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Sökning: onr:"swepub:oai:lup.lub.lu.se:e322302a-1e53-422e-9ab8-8573cc1d0ce3" > Contact Allergy to ...

Contact Allergy to Fragrance Mix II and Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde : A Retrospective Study by International Contact Dermatitis Research Group

Bruze, Magnus (författare)
Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
Ale, Iris (författare)
Hospital de Clínicas “Dr. Manuel Quintela”.,University of the Republic
Andersen, Klaus E. (författare)
Odense University Hospital,University of Southern Denmark
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Cannavó, Alicia (författare)
Hospital de Clínicas "José de San Martín",University of Buenos Aires
Diepgen, Thomas (författare)
Heidelberg University
Elsner, Peter (författare)
Universitätsklinikum Jena
Goh, Chee Leok (författare)
National Skin Centre
Gonçalo, Margarida (författare)
University of Coimbra,University Hospital of Coimbra
Goossens, An (författare)
University Hospitals Leuven
McFadden, John (författare)
St John's Institute of Dermatology,St Thomas' Hospital
Nixon, Rosemary (författare)
Skin and Cancer Foundation Australia
Puangpet, Pailin (författare)
Institute of Dermatology Thailand
Sasseville, Denis (författare)
McGill University Health Center,McGill University Health Centre, Montreal General Hospital
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 (creator_code:org_t)
 
Lippincott Williams & Wilkins, 2020
2020
Engelska 4 s.
Ingår i: Dermatitis : contact, atopic, occupational, drug. - : Lippincott Williams & Wilkins. - 1710-3568. ; 31:4, s. 268-271
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • BACKGROUND: Fragrance mix II (FM II) is included in the baseline patch test series recommended by the International Contact Dermatitis Research Group (ICDRG). Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) is the most important sensitizer of the 6 fragrance materials included in FM II. Besides being a part of FM II, HICC is also tested separately in the ICDRG baseline series. OBJECTIVES: The aim of the study was to investigate the prevalence of contact allergy to FM II and HICC in 2012-2016 with a focus on simultaneous reactions and the percentage of missed contact allergy to HICC provided that only FM II had been tested. PATIENTS AND METHODS: A total of 25,019 consecutive dermatitis patients in 13 dermatology clinics representing 12 countries in 5 continents were patch tested with FM II and HICC in the baseline series. RESULTS: Contact allergy to FM II and HICC was found in 3.9% and 1.6%, respectively. For FM II, the frequency varied from 1.5% to 7.6% in different centers. The corresponding range for HICC was 0.2% to 3.6%. Simultaneous contact allergy to FM II and HICC was noted in 1.4% with the range 0.2% to 2.6%. Seventy-seven patients (0.31%) with contact allergy to HICC did not test positively to FM II. The range for missed HICC allergy by testing only FM II in the different centers would be 0.04% to 0.74%. The ratio between the contact allergy rates for FM II and HICC was similar for all centers, except for Montreal having significantly more contact allergy to FM II than to HICC. CONCLUSIONS: The frequency of missed contact allergy to HICC when testing only with FM II was less than 0.5%, therefore questioning the need to test HICC separately in the ICDRG baseline series.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

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