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Sökning: onr:"swepub:oai:lup.lub.lu.se:75bc0a76-db94-4627-9857-9ff65a24b0e8" > Tobacco smoking and...

Tobacco smoking and alcohol consumption as risk factors for thymoma – A European case-control study

Eriksson, Mikael, (författare)
Lunds universitet, Lund University, Medicinska fakulteten, Faculty of Medicine, Institutionen för kliniska vetenskaper, Lund, Department of Clinical Sciences, Lund, Sektion V, Division V, Onkologi och Patologi, Kampradlab, Oncology and Pathology, Kamprad Lab, Skåne University Hospital
Kaerlev, Linda, (författare)
Odense University Hospital, University of Southern Denmark
Johansen, Preben, (författare)
Aalborg University Hospital
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Afonso, Noemia, (författare)
Instituto Português de Oncologia do Porto Francisco Gentil (IPO)
Ahrens, Wolfgang, (författare)
Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH
Costa-Pereira, Altamiro, (författare)
University of Porto
Guénel, Pascal, (författare)
Centre for Research in Epidemiology and Population Health (CESP), University of Paris-Sud
Jöckel, Karl Heinz, (författare)
University Hospital Essen
Gonzalez, Agustin Llopis, (författare)
CIBER Epidemiology and Public Health (CIBERESP), Valencia University Hospital
Merletti, Franco, (författare)
University of Turin
Suárez-Varela, Maria Morales, (författare)
Valencia University Hospital, CIBER Epidemiology and Public Health (CIBERESP)
Trétarre, Brigitte, (författare)
Registre des Tumeurs de l'Hérault
Wingren, Gun, (författare)
Linköping University
Richiardi, Lorenzo, (författare)
University of Padova
Sabroe, Svend, (författare)
Aarhus University
Guenel, Pascal, (författare)
INSERM U1018, France; Univ Paris Sud, France
Joeckel, Karl-Heinz, (författare)
Univ Clin Essen, Germany
Llopis Gonzalez, Agustin, (författare)
Univ Valencia, Spain; CIBER Epidemiol and Salud Publ CIBERESP, Spain
Morales Suarez-Varela, Maria, (författare)
Univ Valencia, Spain; CIBER Epidemiol and Salud Publ CIBERESP, Spain
Tretarre, Brigitte, (författare)
Registre Tumeurs Herault, France
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Lunds universitet Onkologi och Patologi, Kampradlab. (creator_code:org_t)
Linköpings universitet Institutionen för klinisk och experimentell medicin. Avdelningen för neuro- och inflammationsvetenskap. (creator_code:org_t)
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Linköpings universitet Medicinska fakulteten. (creator_code:org_t)
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2019
Engelska 6 s.
Ingår i: Cancer Epidemiology. - Elsevier. - 1877-7821. ; 61, s. 133-138
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Purpose: Hardly anything is known about the aetiology of thymoma. This paper presents data regarding tobacco smoking and alcohol consumption in relation to thymoma from the first case-control study performed on this rare tumour. Methods: A European multi-centre case-control study including incident cases aged 35–69 years with thymoma between 1995 and 1997, was conducted in seven countries. A set of controls, used in seven parallel case-control studies by the same research group was used, including population-based controls from five countries and hospital controls with colon cancer from two countries. Altogether 103 cases, accepted by a reference pathologist, 712 colon cancer controls, and 2071 population controls were interviewed. Results: Tobacco smoking was moderately related with thymoma (OR 1.4, 95% CI 0.9–2.2), and a tendency to dose-response was shown (p = 0.04), with an increased risk for heavy smokers defined as ≥41 pack-years (OR 2.1, 95% CI 1.1–3.9). A high consumption of spirits defined as ≥25 g of alcohol per day was associated with an increased risk of thymoma (OR 2.4, 95% CI 1.1–5.4), whereas no association was found with beer or wine. Conclusions: Tobacco smoking and a high intake of spirits were indicated as risk factors for thymoma.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskaper -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Nyckelord

Alcohol
Case-control study
Risk factors
Thymoma
Thymus cancer
Tobacco smoking
Thymoma; Thymus cancer; Tobacco smoking; Alcohol; Risk factors; Case-control study

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