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1.
  • 3D digital modelling in visual arts education
  • 2024
  • Editorial collection (other academic/artistic)abstract
    • The following 3D Digital Modelling in Visual Arts Education forms part of the Tilde seriesand is based on collaboration in a project involving Aalborg University and College University Copenhagen (Denmark), the University of Gothenburg and Umeå University (Sweden).The project’s aim was to explore the learning potential held by 3D sculpting for art teachersby identifying new image-making processes in modelling and sculpting. Another aim wasto integrate the project’s outcome in didactics and teaching activities for teacher educatorsin visual arts connected to the subject area.The project was fnanced by EDDA Norden during 2021 and several seminars werearranged to present research in the subject area visual arts, 3D modelling, and use of technology. The results may be of particular interest to a wider audience in the research felds ofvisual arts education, multimodal learning designs, and teacher education. The publicationis based on presentations made at Aalborg University in Copenhagen during the autumn of2021 and at a symposium called 3D-sculpting: A Nordic Higher Education CollaborationProject at the NERA conference held in Oslo in the spring of 2023. 
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2.
  • Abdelmalek, George, et al. (author)
  • Intercostal nerve transfer for biceps reinnervation in obstetrical brachial plexus palsy : a preferred reporting items for systematic reviews and meta-analysis for individual patient data systematic review using individualized fusion and comparison to supraclavicular exploration and nerve grafting
  • 2024
  • In: Journal of Children's Orthopaedics. - : Sage Publications. - 1863-2521 .- 1863-2548. ; 18:1, s. 54-63
  • Research review (peer-reviewed)abstract
    • Introduction: The objective of this study was to search existing literature on nerve reconstruction surgery in patients with obstetric brachial plexus palsy to determine whether treatment with supraclavicular exploration and nerve grafting produced better elbow flexion outcomes compared to intercostal nerve transfer.Methods: This study was a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis for Individual Patient Data guidelines. A systematic search was conducted using multiple databases. An ordinal regression model was used to analyze the effect of using supraclavicular exploration and nerve grafting or intercostal nerve on elbow flexion with the two scores measured: elbow flexion Medical Research Council scores and Toronto active movements scale scores for elbow flexion.Results: A final patient database from 6 published articles consisted of 83 supraclavicular exploration and nerve grafting patients (73 patients with Medical Research Council and 10 patients with Toronto score) and 7 published articles which consisted of 131 intercostal nerve patients (84 patients with Medical Research Council and 47 patients with Toronto scores). Patients who underwent supraclavicular exploration and nerve grafting presented with an average Medical Research Council score of 3.9 ± 0.72 and an average Toronto score of 6.2 ± 2.2. Patients who underwent intercostal nerve transfer presented with an average Medical Research Council score of 3.9 ± 0.71 and an average Toronto score of 6.4 ± 1.2. There was no statistical difference between supraclavicular exploration and nerve grafting and intercostal nerve transfer when utilizing Medical Research Council elbow flexion scores (ordinal regression: 0.3821, standard error: 0.4590, p = 0.2551) or Toronto Active Movement Scale score for elbow flexion (ordinal regression: 0.7154, standard error: 0.8487, p = 0.2188).Conclusion: Regardless of surgical intervention utilized (supraclavicular exploration and nerve grafting or intercostal nerve transfers), patients had excellent outcomes for elbow flexion following obstetric brachial plexus palsy when utilizing Medical Research Council or Toronto scores for elbow flexion. The difference between these scores was not statistically significant.Type of study/Level of evidence: Therapeutic Study: Investigating the Result of Treatment/level III.
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3.
  • Abi Saad, Elie, et al. (author)
  • A multi-level perspective on innovation intermediaries : the case of the diffusion of digital technologies in healthcare
  • 2024
  • In: Technovation. - : Elsevier. - 0166-4972 .- 1879-2383. ; 129
  • Journal article (peer-reviewed)abstract
    • Innovation intermediaries have emerged as prominent forms of intervention for supporting technological changes and driving sociotechnical transitions. In this paper, we draw on an in-depth case study tracing the emergence and evolution of an intermediary organization created specifically to address innovation-related challenges and spur digital transformation in the healthcare sector in Montreal, Canada. We analyze data from 85 interviews with leading actors in the healthcare ecosystem, coupled with supplementary material, meetings, and follow-ups to theorize how intermediaries help facilitate the diffusion of emerging digital technologies in this sector. Our analysis reveals two interrelated processes: (1) "technology-focused intermediation" to help co-create the technology in accordance with existing demands; and (2) "ecosystem-focused intermediation" to help reinforce ecosystem components for enabling effective deployment. Each of these processes is driven by sourcing, mobilizing, and scaling activities intended to align the technology development trajectory with envisioned sociotechnical requirements.
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4.
  • Abildgaard, Niels, et al. (author)
  • Real-world treatment patterns and outcomes for patients with multiple myeloma in Denmark, Finland and Sweden : An analysis using linked Nordic registries
  • 2024
  • In: European Journal of Cancer. - : Elsevier. - 0959-8049 .- 1879-0852. ; 201
  • Journal article (peer-reviewed)abstract
    • Aim: The Health outcomes and Understanding of MyelomA multi-National Study (HUMANS) was a large-scale, retrospective study conducted across Denmark, Finland and Sweden using linked data from national registries. We describe the characteristics, treatment patterns and clinical outcomes for patients with newly diagnosed multiple myeloma (NDMM) over 2010–2018.Methods: Patients with NDMM who received MM-specific, first-line treatments, were categorised by treatment (autologous stem cell transplantation [ASCT] or a combination chemotherapy regimen based on bortezomib, lenalidomide or melphalan-prednisolone-thalidomide).Results: 11,023 patients received treatment over 2010–2018. Time between diagnosis and treatment was shortest in Denmark (0.9 months), then Sweden (2.9 months) and Finland (4.6 months). Around one third of patients underwent ASCT. Lenalidomide-based regimens were prescribed to 23–28% of patients in Denmark and Finland, versus 12% in Sweden. Patients receiving lenalidomide had the longest wait for treatment, from 3.2 months (Denmark) to 12.1 months (Sweden). Treatment persistence was highest among patients receiving melphalan-prednisolone-thalidomide (7–8 months) in Finland and Sweden and lowest among those receiving bortezomib (3.5 months) in Finland. Overall survival (OS) was longest among patients with ASCT (7–10 years). Among patients receiving chemotherapy, OS (from diagnosis/treatment initiation), varied between cohorts. In a sensitivity analysis excluding patients with smouldering MM, OS decreased for all; for patients receiving bortezomib or lenalidomide, OS from diagnosis was 40–49 and 27–54 months, respectively.Conclusions: This population-based study of patients with NDMM receiving first-line MM-specific treatment, provides real-world data on treatment patterns and outcomes to complement data from randomised clinical trials.
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5.
  • Abraha Derbew, Atakelti, et al. (author)
  • Assessing the performance of the family folder system for collecting community-based health information in Tigray Region, North Ethiopia : a capture–recapture study
  • 2024
  • In: BMJ Open. - : BMJ Publishing Group Ltd. - 2044-6055. ; 14:2
  • Journal article (peer-reviewed)abstract
    • Objectives: To assess completeness and accuracy of the family folder in terms of capturing community-level health data.Study design: A capture–recapture method was applied in six randomly selected districts of Tigray Region, Ethiopia.Participants: Child health data, abstracted from randomly selected 24 073 family folders from 99 health posts, were compared with similar data recaptured through household survey and routine health information made by these health posts.Primary and secondary outcome measures: Completeness and accuracy of the family folder data; and coverage selected child health indicators, respectively.Results: Demographic data captured by the family folders and household survey were highly concordant, concordance correlation for total population, women 15–49 years age and under 5-year child were 0.97 (95% CI 0.94 to 0.99, p<0.001), 0.73 (95% CI 0.67 to 0.88) and 0.91 (95% CI 0.85 to 0.96), respectively. However, the live births, child health service indicators and child health events were more erratically reported in the three data sources. The concordance correlation among the three sources, for live births and neonatal deaths was 0.094 (95% CI −0.232 to 0.420) and 0.092 (95% CI −0.230 to 0.423) respectively, and for the other parameters were close to 0.Conclusion: The family folder system comprises a promising development. However, operational issues concerning the seamless capture and recording of events and merging community and facility data at the health centre level need improvement.
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6.
  • Adeniyi, Omotayo, et al. (author)
  • Reagentless impedimetric immunosensor for monitoring of methotrexate in human blood serum using multiwalled carbon nanotube@polypyrrole/polytyramine film electrode
  • 2024
  • In: Talanta. - : Elsevier. - 0039-9140 .- 1873-3573. ; 268:Part 1
  • Journal article (peer-reviewed)abstract
    • Ensuring effective monitoring of methotrexate (MTX) levels in the bloodstream of cancer patients undergoing high-dose methotrexate chemotherapy is crucial to prevent potentially harmful side effects. However, the absence of portable analytical devices suitable for point-of-care bedside monitoring has presented a significant obstacle to achieving real-time MTX monitoring. In this study, we developed an impedimetric immunosensor that doesn't require reagents for measuring MTX levels in undiluted human blood serum. This reagentless approach simplifies the assay process, enabling rapid and straightforward MTX quantification. The immunosensor transducer was fabricated by electrodepositing conductive network of porous multiwalled carbon nanotube@polypyrrole/polytyramine on screen-printed gold microchip electrode (SP–Au/MWCNT70@PPy-PTA). Polyclonal anti-MTX antibodies were immobilized on the film, acting as the immunorecognition element. Non-specific binding was prevented by blocking the transducer interface with denatured bovine serum albumin (dBSA) fibrils, resulting in SP-Au/MWCNT70@PPy-PTA/anti-MTXAb|dBSA film electrode. When MTX binds to the SP-Au/MWCNT70@PPy-PTA/anti-MTXAb|dBSA interface, the film conductance and electron transfer resistance changes. This conductivity attenuation allows for electrochemical impedimetric signal transduction without a redox-probe solution. The electrochemical impedance spectroscopy (EIS) results showed increased charge transfer resistance and phase angle as MTX concentrations increased. The SP-Au/MWCNT70@PPy-PTA/anti-MTXAb|dBSA demonstrated high sensitivity, with a linear response from 0.02 to 20.0 μM and a detection limit of 1.93 nM. The detection limit was 50 times lower than the intended safe level of MTX in human serum. The immunosensor exhibited minimal cross-reactivity with endogenous MTX analogs and serum proteins. The SP-Au/MWCNT70@PPy-PTA/anti-MTXAb|dBSA immunosensor presents a simple and rapid method for therapeutic drug monitoring compared to traditional immunoassay systems.
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7.
  • Adewole, Kayode S., et al. (author)
  • Energy disaggregation risk resilience through microaggregation and discrete Fourier transform
  • 2024
  • In: Information Sciences. - : Elsevier. - 0020-0255 .- 1872-6291. ; 662
  • Journal article (peer-reviewed)abstract
    • Progress in the field of Non-Intrusive Load Monitoring (NILM) has been attributed to the rise in the application of artificial intelligence. Nevertheless, the ability of energy disaggregation algorithms to disaggregate different appliance signatures from aggregated smart grid data poses some privacy issues. This paper introduces a new notion of disclosure risk termed energy disaggregation risk. The performance of Sequence-to-Sequence (Seq2Seq) NILM deep learning algorithm along with three activation extraction methods are studied using two publicly available datasets. To understand the extent of disclosure, we study three inference attacks on aggregated data. The results show that Variance Sensitive Thresholding (VST) event detection method outperformed the other two methods in revealing households' lifestyles based on the signature of the appliances. To reduce energy disaggregation risk, we investigate the performance of two privacy-preserving mechanisms based on microaggregation and Discrete Fourier Transform (DFT). Empirically, for the first scenario of inference attack on UK-DALE, VST produces disaggregation risks of 99%, 100%, 89% and 99% for fridge, dish washer, microwave, and kettle respectively. For washing machine, Activation Time Extraction (ATE) method produces a disaggregation risk of 87%. We obtain similar results for other inference attack scenarios and the risk reduces using the two privacy-protection mechanisms.
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8.
  • Adjei, Evans, et al. (author)
  • Charting paths to decolonise economic geography
  • 2024
  • In: Regions. - : Regional Studies Association. - 2167-4582. ; 18
  • Journal article (peer-reviewed)abstract
    • A previous publication advocated for integrating decolonial perspectives as a transversal principle to the practice and progress of economic geography (Morales, 2024). In this paper, we propose tools to achieve this goal, highlighting the opportunities that the expansion and diversification of the subdiscipline presents for doing so, anecdotally, we observe increased representation of women and individuals from diverse backgrounds at major conferences, in graduate schools, and as early career researchers (we are yet to witness such diversification at more advanced career stages). This presents a great opportunity to expand our theorisations, engage with different expertise and backgrounds, and learn from different geographies. However, diversifying the pool of economic geographers is not enough, we need to challenge, revise, and transform the structures, practices, and ideologies that have perpetuated colonial legacies in the areas of theory, curriculum and pedagogy, methodology, and the dissemination of research, in both education and practice. This may be an uncomfortable and lengthy, but necessary task. Here we propose some ideas on how to start.
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9.
  • Adolfsson, Maja (author)
  • Place and youth political action : how place shapes political action in rural Sweden
  • 2024
  • In: Young - Nordic Journal of Youth Research. - : Sage Publications. - 1103-3088 .- 1741-3222. ; 32:2, s. 125-141
  • Journal article (peer-reviewed)abstract
    • There are important gaps in the research on youth political action due to a lack of attention to the roles of place and the experiences of young people in rural places. To address these gaps, this article presents findings from intensive interviews with 15 young people (aged between 16 and 29 years) who identified as politically/socially engaged and lived or had recently lived in a rural place in Sweden. Analysis of their responses, based on constructivist-grounded theory, shows that place dimensions shaped three social processes of young people’s political action: engaging in politics in (rural) places, finding recognition as political actors in (rural) places and negotiating political belonging in relation to (urban) places. By linking these processes with Agnew’s three-dimensional understanding of place, the analysis provides novel insights into how various dimensions of place shape crucial social processes of youth political action.
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10.
  • af Klinteberg, Maja, 1980-, et al. (author)
  • Decreasing prevalence of atopic dermatitis in Swedish schoolchildren : three repeated population-based surveys
  • 2024
  • In: British Journal of Dermatology. - : Oxford University Press. - 0007-0963 .- 1365-2133. ; 190:2, s. 191-198
  • Journal article (peer-reviewed)abstract
    • Background: The prevalence of atopic dermatitis (AD) has increased over several decades and now affects about one-fifth of all children in high-income countries (HICs). While the increase continues in lower-income countries, the prevalence of AD might have reached a plateau in HICs.Objectives: To investigate trends in the prevalence of AD and atopic comorbidity in schoolchildren in Sweden.Methods: The study population consisted of three cohorts of children (median age 8 years) in Norrbotten, Sweden, for 1996 (n = 3430), 2006 (n = 2585) and 2017 (n = 2785). An identical questionnaire that included questions from the International Study of Asthma and Allergies in Childhood (ISAAC) protocol was used in all three cohorts. Trends in AD prevalence were estimated, as well as trends in atopic comorbidity. AD prevalence was estimated both according to the ISAAC definition of AD and by adding the reported diagnosis by a physician (D-AD).Results: The prevalence of AD decreased in the last decade, from 22.8% (1996) and 21.3% (2006) to 16.3% (2017; P < 0.001). The prevalence of D-AD was lower, but the same pattern of decrease was seen, from 9.3% (1996) and 9.4% (2006) to 5.7% (2017; P < 0.001). In all three cohorts, AD was more common among girls than boys (18.9% vs. 13.8% in 2017; P < 0.001). Children from the mountain inlands had a higher prevalence of AD than children from coastal cities (22.0% vs. 15.1% in 2017; P < 0.001). In comparing D-AD, there were no significant differences between the sexes or between inland or coastal living. Concomitant asthma increased over the years from 12.2% (1996) to 15.8% (2006) to 23.0% (2017; P < 0.001). Concomitant allergic rhinitis and allergic sensitization increased from 1996 (15.0% and 27.5%) to 2006 (24.7% and 49.5%) but then levelled off until 2017 (21.0% and 46.7%).Conclusions: The prevalence of AD among schoolchildren in Sweden decreased over the study period, whereas atopic comorbidity among children with AD increased. Although a decrease was seen, AD is still common and the increase in atopic comorbidity among children with AD, especially the increase in asthma, is concerning.
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