SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Andersson Irene) srt2:(1995-1999)"

Sökning: WFRF:(Andersson Irene) > (1995-1999)

  • Resultat 1-6 av 6
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  •  
3.
  • Andersson, Roger, et al. (författare)
  • Etnisk boendesegregation i teori och praktik
  • 1996
  • Ingår i: SOU 1996:55, Vägar in i Sverige. - : Stockholm: Fritze. ; , s. 155-204
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
  •  
4.
  •  
5.
  •  
6.
  • Schmekel, Birgitta, 1945-, et al. (författare)
  • Stereoselective pharmacokinetics of S-salbutamol after administration of the racemate in healthy volunteers
  • 1999
  • Ingår i: European Respiratory Journal. - 0903-1936 .- 1399-3003. ; 13:6, s. 1230-1235
  • Tidskriftsartikel (refereegranskat)abstract
    • Racemic R,S-salbutamol is taken to relieve bronchial constriction. Only the R-enantiomer has bronchodilating properties. The S-enantiomer has been proposed to cause in vitro bronchial hyperreactivity in guinea-pigs. Stereoselective elimination of salbutamol has been shown, with S-salbutamol being eliminated at a slower rate than R-salbutamol. This study questioned whether rates of stereoselective elimination were similar after oral or lung delivery, and whether the S:R ratio would increase after repeated inhalations in a situation resembling a common clinical use. Eighteen healthy volunteers received single-dose racemic salbutamol as a solution instilled in the trachea during anaesthesia, as inhaled micronized powder and/or as ingested tablets. Five volunteers inhaled repeated doses of racemic salbutamol. Concentrations in plasma and urine were measured using a technique which allowed chiral separation of samples with concentrations as low as 0.1 ng·mL -1. The bioavailability of S-salbutamol was significantly higher than that of R-salbutamol after the different modes of administration. Stereoselective elimination was more pronounced after oral administration than after inhalation. Repeated inhalations resulted in successive increases in the S:R ratio as steady state was approached. In conclusion, the clinical consequences of increasing plasma concentrations of S-salbutamol need to be further assessed.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-6 av 6

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy