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Aspiration as a lat...
Aspiration as a late complication after accelerated versus conventional radiotherapy in patients with head and neck cancer
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- Lindblom, Ulrika (författare)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Nilsson, Per (författare)
- Lund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Gärskog, Ola (författare)
- Umeå universitet,Öron- näs- och halssjukdomar,Umea Univ, Dept Clin Sci, Otorhinolaryngol, SE-90187 Umea, Sweden.
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- Kjellén, Elisabeth (författare)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Laurell, Göran (författare)
- Uppsala universitet,Umeå universitet,Öron- näs- och halssjukdomar,Öron-, näs- och halssjukdomar,Umea Univ, Dept Clin Sci, Otorhinolaryngol, SE-90187 Umea, Sweden.
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- Wahlberg, Peter (författare)
- Lund University,Lunds universitet,Öron-, näs- och halssjukdomar, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Otorhinolaryngology (Lund),Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Zackrisson, Björn (författare)
- Umeå universitet,Onkologi,Umea Univ, Dept Radiat Sci, Oncol, SE-90187 Umea, Sweden.
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- Levring Jäghagen, Eva, 1962- (författare)
- Umeå universitet,Institutionen för odontologi,Umea Univ, Dept Odontol Oral & Maxillofacial Radiol, SE-90187 Umea, Sweden.
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(creator_code:org_t)
- 2016-01-12
- 2016
- Engelska.
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Ingår i: Acta Oto-Laryngologica. - : Taylor & Francis. - 0001-6489 .- 1651-2251. ; 136:3, s. 304-311
- Relaterad länk:
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http://www.ncbi.nlm....
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Conclusion Neck dissection after radiotherapy increased the risk of aspiration as a late effect in a sub-sample of patients treated for head and neck cancer in the ARTSCAN study. Patients treated with accelerated fractionation (AF) developed aspiration, with or without coughing, more frequently than patients treated with conventional fractionation (CF). Objectives A long-term follow-up study was conducted to determine the frequency of aspiration as a late effect in patients with head and neck cancer treated with AF or CF. Method One-hundred and eight patients were recruited from two centres of the Swedish multi-centre study, ARTSCAN, where AF and CF were compared. Patients with positive lymph nodes were treated with neck dissection after completing radiotherapy. The follow-up was performed at a median of 65 months after initiation of radiotherapy and included an ENT and a videofluoroscopic examination. Results Aspiration was found in 51/108 (47%) and silent aspiration in 34/96 (35%) patients. Neck dissection (n = 47 patients) was significantly associated with both aspiration and silent aspiration. Aspiration was more common among patients treated with AF (34/61; 56%) compared to CF (17/47; 36%; p = 0.053). Silent aspiration was also more common after AF (24/54; 44%) than after CF (10/42; 24%; p = 0.052).
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oto-rhino-laryngologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Otorhinolaryngology (hsv//eng)
Nyckelord
- Late effect
- dysphagia
- follow-up
- neck dissection
- sequelae
- swallowing disorders
- videofluoroscopy
- Oncology
- onkologi
- odontologi
- Odontology
- Radiology
- radiologi
- radiofysik
- radiation physics
- Oto-Rhino-Laryngology
- oto-rhino-laryngologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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