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Träfflista för sökning "LAR1:gu ;lar1:(sh);srt2:(1999)"

Search: LAR1:gu > Södertörn University > (1999)

  • Result 1-2 of 2
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1.
  • Elmroth, Kerstin, 1970, et al. (author)
  • Radiation and hypothermia: changes in DNA supercoiling in human diploid fibroblasts
  • 1999
  • In: Anticancer Res. - 0250-7005 .- 1791-7530. ; 19:6B, s. 5307-11
  • Journal article (peer-reviewed)abstract
    • The influence of hypothermia (2 degrees, 15 degrees and 28 degrees C) upon the effect of X-irradiation on chromatin from human diploid fibroblast cells (AG1518) was studied using the fluorescent halo assay. Rewinding of supercoils was inhibited in a dose-dependent manner when cells were irradiated with 4, 8 or 16 Gy. This inhibition of rewinding was reduced when cells were irradiated at subnormal temperatures compared with cells irradiated at 37 degrees C. One hour's preincubation at low temperature did not influence rewinding. When AG1518 cells were irradiated at 37 degrees C in the presence of the radical scavenger DMSO (0.5 M), the radiation-induced damage was reduced. No additional protection of DMSO in hypothermic cells (2 degrees C) was found, possibly indicating that OH-radical-mediated effects are more temperature dependent. These results are similar to those recently found for the malignant MCF-7 cell line.
  •  
2.
  • Petrov, Kristian (author)
  • Tillbaka till glasnost
  • 1999
  • In: Europa. - Göteborg : Humanistiska fakultetsnämnden. - 9173602809 ; , s. 325-337, s. 325-337
  • Book chapter (pop. science, debate, etc.)
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  • Result 1-2 of 2
Type of publication
journal article (1)
book chapter (1)
Type of content
pop. science, debate, etc. (1)
peer-reviewed (1)
Author/Editor
Hultborn, Ragnar, 19 ... (1)
Nygren, Jonas (1)
Petrov, Kristian (1)
Elmroth, Kerstin, 19 ... (1)
Erkell, L. J. (1)
University
University of Gothenburg (2)
Karlstad University (1)
Karolinska Institutet (1)
Language
Swedish (1)
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Medical and Health Sciences (1)
Humanities (1)
Year

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