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Evaluating national...
Evaluating national guidelines for the prophylactic treatment of respiratory syncytial virus in children with congenital heart disease
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- Granbom, Elin, 1986- (författare)
- Umeå universitet,Pediatrik
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- Fernlund, Eva (författare)
- Östergötlands Läns Landsting,Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Barn- och ungdomskliniken i Linköping,Department of Paediatrics, University Hospital of Linköping and Children's Heart Centre, Lund, Sweden
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- Sunnegardh, Jan (författare)
- Department of Cardiology at the Queen Silvia Children′s Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden
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- Lundell, Bo (författare)
- Paediatric Cardiology, Astrid Lindgren Children's Hospital, Stockholm, Sweden
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- Naumburg, Estelle (författare)
- Umeå universitet,Pediatrik
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(creator_code:org_t)
- 2014-07-02
- 2014
- Engelska.
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Ingår i: Acta Pædiatrica. - : Wiley. - 1651-2227 .- 0803-5253. ; 103:8, s. 840-845
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Aim: This is the first study to evaluate compliance with the 2003 Swedish national guidelines for prophylactic treatment of respiratory syncytial virus (RSV) in children with congenital heart disease (CHD). We estimated the relative risk (RR) of children with CHD being hospitalised with a RSV infection, studied the extent to which RSV prophylactic treatment with palivizumab corresponded to the guidelines and determined the morbidity of children with CHD who developed RSV infection despite prophylaxis. Methods: This national observational study comprised prospectively registered data on 219 children with CHD treated with palivizumab, medical records on RSV cases and information on hospitalisation rates of children with CHD and RSV infection. Results: The calculated RR of children with CHD being hospitalised with RSV infection was 2.06 (950/0 Cl 1.6-2.6; p < 0.0001) compared with children without CHD. Approximately half of the patients (49%) born before the RSV season and 25% born during the RSV season did not start treatment as recommended by the guidelines. Conclusion: Having CHD increased the rate and estimated RR of children being hospitalised with RSV infection. The guidelines were not followed for about half of the children born before a RSV season and a quarter of the children born during a RSV season and need updating.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- Congenital heart disease
- Palivizumab
- Prophylaxis
- Respiratory
- syncytial virus
- Swedish national guidelines
- Congenital heart disease; Palivizumab; Prophylaxis; Respiratory syncytial virus; Swedish national guidelines
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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