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  • Want, Elizabeth J, et al. (författare)
  • From exogenous to endogenous : the inevitable imprint of mass spectrometry in metabolomics.
  • 2007
  • Ingår i: Journal of Proteome Research. - : American Chemical Society (ACS). - 1535-3893 .- 1535-3907. ; 6:2, s. 459-68
  • Tidskriftsartikel (refereegranskat)abstract
    • Mass spectrometry (MS) is an established technology in drug metabolite analysis and is now expanding into endogenous metabolite research. Its utility derives from its wide dynamic range, reproducible quantitative analysis, and the ability to analyze biofluids with extreme molecular complexity. The aims of developing mass spectrometry for metabolomics range from understanding basic biochemistry to biomarker discovery and the structural characterization of physiologically important metabolites. In this review, we will discuss the techniques involved in this exciting area and the current and future applications of this field.
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  • Wang, Zhenkan, et al. (författare)
  • Ultra-high-speed PLIF imaging for simultaneous visualization of multiple species in turbulent flames
  • 2017
  • Ingår i: Optics Express. - 1094-4087. ; 25:24, s. 30214-30228
  • Tidskriftsartikel (refereegranskat)abstract
    • In order to obtain more detailed characteristics and information in highly turbulent flames, for a better understanding of the transient behavior of eddies in such flames, a measurement technique with sufficient temporal resolution is requested. However, the probing of species distributions relevant in combustion (e.g. OH, CH2O) with ultra-high-speed laser diagnostics still remains a challenge. Nd:YAG clusters commercially available can generate only 4-8 pulses, although with high laser energy. Systems based on a diode-pumped solid-state Nd:YAG laser combined with a dye laser produce only about 100 μJ pulse energy at ultra-high repetition rates (≥50 kHz). Even more comprehensive information on the flame structure can be gained if simultaneous recording of multi-species is performed. In the present work, the development of the first ultra-high-speed diagnostic technique capable of simultaneous probing of hydroxyl radicals and formaldehyde distributions at a repetition rate of 50 kHz is outlined. This has been achieved by employing a burst laser pumped optical parametric oscillator system for the simultaneous detection of CH2O excited at 355 nm and OH-radicals excited at 283 nm, where the interference of scattering laser light can be avoided. The applicability of the proposed technique was demonstrated in a highly turbulent jet flame. Moreover, the presented improvement in terms of the number of consecutive images recorded with ultra-high-speed planar laser induced fluorescence imaging is significant. Due to the high temporal resolution, the movement of CH2O pocket enclosed by OH at the flame tip can be clearly captured. The transport velocity of the CH2O pocket was calculated and found to be in good agreement with previous LDV results.
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  • Carrol, Gareth, et al. (författare)
  • Found in translation : the influence of the L1 on the reading of idioms in a L2
  • 2016
  • Ingår i: Studies in Second Language Acquisition. - 1470-1545. ; 38:3, s. 403-443
  • Tidskriftsartikel (refereegranskat)abstract
    • Formulaic language represents a challenge to even the most proficient of language learners. Evidence is mixed as to whether native and non-native speakers process it in a fundamentally different way, whether exposure can lead to more nativelike processing for non-natives, and how L1 knowledge is used to aid comprehension. In this study we investigate how advanced non-native speakers process idioms encountered in their L2. We use eye-tracking to see whether a highly proficient group of L1 Swedes show any evidence of formulaic processing for English idioms. We also compare translations of Swedish idioms and congruent idioms (items that exist in both languages) to see how L1 knowledge is utilised during online processing. Results support the view that L1 knowledge is automatically used from the earliest stages of processing, regardless of whether sequences are congruent, and that exposure and advanced proficiency can lead to nativelike formulaic processing in the L2.
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  • Odensten, Christoffer, et al. (författare)
  • Battle of the Bulge : a qualitative analysis of living with a parastomal hernia
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Background: Parastomal hernia (PSH) is a common complication of a colostomy. Approximately one third of patients have a PSH 3 to 5 years after surgery. There is much qualitative research into living with a stoma, less so when it comes to living with a PSH.Method: A qualitative study using semi-structured interviews. The participants were participants in a large randomised trial studying the effects of a prophylactic mesh when creating a colostomy. All participants were survivors of rectal cancer. Inductive content analysis was used for data processing. 17 heterogeneous informants (age, gender, geographical location) were interviewed based on a saturated selection.Results: A major theme was identified in the interviews; “patients coping with parastomal hernia.” In line with this we identified four core coping strategies; meaningfulness; knowledge-based coping; social-based coping; and problem-based coping. For each category further subcategories were identified. We found that a deep sense of gratitude, for survival rectal cancer impacted the informant’s perception on their general wellbeing. Furthermore, we found the paramount importance of stoma nurses, or similar health care workers, enabling the patient to overcome different problems with a PSH.Discussion: There is a need to better understand the patient’s perception of living with PSH and how to cope with this. The purpose is to ease the transition into living with a stoma, and perhaps a PSH. The coping strategies identified in this report may be incorporated into teaching and information material and also be used by nurses and doctors meeting patients.
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