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- Abdel-Rehim, Mohamed
(författare)
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Microextraction by packed sorbent (MEPS) : A tutorial
- 2011
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Ingår i: Analytica Chimica Acta. - : Elsevier BV. - 0003-2670 .- 1873-4324. ; 701:2, s. 119-128
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Tidskriftsartikel (refereegranskat)abstract
- This tutorial provides an overview on a new technique for sample preparation, microextraction by packed sorbent (MEPS). Not only the automation process by MEPS is the advantage but also the much smaller volumes of the samples, solvents and dead volumes in the system. Other significant advantages such as the speed and the simplicity of the sample preparation process are provided. In this tutorial the main concepts of MEPS will be elucidated. Different practical aspects in MEPS are addressed. The factors affecting MEPS performance will be discussed. The application of MEPS in clinical and pre-clinical studies for quantification of drugs and metabolites in blood, plasma and urine will be provided. A comparison between MEPS and other extraction techniques such as SPE, LLE, SPME and SBSE will be discussed. (C) 2011 Elsevier B.V. All rights reserved.
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| 2. |
- Abdel-Rehim, Mohamed
(författare)
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On-Line Whole Blood Analysis Using Microextraction by Packed Sorbent and LC-MS-MS
- 2011
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Ingår i: LC GC North America. - 1527-5949 .- 1939-1889. ; 29:7, s. 612-618
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Tidskriftsartikel (refereegranskat)abstract
- Microextraction by packed sorbent (MEPS) is a new technique for sample preparation that can be connected on-line with liquid chromatography (LC) or gas chromatography (GC) systems without any modifications. This article describes the use of MEPS in clinical and preclinical studies to quantify different drugs in whole blood samples. MEPS was used to determine cyclophosphamide in mouse blood from preclinical g studies using 20 mu L of blood samples. The interday accuracies and 0 precisions ranged from 107-109% and from 2.0-7.0%, respectively. The determination of four immunosuppressive drugs in human blood by MEPS and liquid chromatography-mass spectrometry (LC-MS) is described. The method showed a good selectivity and sensitivity. The calibration curves for everolimus, sirolimus, and tacrolimus ranged from 0.5 to 50 ng/mL and for cyclosporine from 3.0 to 1500 ng/mL. Intraday precisions for the studied immunosuppressive drugs were 2.0-11.7% and interday precision ranged from 5.1 to 13.7% (CV).
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| 3. |
- Abdollahi, Kamran, et al.
(författare)
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Improving Performance of On Demand Multicast Routing by deleting lost join query packet
- 2010
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Ingår i: Proceedings of The Sixth Advanced International Conference on Telecommunications - AICT 2010. - : IEEE conference proceedings. - 9780769540214 ; , s. 316-322
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Konferensbidrag (refereegranskat)abstract
- A Mobile ad hoc network is a collection of wireless nodes that dynamically organize themselves to form a network without the need for any fixed infrastructure or centralized administration. The network topology dynamically changes frequently in an unpredictable manner since nodes are free to move. Support for multicasting is essential in such environment as it is considered to be an efficient way to deliver information from source nodes to many client nodes. A problem with multicast routing algorithms is their efficiency as their forwarding structure determines the overall network resource consumption makes them significantly less efficient than unicast routing algorithms. In this research, we improve the performance of the popular ODMRP multicast routing protocol by restricting the domain of join query packets, which have been lost. This is achieved by augmenting the join query packets with minimum extra information (one field), which denotes the number of the visited node from previous forwarding group. Simulation results show, that our mechanisms significantly reduce the control traffic and thus the overall latency and power consumption in the network.
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| 4. |
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| 5. |
- Abraham, Getahun Yacob
(författare)
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Education for Democracy? : Life Orientation: Lessons on Leadeship Qualities and Voting in South African Comprehensive Schools
- 2010
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This study takes as its starting point how teachers understand, interpret and teach social development aspects of Life Orientation in South African comprehensive schools. The specific focus is on lessons on leadership qualities and voting for third grade learners in four schools, each dominated by either Black, Coloured, White or mixed groups of learners. Field work with an ethnographic approach and a qualitative strategy was used to gain access to empirical data. Policy and curriculum documents, guidelines and textbooks were used. Classroom observations in four classes and interviews with 14 third grade teachers were conducted. Theoretical concepts of construction, deconstruction and reconstruction are applied. Ulf P Lundgren’s Frame Factor Theory is used to study school organization. Basil Bernstein’s Pedagogical Devices are considered when examining the different levels of pedagogical activities. To be a teacher in South Africa one needs to attend at least two years of teacher education after completing high school. Teachers in the classes studied underwent their teacher education during apartheid years. Due to limited in-service training, they sometimes experience problems of understanding and interpreting the learning area, which they usually tackle by consulting documents, colleagues or school authorities. The learners’ understanding varied based on their family background and type of school they attended. There were enormous differences in material, financial and organisational resources between classes and schools. The resources for teaching leadership qualities and voting were not, however, different between the classes. The lessons were teacher dominated and direct transmission was used as a method. The way teachers facilitated the lesson on leadership qualities and voting varied but all showed some democratic shortcomings. Apart from answering questions, learners were neither invited nor encouraged to participate to further their understanding of the theme. Limited aspects of leadership qualities were discussed, individual leaders’ roles were emphasised and the teachers picked candidates for class leaders in three of the classes. It was also evident that the class environments were not suitable for critical or creative thinking and democratic upbringing. The schools reproduced norms, values, languages and cultures of the different groups. Officially, teachers emphasised the common national South African identity. This emphasis on national identity could disguise the injustice some groups experience in society.
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| 6. |
- Abraham, Getahun Yacob
(författare)
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Lektioner om ledarskapskvalitet och röstningsförfarande i sydafrikanska grundskolor
- 2011
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Ingår i: Kapet (avslutad tryckt version). - Karlstad : Karlstads universitet. - 1653-4743. ; 1:1, s. 96-107
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Denna studie tar sin utgångspunkt i hur lärare undervisar om den sociala utvecklingsdelen av ”Life Orientation” i sydafrikanska grundskolan. Specifikt fokus ligger på lektioner om ledarskapskvalitet och om att rösta för tredjeklasselever i fyra skolor. Var och en av klasserna dominerades av antingen svarta, färgade, vita eller blandade grupper av elever. Ulf P Lundgrens ramfaktorteori användes för att studera skolans organisation. Basil Bernsteins ”Pedagogic device” användes för att förstå olika pedagogiska verksamheter i klassrummet. Fältarbeten med en etnografisk metod och en kvalitativ strategi användes för att få tillgång till empiriska data. Policy- och läroplansdokument, riktlinjer och läroböcker analyserades. Klassrumsobservationer i fyra klasser och intervjuer med 14 tredjeklasslärare genomfördes. För att vara lärare i Sydafrika krävs minst två års lärarutbildning efter avslutad gymnasieskola. Lärarna i de klasser som studerades genomgick sin lärarutbildning under apartheidtiden. På grund av begränsad fortbildning och bristande erfarenheter av den nya läroplanen hade de ibland svårigheter att förstå och tolka det aktuella ämnet. Enorma skillnader i material, ekonomiska och organisatoriska resurser förelåg mellan olika klasser och skolor. Lärarna dominerade lektionerna och direkt överföring användes som metod. Det sätt lärarna höll lektion om ledaregenskap och om att rösta varierade, men alla visade demokratiska brister. Lärarna valde själva kandidater till klassledare i tre av klasserna. Det blev också tydligt att klassernas miljöer inte befrämjade vare sig kritiskt och kreativt tänkande eller demokratisk fostran.
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| 9. |
- Abrahamsen Grøndahl, Vigdis, 1964-, et al.
(författare)
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Quality of care from patients' perspective : impact of the combination of person-related and external objective care conditions
- 2011
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Ingår i: Journal of Clinical Nursing. - : Wiley. - 0962-1067 .- 1365-2702. ; 20:17/18, s. 2540-2551
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Tidskriftsartikel (refereegranskat)abstract
- Aims and objectives. To describe patients' perceptions of quality of care and to explore combinations of person-related and external objective care conditions as potential predictors of these perceptions. Background. Several studies have examined various single factors of person-related and external objective care conditions in relation to quality of care. None of these has included the effect of over-occupancy on patients' perception of quality of care. Furthermore, little is known about how combinations of different factors are related to each other and to the perception of quality of care using multivariate analysis. Design. A cross-sectional design. Method. A total of 528 patients (83·7%) from 12 medical, surgical or medical-surgical wards in five hospitals in Norway participated. Perceptions of quality of care and person-related conditions were measured with the 'Quality from Patient's Perspective' instrument. Data on external objective care conditions was collected from ward statistics provided by head nurses. Multivariate general linear modelling was used ( p < 0·05). Results. The combination of person-related and external objective care conditions revealed five factors that predict patients' perception of quality of care. Three of these are person-related conditions: sex, age and self-reported psychological well-being and two of them are external objective care conditions: RNs (headcount) on the wards and frequency of over-occupancy. These five factors explained 55% of the model. Patients rated the quality of care high. Conclusions. Sex, age, psychological well-being, frequency of over-occupancy and the number of RNs are important factors that must be emphasised if patients are to perceive the quality of care as high. Relevance to clinical practice. Head nurses and healthcare authorities must continually prepare the wards for over-occupancy and they must consider the number of RNs working on the wards.
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| 10. |
- Abrahamsson, Lena, et al.
(författare)
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Från bergets djup till sjunde himlen
- 2010
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Ingår i: Arbetsmarknad & Arbetsliv. - Karlstad : Karlstads universitet. - 1400-9692 .- 2002-343X. ; 16:4, s. 11-29
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Tidskriftsartikel (refereegranskat)abstract
- I Kirunagruvan kan vi under en period på 50 år följa förändringen av produktionsarbetet från ett tungt och farligt underjordsarbete till fjärrstyrning via modern teknik i en trygg kontorsmiljö. Syftet med artikeln är att reflektera över en kunskapsförvandling från äldre tiders hantverkskunnande med kroppsliga och tysta kunskaper till något nytt. I artikeln diskuterar vi hur individ och organisation skapar och återskapar kvalifikationer, identiteter och kön i mötet med ny teknik och nya organisationsformer.
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