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Early oral contraceptive use as a prognostic factor in breast cancer

Olsson, H., (författare)
Lunds universitet, Lund University, Medicinska fakulteten, Faculty of Medicine, Institutionen för kliniska vetenskaper, Lund, Department of Clinical Sciences, Lund, Tumörmikromiljö, Tumor microenvironment, Sektion I, Section I, Skåne University Hospital
Moller, T. R. (författare)
Ranstam, J., (författare)
Skåne University Hospital
visa fler...
Borg, A. (författare)
Ferno, M. (författare)
visa färre...
1988
Engelska.
Ingår i: Anticancer research. - International Institute of Cancer Research. - 0250-7005. ; 8:1, s. 29-32
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • The survival of 193 premenopausal breast cancer patients was investigated in relation to their history of early use of oral contraceptives. The women were born in 1939 or later and diagnosed in the southern health care region of Sweden. Women, who had started their oral contraceptive use (OC-use) before 20 years of age had a significantly lower survival rate as compared with those who had never used OC and late users (p = 0.02 and = 0.04 respectively, generalized Wilcoxon test). For women who started OC-use between 20 to 25 years of age, a tendency for a shorter survival was seen in comparison with women who had never used OC (p = 0.18). For all patients simultaneously, the relative risk adjusted for age at diagnosis increased for earlier OC-start. When only stages II and III were considered in a stratified multivariate model, a signficantly elevated risk was seen for early users of OC irrespective of age or of adjuvant treatment given. The estrogen and progesterone receptor concentrations of the primary tumor were significantly lower among early users (p = 0.001 and p = 0.05 respectively).

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

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Av författaren/redakt...
Olsson, H.
Moller, T. R.
Ranstam, J.
Borg, A.
Ferno, M.
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MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
och Klinisk medicin
och Cancer och onkol ...
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Anticancer resea ...
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Lunds universitet

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