare)
  • Tretli, Steinar,Canc Registry Norway, Oslo, Norway.(SwePub:) (författare)
  • Ekbom, Anders,Karolinska Inst, Clin Epidemiol Unit, Dept Med, Stockholm, Sweden.;Karolinska Univ Hosp, Stockholm, Sweden.(SwePub:) (författare)
  • Troisi, Rebecca,NCI, Div Canc Epidemiol & Genet, NIH, Dept Hlth & Human Serv, Bethesda, MD USA.(SwePub:) (författare)
  • Grotmol, Tom,Canc Registry Norway, Oslo, Norway.(SwePub:) (författare)

Sammanhörande titlar

  • Ingår i:British Journal of Cancer0007-09201532-1827115:11, s. 1416-1420

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