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Sökning: onr:"swepub:oai:lup.lub.lu.se:5200f840-92a1-4728-8089-d5f19975f33b" > Quantitative diffus...

Quantitative diffusion coefficient maps using fast spin-echo MRI

Brockstedt, Sara, (författare)
Lunds universitet, Lund University, Medicinska fakulteten, Faculty of Medicine, Institutionen för kliniska vetenskaper, Lund, Department of Clinical Sciences, Lund, Sektion V, Section V, Medicinsk strålningsfysik, Lund, Medical Radiation Physics, Lund
Thomsen, C (författare)
Wirestam, Ronnie, (författare)
Lunds universitet, Lund University, Medicinska fakulteten, Faculty of Medicine, Institutionen för kliniska vetenskaper, Lund, Department of Clinical Sciences, Lund, Sektion V, Section V, Medicinsk strålningsfysik, Lund, Medical Radiation Physics, Lund
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Holtås, Stig, (författare)
Lunds universitet, Lund University, Medicinska fakulteten, Faculty of Medicine, Institutionen för kliniska vetenskaper, Lund, Department of Clinical Sciences, Lund, Sektion V, Section V, Diagnostisk radiologi, Lund, Diagnostic Radiology, (Lund)
Ståhlberg, Freddy, (författare)
Lunds universitet, Lund University, Medicinska fakulteten, Faculty of Medicine, Institutionen för kliniska vetenskaper, Lund, Department of Clinical Sciences, Lund, Sektion V, Section V, Diagnostisk radiologi, Lund, Diagnostic Radiology, (Lund), Medicinsk strålningsfysik, Lund, Medical Radiation Physics, Lund
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1998
Engelska.
Ingår i: Magnetic Resonance Imaging. - Elsevier. - 1873-5894. ; 16:8, s. 877-886
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • In this work, we have evaluated the performance of a diffusion-sensitive fast spin-echo (FSE) pulse sequence. The proposed pulse sequence utilises velocity-compensating diffusion-encoding gradients and includes the collection of navigator echoes. Spoiler gradients were inserted in the slice-selecting direction to minimise effects from stimulated echoes. Calculations of the b values showed that cross-terms between imaging gradients and diffusion gradients only led to a marginal increase of b values. Pixel-wise calculation of apparent diffusion coefficient (ADC) maps was performed numerically, considering cross-terms between diffusion-encoding and imaging gradients. The sequences investigated used echo train lengths of 16, 8 and 4 echoes and were encoded in either the slice-, frequency- or phase-encoding direction. In order to allow for higher b values a pulse-sequence version using non-motion compensating diffusion-encoding gradients was written. Phantom measurements were performed and the diffusion coefficients of water and acetone were reasonable. Seven healthy volunteers (age 28-50 years) were examined and apparent diffusion coefficient values agreed well with expected values. Diffusion-weighted images, apparent diffusion coefficient maps and images corresponding to the trace of the diffusion tensor of good quality were retrieved in vivo.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

Nyckelord

Navigator echoes Article Outline
Phase correction
Motion-compensating gradients
Diffusion
Fast spin-echo

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