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Gender differences in the treatment of patients with bipolar disorder: A study of 7354 patients

Karanti, Alina, (författare)
University of Gothenburg, Sweden
Bobeck, Christian, (författare)
Linköpings universitet, Statistik, Linköpings universitet, Tekniska högskolan
Osterman, Maja, (författare)
Linköpings universitet, Statistik, Linköpings universitet, Tekniska högskolan
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Kardell, Mathias, (författare)
University of Gothenburg, Sweden
Tidemalm, Dag, (författare)
Karolinska Institute, Sweden
Runeson, Bo, (författare)
Karolinska Institute, Sweden
Lichtenstein, Paul, (författare)
Karolinska Institute, Sweden
Landen, Mikael, (författare)
University of Gothenburg, Sweden; Karolinska Institute, Sweden
Landén, Mikael, 1966- (författare)
Göteborgs universitet, Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi, Gothenburg University, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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Linköpings universitet Institutionen för datavetenskap. Statistik. (creator_code:org_t)
Linköpings universitet Tekniska högskolan. (creator_code:org_t)
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Göteborgs universitet Sahlgrenska akademin. Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi. 
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2015
Engelska.
Ingår i: Journal of Affective Disorders. - 0165-0327. ; 174, s. 303-309
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background: Gender differences in treatment that are not supported by empirical evidence have been reported in several areas of medicine. Here, the aim was to evaluate potential gender differences in the treatment for bipolar disorder. Methods: Data was collected from the Swedish National Quality Assurance Register for bipolar disorder (BipolaR). Baseline registrations from the period 2004-2011 of 7354 patients were analyzed. Multiple logistic regression analysis was used to study the impact of gender on interventions. Results: Women were more often treated with antidepressants, lamotrigine, electroconvulsive therapy, benzodiazepines, and psychotherapy. Men were more often treated with lithium. There were no gender differences in treatment with mood stabilizers as a group, neuroleptics, or valproate. Subgroup analyses revealed that ECT was more common in women only in the bipolar l subgroup. Contrariwise, lamotrigine was more common in women only in the bipolar II subgroup. Limitations: As BipolaR contains data on outpatient treatment of persons with bipolar disorder in Sweden, it is unclear if these Findings translate to inpatient care and to outpatient treatment in other countries. Conclusions: Men and women with bipolar disorder receive different treatments in routine clinical settings in Sweden. Gender differences in level of functioning, bipolar subtype, or severity of bipolar disorder could not explain the higher prevalence of pharmacological treatment, electroconvulsive therapy, and psychotherapy in women. Our results suggest that clinicians treatment decisions are to some extent unduly influenced by patients gender. (C) 2014 Elsevier B.V. All rights reserved.

Ämnesord

NATURVETENSKAP  -- Data- och informationsvetenskap (hsv//swe)
NATURAL SCIENCES  -- Computer and Information Science (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

Nyckelord

Bipolar disorder; Gender; Drug therapy; Electroconvulsive therapy; Psychotherapy
Bipolar disorder
Gender
Drug therapy
Electroconvulsive therapy
Psychotherapy
ACUTE MYOCARDIAL-INFARCTION
POLYCYSTIC OVARIAN SYNDROME
TREATMENT
RESPONSE
ELECTROCONVULSIVE-THERAPY
SEX-DIFFERENCES
ACUTE MANIA
I
DISORDER
STEP-BD
WOMEN
VALPROATE

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