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Sökning: onr:"swepub:oai:DiVA.org:uu-385967" > Long-term outcome a...

Long-term outcome after segmental colonic resection for slow transit constipation

Tsimogiannis, Konstantinos, (författare)
Uppsala universitet, Gastrointestinalkirurgi
Karlbom, Urban, (författare)
Uppsala universitet, Gastrointestinalkirurgi
Lundin, Erik, (författare)
Uppsala universitet, Gastrointestinalkirurgi
visa fler...
Graf, Wilhelm, (författare)
Uppsala universitet, Gastrointestinalkirurgi
visa färre...
2019
Engelska.
Ingår i: International Journal of Colorectal Disease. - SPRINGER. - 0179-1958 .- 1432-1262. ; 34:6, s. 1013-1019

  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • <p>PurposeColectomy with ileorectal anastomosis (IRA) is the most common surgical procedure for slow transit constipation (STC). A hemicolectomy has been suggested as an alternative to IRA with good short-term results. However, long-term results are unknown. The aim of this study was to evaluate the long-term results after hemicolectomy as a treatment for STC.MethodsFifty patients with STC were selected for right- or left-sided hemicolectomy after evaluation with colonic scintigraphy from 1993 to 2008. Living patients (n=43) received a bowel function questionnaire and a questionnaire about patient-reported outcome.ResultsAfter a median follow-up of 19.8years, 13 patients had undergone rescue surgery (n=12) or used irrigation (n=1) and were classified as failures. In all, 30 were evaluable for functional outcome and questionnaire data for 19 patients (due to 11 non-responding) could be analysed. Two reported deterioration after several years and were also classified as failures. Median stool frequency remained increased from 1 per week at baseline to 5 per week at long-term follow-up (p=0.001). Preoperatively, all patients used laxatives, whereas 12 managed without laxatives at long-term follow-up (p=0.002). There was some reduction in other constipation symptoms but not statically significant. In the patients' global assessment, 10 stated a very good result, seven a good result and two a poor result.ConclusionsHemicolectomy for STC increases stool frequency and reduces laxative use. Long-term success rate could range between 17/50 (34%) and 35/50 (70%) depending on outcome among non-responders.</p>

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

Nyckelord

Slow transit constipation
Segmental resection
Colonic functional disorders
Long-term follow-up

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Tsimogiannis, Ko ...
Karlbom, Urban
Lundin, Erik
Graf, Wilhelm
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