| 1. |
- Ali Kamyabi, Mohammad, et al.
(författare)
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A high-performance glucose biosensor using covalently immobilised glucose oxidase on a poly(2,6-diaminopyridine)/carbon nanotube electrode
- 2013
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Ingår i: Talanta. - : Elsevier. - 0039-9140 .- 1873-3573. ; 116, s. 801-808
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Tidskriftsartikel (refereegranskat)abstract
- A highly-sensitive glucose biosensor amenable to ultra-miniaturisation was fabricated by immobilisation of glucose oxidase (GOx), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWNT/GCE). Cyclic voltammetry was used for both the electrochemical synthesis of poly-(2,6-DP) on the surface of a MWNT-modified GC electrode, and characterisation of the polymers deposited on the GC electrode. The synergistic effect of the high active surface area of both the conducting polymer, i.e., poly-(2,6-DP) and MWNT gave rise to a remarkable improvement in the electrocatalytic properties of the biosensor. The transfer coefficient (alpha), heterogeneous electron transfer rate constant and Michaelis-Menten constant were calculated to be 0.6, 4 s(-1) and 0.20 mM at pH 7.4, respectively. The GOx/poly(2,6-DP)/MWNT/GC bioelectrode exhibited two linear responses to glucose in the concentration ranging from 0.42 mu M to 8.0 mM with a correlation coefficient of 0.95, sensitivity of 52.0 mu AmM-1 cm(-2), repeatability of 1.6% and long-term stability, which could make it a promising bioelectrode for precise detection of glucose in the biological samples. (C) 2013 Elsevier B.V. All rights reserved.
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| 2. |
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Bioengineered Nanomaterials
- 2013
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- "This book focuses on the novel methodologies and strategies adopted during recent research and development of bioengineered nanomaterials for biomedical applications. It provides comprehensive and updated information on developments in this emerging area. The chapters discuss topics such as nanoemulsions as a vaccine adjuvant, bio-ceramic nanomaterials in medical applications, the potential of nanoparticles for the treatment of solid tumors and metastasis, natural and synthetic nanoporous membranes for cell encapsulation therapy, silver nanoparticles, nanotoxcity testing and bioapplications, inorganic nanoparticle materials for controlled release of drugs, and more"--Provided by publisher.Many varieties of new, complex diseases are constantly being discovered, which leaves scientists with little choice but to embrace innovative methods for controlling the invasion of life-threatening problems. The use of nanotechnology has given scientists an opportunity to create nanomaterials that could help medical professionals in diagnosing and treating problems quickly and effectively. Bioengineered Nanomaterials presents in-depth information on bioengineered nanomaterials currently being developed in leading research laboratories around the world. In particular, the book focuses on nanom.
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| 3. |
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Biomedical materials and diagnostic devices
- 2012
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- "The functional materials with the most promising outlook have the ability to precisely adjust the biological phenomenon in a controlled mode. Engineering of advanced bio- materials has found striking applications in used for biomedical and diagnostic device applications, such as cell separation, stem-cell, drug delivery, hyperthermia, automated DNA extraction, gene targeting, resonance imaging, biosensors, tissue engineering and organ regeneration"--Provided by publisher.
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| 4. |
- Chey, Chan Oeurn, et al.
(författare)
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Impact of nanotoxicology towards technologists to end users
- 2013
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Ingår i: Advanced Materials Letters. - Allahabad, Uttar Pradesh , India : Vinova Bhave Research Institute. - 0976-3961 .- 0976-397X. ; 4:8, s. 591-597
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Tidskriftsartikel (refereegranskat)abstract
- The length scale for nanomaterial is small enough to be invisible and presume innocence for the initial avoidance of the toxicity issues. Again it was beyond the understanding of the time frame when nanotechnology just blooms that a length scale itself might be an important toxic parameter apart from its materialistic properties. We present this report to address the fundamental issues and questions related to the nanotoxicity issues from laboratory to the land of applications. We emphasize about the basic nanoscale materials that are regularly being used by the scientific community and the nanotechnology based materials that has already in the market or will come soon.
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| 5. |
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Integrated Biomaterials for Biomedical Technology
- 2012
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications. The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications.
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| 6. |
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Intelligent Nanomaterials : processes, properties, and applications
- 2012
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- The last three decades have seen extraordinary advances in the generation of new materials based on both fundamental elements and composites, driven by advances in synthetic chemistry and often drawing inspiration from nature. The concept of an intelligent material envisions additional functionality built into the molecular structure, such that a desirable response occurs under defined conditions.Divided into 4 parts: Inorganic Materials; Organic Materials; Composite Materials; and Biomaterials, the 22 chapters cover the latest research and developments in the processing, properties, and applications of intelligent nanomaterials. Included are molecular device materials, biomimetic materials, hybrid-type functionalized polymers-composite materials, information-and energy-transfer materials, as well as environmentally friendly materials.
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| 7. |
- Karimian, Najmeh, et al.
(författare)
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An ultrasensitive molecularly-imprinted human cardiac troponin sensor
- 2013
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Ingår i: Biosensors & bioelectronics. - : Elsevier. - 0956-5663 .- 1873-4235. ; 50, s. 492-498
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Tidskriftsartikel (refereegranskat)abstract
- Cardiac troponin T (TnT) is a highly sensitive cardiac biomarker for myocardial infarction. In this study, the fabrication and characterisation of a novel sensor for human TnT based on a molecularly-imprinted electrosynthesised polymer is reported. A TnT sensitive layer was prepared by electropolymerisation of o-phenylenediamine (o-PD) on a gold electrode in the presence of TnT as a template. To develop the molecularly imprinted polymer (MIP), the template molecules were removed from the modified electrode surface by washing with alkaline ethanol. Electrochemical methods were used to monitor the processes of electropolymerisation, template removal and binding. The imprinted layer was characterised by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and atomic force microscopy (AFM). The incubation of the MIP-modified electrode with respect to TnT concentration resulted in a suppression of the ferro/ferricyanide redox process. Experimental conditions were optimised and a linear relationship was observed between the peak current of [Fe(CN)(6)](3-)/[Fe (CN)(6)](4-) and the concentration of TnT in buffer over the range 0.009-0.8 ng/mL, with a detection limit of 9 pg/mL. The TnT MIP sensor was shown to have a high affinity to TnT in comparison with nonimprinted polymer (NIP) electrodes in both buffer and blood serum.
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| 8. |
- Karimian, N, et al.
(författare)
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On/off-switchable electrochemical sensor for folicacid based on molecularly imprinted technology.
- 2013
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Ingår i: Electrochemistry communications. - : Elsevier BV. - 1388-2481 .- 1873-1902. ; 36, s. 92-95
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Tidskriftsartikel (refereegranskat)abstract
- The combination of smart polymers with molecular imprinting offers a powerful tool to design more effective sensors and medical devices. In this study, a temperature sensitive amine-terminated poly(N-isopropylacrylamide) block with (N,N'-methylenebisacrylamide) cross-linker along with o-phenylenediamine was electropolymerised on a gold electrode in the presence of folic acid (FA) as template to produce an on/off-switchable molecularly imprinted polymer (MIP) affinity sensor for folic acid. Differential pulse voltammetry and cyclic voltammetry were used to characterise the FA-imprinted layer. Incubation of the MIP-modified electrode with FA resulted in a suppression of the ferro/ferricyanide redox process. The highest sensitivity of this temperature gated on/off-switchable folic acid sensor was achieved at 22 °C. Such switchable affinity materials offer considerable potential for the design of highly selective and controllable biosensors and immunoassays.
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| 9. |
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| 10. |
- Li, Songjun, et al.
(författare)
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‘On/off’-switchable catalysis by a smart enzyme-like imprinted polymer
- 2011
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Ingår i: Journal of Catalysis. - : Elsevier. - 0021-9517 .- 1090-2694. ; 278:2, s. 173-180
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Tidskriftsartikel (refereegranskat)abstract
- ‘On/off’-switchable catalysis by a smart enzyme-like imprinted polymer is reported. This unique imprinted polymer was composed of poly(N-isopropylacrylamide)-containing p-nitrophenyl phosphate-imprinted networks that exhibited temperature-dependent hydrophilicity/hydrophobicity. At a relatively low temperature (such as 20 °C), this polymer was capable of vigorous catalysis for the hydrolysis of p-nitrophenyl acetate due to its hydrophilic networks, which enabled access to the imprinted framework. On the contrary, at higher temperatures (such as 40 °C), this polymer demonstrated poor catalysis resulting from its dramatically increased hydrophobicity, which inhibited access to the imprinted sites. Unlike previously reported imprinted polymers which lack adjustable networks, this novel imprinted polymer employed thermosensitive poly(N-isopropylacrylamide) networks, thus enabling the switchable catalysis.
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