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BDNF DNA methylatio...
BDNF DNA methylation changes as a biomarker of psychiatric disorders : literature review and open access database analysis
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- Zheleznyakova, Galina Y. (författare)
- Karolinska Institutet,Uppsala universitet,Funktionell farmakologi,Karolinska Inst, Karolinska Univ Hosp, Dept Clin Neurosci, CMM L8-04, S-17176 Stockholm, Sweden.
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- Cao, Hao (författare)
- Uppsala universitet,Funktionell farmakologi
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- Schiöth, Helgi B. (författare)
- Uppsala universitet,Funktionell farmakologi
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(creator_code:org_t)
- 2016-06-06
- 2016
- Engelska.
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Ingår i: Behavioral and Brain Functions. - : Springer Science and Business Media LLC. - 1744-9081. ; 12
- Relaterad länk:
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https://uu.diva-port... (primary) (Raw object)
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visa fler...
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https://behavioralan...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Brain-derived neurotrophic factor (BDNF) plays an important role in nervous system development and function and it is well established that BDNF is involved in the pathogenesis of a wide range of psychiatric disorders. Recently, numerous studies have associated the DNA methylation level of BDNF promoters with certain psychiatric phenotypes. In this review, we summarize data from current literature as well as from our own analysis with respect to the correlation of BDNF methylation changes with psychiatric disorders and address questions about whether DNA methylation related to the BDNF can be useful as biomarker for specific neuropsychiatric disorders.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- BDNF
- DNA methylation
- Biomarkers
- Psychiatric disorders
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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