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Phenotypic and genotypic characteristics of women in relation to personality traits.

Baghaei, Fariba, 1964- (författare)
Göteborgs universitet, Hjärt-kärlinstitutionen, Gothenburg University, Cardiovascular Institute
Rosmond, Roland, 1966- (författare)
Göteborgs universitet, Hjärt-kärlinstitutionen, Gothenburg University, Cardiovascular Institute
Landén, Mikael, 1966- (författare)
Göteborgs universitet, Institutionen för klinisk neurovetenskap, Sektionen för psykiatri, Gothenburg University, Institute of Clinical Neurosciences, Section of Psychiatry
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Westberg, Lars, 1973- (författare)
Göteborgs universitet, Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi, Gothenburg University, Institute of Physiology and Pharmacology, Dept of Pharmacology
Hellstrand, Monika, 1955- (författare)
Göteborgs universitet, Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi, Gothenburg University, Institute of Physiology and Pharmacology, Dept of Pharmacology
Holm, Göran, 1942- (författare)
Göteborgs universitet, Hjärt-kärlinstitutionen, Gothenburg University, Cardiovascular Institute
Eriksson, Elias, 1956- (författare)
Göteborgs universitet, Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi, Gothenburg University, Institute of Physiology and Pharmacology, Dept of Pharmacology
Björntorp, Per, 1931- (författare)
Göteborgs universitet, Hjärt-kärlinstitutionen, Gothenburg University, Cardiovascular Institute
Landen, M, (författare)
Karolinska Institutet
Bjorntorp, P (författare)
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Göteborgs universitet Sahlgrenska akademin. Hjärt-kärlinstitutionen. 
Göteborgs universitet Sahlgrenska akademin. Institutionen för klinisk neurovetenskap, Sektionen för psykiatri. 
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Göteborgs universitet Sahlgrenska akademin. Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi. 
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2003
Engelska.
Ingår i: International journal of behavioral medicine. - 1070-5503. ; 10:4, s. 365-78
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • The associations were examined in women between personality traits and steroid hormones, particularly androgens, as well as polymorphisms in genes regulating androgen concentration and effects. Women, all 42 years of age and premenopausal (n = 270), were recruited randomly. Conventional "masculine" and "feminine" personality traits were examined by questionnaire and set in relation to psychosocial and socioeconomic conditions, behavior in childhood, hormones, risk factors for disease, and polymorphisms in microsatellites in the CYP aromatase and the androgen receptor gene. The proportions of personality traits considered as being dominated by "masculinity" (M) or "femininity" (F) were 44.9%, respectively 15.0%, the rest consisting of a combination of M and F (33.2%) or "undifferentiated" (6.9%). M characteristics were positively associated with education, sporting, self-confidence, and good adaptation to work situation. M scores correlated with reports of "tomboyism" as girls. There was essentially no difference in hormones or disease risk factors between M and F women. The number of (CAG) repeats in the microsatellite of the transactivating domain of the androgen receptor was 19 (2.3; M and SD). M characteristics were more pronounced in the presence of longer repeat stretches (n > 20). No associations were found with F scores. There were no significant associations to the number of tetranucleotide repeats (TTTA) in the fourth introne of the aromatase gene. It was concluded that a majority of women showed M type of personality traits, associated with normal hormones, somatic health, and a long microsatellite in the transactivating domain of the AR gene.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)

Nyckelord

Adult
Androgens
genetics
Aromatase
genetics
Female
Gender Identity
Genotype
Humans
Personality
genetics
Phenotype
Polymorphism
Genetic
Psychosexual Development
Questionnaires
Receptors
Androgen
genetics
Self Concept
Socioeconomic Factors
Sweden

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