| 1. |
- Kanmert, Daniel, et al.
(författare)
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IgG Rheumatoid Factors Against the Four Human Fc-gamma Subclasses in Early Rheumatoid Arthritis (The Swedish TIRA Project)
- 2012
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Ingår i: Scandinavian Journal of Immunology. - : Blackwell Publishing. - 0300-9475 .- 1365-3083. ; 75:1, s. 115-119
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Tidskriftsartikel (refereegranskat)abstract
- Rheumatoid factor (RF), i.e. a family of autoantibodies against the Fc part of IgG, is an important seromarker of rheumatoid arthritis (RA). Traditional particle agglutination without disclosing the antibody isotype remains the predominating diagnostic method in clinical routine. Although IgG-RF attracts pathogenic interest, its detection remains technically challenging. The present study aimed at developing a set of tests identifying IgG-RFs directed against the four IgG subclasses. IgG-RF against either subclass of human IgG-Fc were analysed with four novel enzyme-linked immunosorbent assays (ELISAs) utilizing four recombinant human Fc-gamma fragments (hIgG14) as sources of antigen. Sera from 40 patients with recent onset RA (20 seropositive and 20 seronegative by IgM-RF and IgA-RF-isotype-specific ELISA) were analysed. Sera from 20 healthy blood donors served as reference. Among the IgM-/IgA-RF-positive RA-sera, IgG-RF was found directed against hIgG1 and hIgG2, but not against hIgG3 or hIgG4. Significant correlations were seen between IgG-RF against hIgG2-Fc and IgM-RF (r = 0.666) levels. Further prospective studies are warranted to elucidate any correlation to disease course and outcome.
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| 2. |
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| 3. |
- Smith, Christian, 1975-, et al.
(författare)
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Optimal Command Ordering for Serial Link Manipulators
- 2012
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Ingår i: 2012 12th IEEE-RAS International Conference on Humanoid Robots (Humanoids). - : IEEE Robotics and Automation Society. - 9781467313698 ; , s. 255-261
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Konferensbidrag (refereegranskat)abstract
- Reducing the number of cables needed for the actuators and sensors of humanoid and other robots with high numbers of degrees of freedom (DoF) is a relevant problem, often solved by using a common bus for all communication, which may result in bandwidth limitation problems. This paper proposes an optimized method to re-order the commands sent to the joint-local controllers of a high DoF serial manipulator. The proposed method evaluates which local controller would benefit the most from an updated command given a cost function, and sends a command to this controller. As is demonstrated in both simulation and in experiments on a real robot, the resulting scheme can significantly improve system performance, equivalent to increasing the communication frequency by up to 3 times.
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| 4. |
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| 5. |
- Marner, Anders, 1949-
(författare)
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Kreativitet och bildundervisning
- 2000
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Ingår i: Tidskrift för lärarutbildning och forskning. - Umeå : Fakultetsnämnden för lärarutbildning, Umeå universitet. - 1404-7659. ; 7:2/3, s. 103-114
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Tidskriftsartikel (refereegranskat)
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| 6. |
- Tuomainen, Marjo, et al.
(författare)
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Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET)
- 2019
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Ingår i: American Journal of Clinical Nutrition. - : OXFORD UNIV PRESS. - 0002-9165 .- 1938-3207. ; 110:5, s. 1108-1118
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Tidskriftsartikel (refereegranskat)abstract
- Background: Recently, a group of betainized compounds have been suggested to play a role in health effects in relation to a whole-grain-rich diet.Objectives: The aims of this study were to develop a quantitative mass spectrometric method for selected betainized compounds in human plasma, and to investigate their association with nutrient intake and measures of metabolic health in participants of the SYSDIET study.Methods: The SYSDIET study was a controlled randomized intervention including individuals with metabolic syndrome, where the healthy Nordic diet (HND) group increased intakes of whole grains, canola oil, berries, and fish, whereas the control diet (CD) group consumed low-fiber cereal products, milk fat, and restricted amounts of fish and berries. A quantitative LC combined with triple quadrupole MS method for betainized compounds was developed and applied to fasting plasma samples from baseline (week 0) and the end of the intervention (week 18 or 24). Concentrations of betainized compounds were correlated with intakes of selected nutrients and fiber and measures of metabolic health.Results: Pipecolic acid betaine (PAB) concentrations were significantly higher in the HND group than in the CD group (P = 0.00032) at the end of the intervention and correlated directly (P < 0.0001) with intakes of dietary fiber (r = 0.376) and a biomarker related to whole-grain rye intake, namely the ratio of alkylresorcinol C17:0 to C21:0 (r = 0.442). PAB was associated inversely with fasting plasma insulin consistently at the beginning and at the end of the intervention (P < 0.001, r = -0.300; P < 0.01, r = -0.250, respectively), as well as IL-1 receptor antagonist (P < 0.01, r = -0.232 at the beginning; P < 0.01, r = -0.236 at the end) and serum LDL/HDL cholesterol (P < 0.01, r = -0.239 at the beginning; P < 0.01, r = -0.241 at the end).Conclusions: Among adults with the metabolic syndrome, PAB plasma concentrations were associated with fasting insulin, inflammation, and lipids and were significantly increased with adoption of the HND. Further studies are needed to clarify the biological functions of betainized compounds.
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| 7. |
- Lawal, Najeem, et al.
(författare)
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Power Consumption Measurement & Configuration Time of FPGA
- 2015
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Ingår i: 2015 POWER GENERATION SYSTEMS AND RENEWABLE ENERGY TECHNOLOGIES (PGSRET-2015). - 9781467368131 - 9781467368124 ; , s. 63-67
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Konferensbidrag (refereegranskat)abstract
- In this paper, we presents results concerning power consumption and configuration time for FPGA. FPGAs re-programmability, flexibility and re-configurability give rise to number of possibilities like adding more and more features, increasing lifetime duration to embedded systems. Power consumption of the peripheral devices is also meaningfully affects by Time behavior. Estimation based on average activity may not being useful for accurate power estimation of system. The configuration time of FPGA depend on configuration data width, size file, clock frequency and flash time access. We measured the total power consumption on each voltage supply and the total configuration time of Spartan-6 FPGA Atlys board using LabVIEW. Comparison had been made between estimated power value and measured power value. Hence, we believe that our experiment results will be useful to other FPGA-based embedded systems.
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| 8. |
- Lu, Ru-Sen, et al.
(författare)
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Detection of Intrinsic Source Structure at similar to 3 Schwarzschild Radii with Millimeter-VLBI Observations of SAGITTARIUS A*
- 2018
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 1538-4357 .- 0004-637X. ; 859:1
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Tidskriftsartikel (refereegranskat)abstract
- We report results from very long baseline interferometric (VLBI) observations of the supermassive black hole in the Galactic center, Sgr A*, at 1.3 mm (230 GHz). The observations were performed in 2013 March using six VLBI stations in Hawaii, California, Arizona, and Chile. Compared to earlier observations, the addition of the APEX telescope in Chile almost doubles the longest baseline length in the array, provides additional uv coverage in the N-S direction, and leads to a spatial resolution of similar to 30 mu as (similar to 3 Schwarzschild radii) for Sgr A*. The source is detected even at the longest baselines with visibility amplitudes of similar to 4%-13% of the total flux density. We argue that such flux densities cannot result from interstellar refractive scattering alone, but indicate the presence of compact intrinsic source structure on scales of similar to 3 Schwarzschild radii. The measured nonzero closure phases rule out point-symmetric emission. We discuss our results in the context of simple geometric models that capture the basic characteristics and brightness distributions of disk-and jet-dominated models and show that both can reproduce the observed data. Common to these models are the brightness asymmetry, the orientation, and characteristic sizes, which are comparable to the expected size of the black hole shadow. Future 1.3 mm VLBI observations with an expanded array and better sensitivity will allow more detailed imaging of the horizon-scale structure and bear the potential for a deep insight into the physical processes at the black hole boundary.
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| 9. |
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| 10. |
- Berndt, Jaqueline, Prof Dr, 1963-
(författare)
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Kusazōshi as Comic Books? Reading Early Modern Graphic Narratives from a Manga Studies Perspective
- 2024
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Ingår i: Graphic Narratives from Early Modern Japan. - Leiden : Brill Academic Publishers. - 9789004504103 ; , s. 530-559
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- This chapter puts conceptualizations of kuzazōshi as “comic books” to the test by subjecting two early modern graphic narratives to a mangaesque reading, that is to say, a reading that treats them as if they were contemporary story-manga. However, this reading does not foreground character types, narrative tropes, visual motifs, or parodic intertextuality, which normally are the subject of investigation by literary scholars; preference is given to embodied reading, to the perceptual rather than cognitive effects of the forms at hand. This includes intermedial considerations, in particular regarding the argument that the storytelling of modern comics is fundamentally informed by cinema. The manga-informed readings foreground two central issues: on the one hand, the perceptual movement of the gaze which connects to page-turns as movements of the hand, and the narrative’s visual flow forward; on the other hand, the representation of characters’ feelings, which in turn may move the reader and lead to empathetic engagement. In conclusion, the contingency of the notion of “manga” comes to the fore, and the conceptualization of kusazōshi as “comic books” appears as a matter of degree, depending on the considered historical periods, genres, and works of manga, and also the aesthetic aspects that are highlighted. Rendered in still, mute, and monochrome fragmented drawings, both kusazōshi and (print-based) story-manga afford an agency to their readers, that differs from both classic live-action film and recent (vertical-scroll) webtoons. To trace this agency, it is vital to consider the perceptual, sensory, and cognitive effects of the material forms at hand, and their embodied reading.
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