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A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up

Backman, Helena, (författare)
Umeå universitet, Yrkes- och miljömedicin, The OLIN unit
Hedman, Linnea, (författare)
Umeå universitet, Yrkes- och miljömedicin, Department of Health Sciences, Luleå University, Luleå, Sweden, The OLIN unit ; Arcum
Stridsman, Caroline (författare)
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Jansson, Sven-Arne, (författare)
Umeå universitet, Yrkes- och miljömedicin, The OLIN unit
Lindberg, Anne, (författare)
Umeå universitet, Medicin, The OLIN unit
Lundbäck, Bo (författare)
Rönmark, Eva, (författare)
Umeå universitet, Yrkes- och miljömedicin, The OLIN unit
Ronmark, E. (författare)
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Umeå universitet Medicinska fakulteten. Institutionen för folkhälsa och klinisk medicin. Yrkes- och miljömedicin. (creator_code:org_t)
Umeå universitet Medicinska fakulteten. Institutionen för folkhälsa och klinisk medicin. Medicin. (creator_code:org_t)
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Göteborgs universitet Sahlgrenska akademin. Krefting Research Centre. 
Göteborgs universitet Sahlgrenska akademin. Institutionen för medicin. 
Luleå tekniska universitet Institutionen för hälsovetenskap. Omvårdnad. (creator_code:org_t)
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2017
Engelska.
Ingår i: European Clinical Respiratory Journal. - 2001-8525. ; 4
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Abstract Ämnesord
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  • Background and objective: Asthma is a major public health concern. The aim of this study was to characterize a large population-based cohort of adults with asthma, and to study factors associated with all-cause mortality and non-participation in a long-term follow-up. Design: Random and stratified samples from five population-based cohorts were clinically examined during 1986-2001, and all subjects with asthma were included in the study (n = 2055, age 19-72 years, 55% women). Independent associations between different risk factors and (i) mortality and (ii) non-participation in a clinical follow-up in 2012-2014 were estimated. Results: In 1986-2001, 95% reported any wheeze and/or attacks of shortness of breath in the past 12 months, and/or asthma medication use. Over the up to 28 years of follow-up time, the cumulative mortality was 22.7%. Male gender, current smoking, and lower forced expiratory volume in 1 sec of predicted (FEV1% of predicted) were independent risk factors for mortality, while obesity was associated with non-participation in the follow-up. Older ages, ischemic heart disease, and low socioeconomic status were associated with both mortality and non-participation. Conclusions: The risk factors associated with mortality in this adult population-based asthma cohort were similar to those commonly identified in general population samples, i.e. male gender, current smoking, and lower FEV1% of predicted, while obesity was associated with non-participation in a long-term follow-up. Ischemic heart disease, low socioeconomic status, and older ages were associated with both mortality and non-participation.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskaper -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskaper -- Omvårdnad (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nursing (hsv//eng)

Nyckelord

Public health
risk factors
natural history
obesity
ischemic heart disease
socioeconomic status
OBSTRUCTIVE LUNG-DISEASE
RESPIRATORY HEALTH SURVEY
NORTHERN SWEDEN
ONSET ASTHMA
BRONCHIAL RESPONSIVENESS
POSTAL QUESTIONNAIRE
GENERAL-POPULATION
PULMONARY-DISEASE
1
075 OUTPATIENTS
REMISSION
Nursing
Omvårdnad

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