| 1. |
- Ljung, Patric, 1968-, et al.
(författare)
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Full Body Virtual Autopsies Using A State-of-the-art Volume Rendering Pipeline
- 2006
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Ingår i: IEEE Transactions on Visualization and Computer Graphics. - 1077-2626 .- 1941-0506. ; 12:5, s. 869-876
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- This paper presents a procedure for virtual autopsies based on interactive 3D visualizations of large scale, high resolutiondata from CT-scans of human cadavers. The procedure is described using examples from forensic medicine and the added valueand future potential of virtual autopsies is shown from a medical and forensic perspective. Based on the technical demands ofthe procedure state-of-the-art volume rendering techniques are applied and refined to enable real-time, full body virtual autopsiesinvolving gigabyte sized data on standard GPUs. The techniques applied include transfer function based data reduction using levelof-detail selection and multi-resolution rendering techniques. The paper also describes a data management component for large,out-of-core data sets and an extension to the GPU-based raycaster for efficient dual TF rendering. Detailed benchmarks of thepipeline are presented using data sets from forensic cases.
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| 2. |
- Lundström, Claes, 1973-, et al.
(författare)
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The alpha-histogram: Using Spatial Coherence to Enhance Histograms and Transfer Function Design
- 2006
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Ingår i: Proceedings Eurographics/IEEE Symposium on Visualization 2006, Lisbon, Portugal. ; , s. 227-234
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The high complexity of Transfer Function (TF) design is a major obstacle to widespread routine use of Direct Volume Rendering, particularly in the case of medical imaging. Both manual and automatic TF design schemes would benefit greatly from a fast and simple method for detection of tissue value ranges. To this end, we introduce the a-histogram, an enhancement that amplifies ranges corresponding to spatially coherent materials. The properties of the a-histogram have been explored for synthetic data sets and then successfully used to detect vessels in 20 Magnetic Resonance angiographies, proving the potential of this approach as a fast and simple technique for histogram enhancement in general and for TF construction in particular.
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| 3. |
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| 4. |
- Bahar, Bahram, et al.
(författare)
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Developing A-GPS as a Student Project
- 2006
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Rapport (populärvet., debatt m.m.)abstract
- The project consists of ten fourth-year computer science students at Uppsala University developing an A-GPS (Assisted-GPS) system. During the fall term of 2005 the students have developed a module for GPS-calculations in a GSM-network and an application that demonstrates a possible way of using the calculations module. This paper describes the design, the development process and the results of the project.
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| 6. |
- Bivall Persson, Petter, 1979-, et al.
(författare)
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Evaluating the Effectiveness of Haptic Visualization in Biomolecular Education - Feeling Molecular Specificity in a Docking Task
- 2006
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Ingår i: 12th IOSTE Symposium. - : Universiti Science Malaysia. - 9832700396 ; , s. 745-752
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Konferensbidrag (refereegranskat)abstract
- Within the molecular life sciences extensive use is made of visual representations, ranging from sketches to advanced computer graphics, often used to convey abstract knowledge that is difficult for the student to grasp. This work evaluates a new visual and haptic (tactile/kinetic) tool for protein docking in an in situ learning situation by combining qualitative and quantitative methods, performing tests and interviews with students; all aiming at a proper inclusion of visualization tools into biomolecular education. Preliminary results indicate time gains, strong positive affective responses and learning gains from the tasks, however the influence of haptics needs further investigation.
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| 7. |
- Borg, O Anders, et al.
(författare)
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Photochemistry of bromofluorobenzenes.
- 2006
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Ingår i: J Phys Chem A Mol Spectrosc Kinet Environ Gen Theory. - 1089-5639. ; 110, s. 7045-
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Tidskriftsartikel (refereegranskat)
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| 8. |
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| 9. |
- Bresell, Anders, et al.
(författare)
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Ontology annotation treebrowser: an interactive tool where the complementarity of medical subject headings and gene ontology improves the interpretation of gene lists
- 2006
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Ingår i: Applied Bioinformatics. - 1175-5636. ; 5:4, s. 225-236
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Tidskriftsartikel (refereegranskat)abstract
- Gene expression and proteomics analysis allow the investigation of thousands of biomolecules in parallel. This results in a long list of interesting genes or proteins and a list of annotation terms in the order of thousands. It is not a trivial task to understand such a gene list and it would require extensive efforts to bring together the overwhelming amounts of associated information from the literature and databases. Thus, it is evident that we need ways of condensing and filtering this information. An excellent way to represent knowledge is to use ontologies, where it is possible to group genes or terms with overlapping context, rather than studying one-dimensional lists of keywords. Therefore, we have built the ontology annotation treebrowser (OAT) to represent, condense, filter and summarise the knowledge associated with a list of genes or proteins. The OAT system consists of two disjointed parts; a MySQL® database named OATdb, and a treebrowser engine that is implemented as a web interface. The OAT system is implemented using Perl scripts on an Apache web server and the gene, ontology and annotation data is stored in a relational MySQL® database. In OAT, we have harmonized the two ontologies of medical subject headings (MeSH) and gene ontology (GO), to enable us to use knowledge both from the literature and the annotation projects in the same tool. OAT includes multiple gene identifier sets, which are merged internally in the OAT database. We have also generated novel MeSH annotations by mapping accession numbers to MEDLINE entries. The ontology browser OAT was created to facilitate the analysis of gene lists. It can be browsed dynamically, so that a scientist can interact with the data and govern the outcome. Test statistics show which branches are enriched. We also show that the two ontologies complement each other, with surprisingly low overlap, by mapping annotations to the Unified Medical Language System®. We have developed a novel interactive annotation browser that is the first to incorporate both MeSH and GO for improved interpretation of gene lists. With OAT, we illustrate the benefits of combining MeSH and GO for understanding gene lists. OAT is available as a public web service at: http://www.ifm.liu.se/bioinfo/oat
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