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Urinary bladder cancer treated with radical cystectomy: Perioperative parameters and early complications prospectively registered in a national population-based database

Jerlstrom, Tomas (författare)
Örebro University Hospital, Sweden
Gardmark, Truls (författare)
Dept Surg & Urol, Danderyd Hosp, Danderyd, Sweden,Danderyd Hospital, Sweden
Carringer, Malcolm (författare)
Region Örebro län,Department of Urology, Örebro University Hospital, Örebro, Sweden,Örebro University Hospital, Sweden
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Holmang, Sten (författare)
Dept Urol, Sahlgrens Univ Hosp, Gothenburg, Sweden,Sahlgrens University Hospital, Sweden
Liedberg, Fredrik (författare)
Lund University,Lunds universitet,Urologi, Malmö (Abrahamsson),Forskargrupper vid Lunds universitet,Urological research, Malmö,Lund University Research Groups,Dept Urol, Skåne Univ Hosp, Malmö, Sweden,Skåne University Hospital, Sweden
Hosseini, Abolfazl (författare)
Dept Mol Med & Surg, Urol Sect, Karolinska Inst, Stockholm, Sweden,Karolinska Institute, Sweden
Malmstrom, Per-Uno (författare)
Uppsala University, Sweden
Ljungberg, Borje (författare)
Norrlands University Hospital, Sweden
Hagberg, Oskar (författare)
Reg Canc Ctr South, Lund, Sweden,Regional Cancer Centre South, Lund, Sweden
Jahnson, Staffan (författare)
Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Urologiska kliniken i Östergötland
Jerlström, Tomas (författare)
Department of Urology, University Hospital, Örebro, Sweden
Holmäng, Sten (författare)
Malmström, Per-Uno (författare)
Uppsala universitet,Urologkirurgi,Dept Surg Sci, Uppsala Univ, Uppsala, Sweden
Ljungberg, Börje (författare)
Umeå universitet,Urologi och andrologi,Njurcancer,Dept Surg & Perioperat Sci Urol & Androl, Norrlands Univ Hosp, Umeå, Sweden
Gårdmark, Truls (författare)
Jerlstrom, T (författare)
Carringer, M (författare)
Ljungberg, B (författare)
Holmang, S (författare)
Malmstrom, PU (författare)
Jahnson, S (författare)
Hagberg, O (författare)
Gardmark, T (författare)
Karolinska Institutet
Hosseini, A (författare)
Liedberg, F (författare)
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London : Taylor & Francis, 2014
Ingår i: Scandinavian Journal of Urology. - London : Taylor & Francis. - 2168-1813 .- 2168-1805. ; 48:4, s. 334-340
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
  • Objective. Cystectomy combined with pelvic lymph-node dissection and urinary diversion entails high morbidity and mortality. Improvements are needed, and a first step is to collect information on the current situation. In 2011, this group took the initiative to start a population-based database in Sweden (population 9.5 million in 2011) with prospective registration of patients and complications until 90 days after cystectomy. This article reports findings from the first year of registration. Material and methods. Participation was voluntary, and data were reported by local urologists or research nurses. Perioperative parameters and early complications classified according to the modified Clavien system were registered, and selected variables of possible importance for complications were analysed by univariate and multivariate logistic regression. Results. During 2011, 285 (65%) of 435 cystectomies performed in Sweden were registered in the database, the majority reported by the seven academic centres. Median blood loss was 1000 ml, operating time 318 min, and length of hospital stay 15 days. Any complications were registered for 103 patients (36%). Clavien grades 1-2 and 3-5 were noted in 19% and 15%, respectively. Thirty-seven patients (13%) were reoperated on at least once. In logistic regression analysis elevated risk of complications was significantly associated with operating time exceeding 318 min in both univariate and multivariate analysis, and with age 76-89 years only in multivariate analysis. Conclusions. It was feasible to start a national population-based registry of radical cystectomies for bladder cancer. The evaluation of the first year shows an increased risk of complications in patients with longer operating time and higher age. The results agree with some previously published series but should be interpreted with caution considering the relatively low coverage, which is expected to be higher in the future.


MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)


bladder carcinoma
radical cystectomy
bladder carcinoma
Bladder carcinoma
bladder carcinoma; complications; radical cystectomy

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