SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:lup.lub.lu.se:82a70347-6a4f-4917-a2b7-04a3336e4c6c"
 

Sökning: onr:"swepub:oai:lup.lub.lu.se:82a70347-6a4f-4917-a2b7-04a3336e4c6c" > Mid-Thigh Cortical ...

Mid-Thigh Cortical Bone Structural Parameters, Muscle Mass and Strength, and Association with Lower Limb Fractures in Older Men and Women (AGES-Reykjavik Study)

Johannesdottir, Fjola (författare)
Aspelund, Thor (författare)
Siggeirsdottir, Kristin (författare)
visa fler...
Jonsson, Brynjolfur (författare)
Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups
Mogensen, Brynjolfur (författare)
Sigurdsson, Sigurdur (författare)
Harris, Tamara B. (författare)
Gudnason, Vilmundur G. (författare)
Lang, Thomas F. (författare)
Sigurdsson, Gunnar (författare)
visa färre...
 (creator_code:org_t)
Springer, 2012
2012
Engelska.
Ingår i: Calcified Tissue International. - : Springer. - 1432-0827. ; 90:5, s. 354-364
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • In a cross-sectional study we investigated the relationship between muscle and bone parameters in the mid-thigh in older people using data from a single axial computed tomographic section through the mid-thigh. Additionally, we studied the association of these variables with incident low-trauma lower limb fractures. A total of 3,762 older individuals (1,838 men and 1,924 women), aged 66-96 years, participants in the AGES-Reykjavik study, were studied. The total cross-sectional muscular area and knee extensor strength declined with age similarly in both sexes. Muscle parameters correlated most strongly with cortical area and total shaft area (adjusted for age, height, and weight) but explained < 10 % of variability in those bone parameters. The increment in medullary area (MA) and buckling ratio (BR) with age was almost fourfold greater in women than men. The association between MA and muscle parameters was nonsignificant. During a median follow-up of 5.3 years, 113 women and 66 men sustained incident lower limb fractures. Small muscular area, low knee extensor strength, large MA, low cortical thickness, and high BR were significantly associated with fractures in both sexes. Our results show that bone and muscle loss proceed at different rates and with different gender patterns.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Ortopedi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Orthopedics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Nyckelord

Mid-thigh
Muscle-bone relationship
Aging
Fracture risk
CT

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy