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Sökning: WFRF:(Nolte Thomas)

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41.
  • Al-Dulaimy, Auday, et al. (författare)
  • LOOPS : A Holistic Control Approach for Resource Management in Cloud Computing
  • 2021
  • Ingår i: ICPE 2021 - Proceedings of the ACM/SPEC International Conference on Performance Engineering. - New York, NY, USA : Association for Computing Machinery (ACM). - 9781450381949 ; , s. 117-124
  • Konferensbidrag (refereegranskat)abstract
    • In cloud computing model, resource sharing introduces major benefits for improving resource utilization and total cost of ownership, but it can create technical challenges on the running performance. In practice, orchestrators are required to allocate sufficient physical resources to each Virtual Machine (VM) to meet a set of predefined performance goals. To ensure a specific service level objective, the orchestrator needs to be equipped with a dynamic tool for assigning computing resources to each VM, based on the run-Time state of the target environment. To this end, we present LOOPS, a multi-loop control approach, to allocate resources to VMs based on the service level agreement (SLA) requirements and the run-Time conditions. LOOPS is mainly composed of one essential unit to monitor VMs, and three control levels to allocate resources to VMs based on requests from the essential node. A tailor-made controller is proposed with each level to regulate contention among collocated VMs, to reallocate resources if required, and to migrate VMs from one host to another. The three levels work together to meet the required SLA. The experimental results have shown that the proposed approach can meet applications' performance goals by assigning the resources required by cloud-based applications.
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42.
  • Al-Furoukh, Natalie, et al. (författare)
  • ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells
  • 2015
  • Ingår i: Biochimica et Biophysica Acta. Molecular Cell Research. - : Elsevier BV. - 0167-4889 .- 1879-2596. ; 1853:10, s. 2580-2591
  • Tidskriftsartikel (refereegranskat)abstract
    • Proteostasis is crucial for life and maintained by cellular chaperones and proteases. One major mitochondrial protease is the ClpXP complex, which is comprised of a catalytic ClpX subunit and a proteolytic ClpP subunit. Based on two separate observations, we hypothesized that ClpX may play a leading role in the cellular function of ClpXP. Therefore, we analyzed the effect of ClpX overexpression on a myoblast proteome by quantitative proteomics. ClpX overexpression results in the upregulation of markers of the mitochondria( proteostasis pathway, known as the "mitochondrial unfolded protein response" (UPRmt). Although this pathway is described in detail in Caenorhabditis elegans, it is not clear whether it is conserved in mammals. Therefore, we compared features of the classical nematode UPRmt with our mammalian ClpX-triggered UPRmt dataset. We show that they share the same retrograde mitochondria-to-nucleus signaling pathway that involves the key UPRmt transcription factor CHOP (also known as Ddit3, CEBPZ or GADD153). In conclusion, our data confirm the existence of a mammalian UPRmt that has great similarity to the C elegans pathway. Furthermore, our results illustrate that ClpX overexpression is a good and simple model to study the underlying mechanisms of the UPRmt in mammalian cells.
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43.
  • Alhashimi, Anas, et al. (författare)
  • Change-Point and Model Estimation with Heteroskedastic Noise and Unknown Model Structure
  • 2023
  • Ingår i: Int. Conf. Control, Decis. Inf. Technol., CoDIT. - : Institute of Electrical and Electronics Engineers Inc.. - 9798350311402 ; , s. 2126-2132
  • Konferensbidrag (refereegranskat)abstract
    • In this paper, we investigate the problem of modeling time-series as a process generated through (i) switching between several independent sub-models; (ii) where each sub-model has heteroskedastic noise, and (iii) a polynomial bias, describing nonlinear dependency on system input. First, we propose a generic nonlinear and heteroskedastic statistical model for the process. Then, we design Maximum Likelihood (ML) parameters estimation method capable of handling heteroscedasticity and exploiting constraints on model structure. We investigate solving the intractable ML optimization using population-based stochastic numerical methods. We then find possible model change-points that maximize the likelihood without over-fitting measurement noise. Finally, we verify the usefulness of the proposed technique in a practically relevant case study, the execution-time of odometry estimation for a robot operating radar sensor, and evaluate the different proposed procedures using both simulations and field data.
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44.
  • Ashjaei, Mohammad, et al. (författare)
  • A Compact Approach to Clustered Master-Slave Ethernet Networks
  • 2012
  • Ingår i: IEEE International Workshop on Factory Communication Systems - Proceedings, WFCS. - 9781467315739 ; , s. 157-160
  • Konferensbidrag (refereegranskat)abstract
    • Ethernet switches are increasingly used in real-time distributed systems as a technical solution to guarantee the timeliness in communications. However, there are still limitations related to real-time behavior caused by the limited number of priority levels and the possibility of memory overruns with consequent message losses. These limitations can be eliminated using a master/slave technique such as proposed by the FTT paradigm. This led to the FTT-SE protocol that schedules transmissions centrally in a master node. While this protocol has already been well studied and investigated for small networks with a single switch, its extension to larger networks is still an open issue. In this paper we propose a compact clustered solution to scale the FTT-SE protocol to networks of multiple switches by organizing the network in sub-networks composed of one master and one switch each and which can be connected directly, without bridges. This paper also shows how the timeliness of the traffic can still be enforced. The validation is currently on-going.
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45.
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46.
  • Ashjaei, Mohammad, et al. (författare)
  • Dynamic reconfiguration in HaRTES switched ethernet networks
  • 2016
  • Ingår i: IEEE International Workshop on Factory Communication Systems - Proceedings, WFCS. - 9781509023394
  • Konferensbidrag (refereegranskat)abstract
    • The ability of reconfiguring a system during runtime is essential for dynamic real-time applications in which resource usage is traded online for quality of service. The HaRTES switch, which is a modified Ethernet switch, holds this ability for the network resource, and at the same time it provides hard real-time support for both periodic and sporadic traffic. Although the HaRTES switch technologically caters this ability, a protocol to actually perform the dynamic reconfiguration is missing in multi-hop HaRTES networks. In this paper we introduce such a protocol that is compatible with the traffic scheduling method used in the architecture. We prove the correctness of the protocol using a model checking technique. Moreover, we conduct a set of simulation experiments to show the performance of the protocol and we also show that the reconfiguration process is terminated within a bounded time. 
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47.
  • Ashjaei, Mohammad, et al. (författare)
  • Dynamic Reconfiguration in Multi-Hop Switched Ethernet Networks
  • 2014
  • Ingår i: ACM SIGBED Review. Special Issue on 6th Workshop on Adaptive and Reconfigurable Embedded Systems (APRES 2014). - : Association for Computing Machinery (ACM). - 1551-3688. ; 11:3, s. 62-65
  • Tidskriftsartikel (refereegranskat)abstract
    • The FTT-SE protocol provides adaptive real-time communication on Ethernet networks. To assure a continued real-time behavior, FTT-SE integrates admission control with a quality-of-service mechanism, which screen all adaptation and reconfiguration requests, accepting only those that do not compromise the system timeliness. The adaptability and reconfigurability have been deeply studied in the case of single switch FTT-SE architectures, whereas the extension of that for the multi-hop FTT-SE architecture was not yet investigated. Therefore, in this paper we study the challenges of enabling dynamic reconfiguration in multi-hop FTT-SE networks, we propose two methods (one centralized and one distributed) and we present a qualitative comparison between them.
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48.
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49.
  • Ashjaei, Mohammad, et al. (författare)
  • End-to-end Resource Reservations in Distributed Embedded Systems
  • 2016
  • Ingår i: Proceedings - 2016 IEEE 22nd International Conference on Embedded and Real-Time Computing Systems and Applications, RTCSA 2016. ; , s. 1-11
  • Konferensbidrag (refereegranskat)abstract
    • The resource reservation techniques provide effective means to lower the software complexity, ensure predictability and allow flexibility during the development and execution of complex distributed embedded systems. In this paper we propose a new end-to-end resource reservation model for distributed embedded systems. The model is comprehensive in such a way that it supports end-to-end resource reservations on distributed transactions with various activation patterns that are commonly used in industrial control systems. The model allows resource reservations on processors and real-time network protocols. We also present timing analysis for the distributed embedded systems that are developed using the proposed model. The timing analysis computes the end-to-end response times as well as delays such as data age and reaction delays. The presented analysis also supports real-time networks that can autonomously initiate transmissions. Such networks are not supported by the existing analyses. We also include a case study to show the usability of the model and end-to-end timing analysis with resource reservations.
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50.
  • Ashjaei, Mohammad, et al. (författare)
  • Evaluation of dynamic reconfiguration architecture in multi-hop switched ethernet networks
  • 2014
  • Ingår i: 19th IEEE International Conference on Emerging Technologies and Factory Automation, ETFA 2014. - 9781479948468 ; , s. Article number 7005322-
  • Konferensbidrag (refereegranskat)abstract
    • On-the-fly adaptability and reconfigurability are recently becoming an interest in real-time communications. To assure a continued real-time behavior, the admission control with a quality-of-service mechanism is required, that screen all adaptation and reconfiguration requests. In the context of switched Ethernet networks, the FTT-SE protocol provides adaptive real-time communication. Recently, we proposed two methods to perform the online reconfiguration in multi-hop FTT-SE architectures. However, the methods lack the experimental evaluation. In this paper, we evaluate both methods in terms of the reconfiguration time. 
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