| 21. |
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| 22. |
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| 23. |
- Dudas, Kerstin, 1963, et al.
(författare)
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Person-centred care inluences the belief in medication in patients with chronic heart failure
- 2013
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Ingår i: European Journal of Heart Failure.. - : Wiley. - 1567-4215 .- 1388-9842 .- 1879-0844. ; 12:Supplement 1
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Purpose: Many patients with chronic heart failure (CHF) seem to fail in adherence to prescribed medication. Confidence in the prescribed medication as well as misconceptions in communication between patient and health care professionals, are well known factors contributing to patients’ adherence. Moreover, patients with CHF have to manage a complex medication treatment and non-adherence seems to be more likely if there is a lack of belief in medication. Person-centered care (PCC) emphasizes partnership between patient and health care professionals including the creation of a common care-plan. Therefore we evaluated if PCC affects patients’ beliefs about prescribed medicines compared to usual care in patients hospitalized for worsening CHF. Methods: Using a controlled before-and-after design, patients hospitalized for worsening CHF were assigned to either a usual care group or a PCC intervention group. Patient-reported belief about their medication was assessed with the Belief about Medication Questionnaire (BMQ). The BMQ consists of three domains: 1) General harm, 2) General overuse, and 3) General Benefit. Results: In total, 248 patients were included in the study; 123 in the usual care group and 125 in the PCC intervention. The PCC group had a significant better score than the usual care group in the BMQ domain General Overuse, mean=9.06 (SD=2.20) vs. mean =9.76, (SD= 4.48) ( p=0.04). There were no differences between the PCC group and the Usual care group in the domain General Harm p=0.70 [mean=12.6 (SD=3.1) vs. mean =12.9 (SD= 3.4)].and General Benefit p=0.31 [mean=16.5 (SD=2.2) vs. mean =16.8 (SD= 2.0]. Conclusion: We found that patients receiving PCC did not belief that medication is overused to the same extent as patients in usual care. These results support our previous findings of less feeling of uncertainty in relation to illness and medication, shorter length of hospital stay and better functional status by applying PCC.
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| 24. |
- Espes, Daniel, 1985-, et al.
(författare)
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Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI
- 2019
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Ingår i: Acta Diabetologica. - : Springer. - 0940-5429 .- 1432-5233. ; 56:10, s. 1113-1120
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Tidskriftsartikel (refereegranskat)abstract
- AIMS: Perfusion of the pancreas and the islets of Langerhans is sensitive to physiological stimuli and is dysregulated in metabolic disease. Pancreatic perfusion can be assessed by both positron emission tomography (PET) and magnetic resonance imaging (MRI), but the methods have not been directly compared or benchmarked against the gold-standard microsphere technique.METHODS: Pigs (n = 4) were examined by [15O]H2O PET and intravoxel incoherent motion (IVIM) MRI technique simultaneously using a hybrid PET/MRI scanner. The pancreatic perfusion was measured both at basal conditions and after intravenous (IV) administration of up to 0.5 g/kg glucose.RESULTS: Pancreatic perfusion increased by 35%, 157%, and 29% after IV 0.5 g/kg glucose compared to during basal conditions, as assessed by [15O]H2O PET, IVIM MRI, and microspheres, respectively. There was a correlation between pancreatic perfusion as assessed by [15O]H2O PET and IVIM MRI (r = 0.81, R2 = 0.65, p < 0.01). The absolute quantification of pancreatic perfusion (ml/min/g) by [15O]H2O PET was within a 15% error of margin of the microsphere technique.CONCLUSION: Pancreatic perfusion by [15O]H2O PET was in agreement with the microsphere technique assessment. The IVIM MRI method has the potential to replace [15O]H2O PET if the pancreatic perfusion is sufficiently large, but not when absolute quantitation is required.
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| 25. |
- Gonsior, M, et al.
(författare)
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Depth-dependent molecular composition and photo-reactivity of dissolved organic matter in a boreal lake under winter and summer conditions
- 2013
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Ingår i: Biogeosciences. - : European Geosciences Union (EGU) / Copernicus Publications. - 1726-4170 .- 1726-4189. ; 10:11, s. 6945-6956
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Tidskriftsartikel (refereegranskat)abstract
- Transformations of dissolved organic matter (DOM) in boreal lakes lead to large greenhouse gas emissions as well as substantial carbon storage in sediments. Using novel molecular characterization approaches and photochemical degradation experiments we studied how seasonal patterns in water column stratification affected the DOM in a Swedish lake under early spring and summer conditions. Dissolved organic carbon (DOC) concentrations were consistently higher above the sediment when compared to surface waters throughout the sampling periods. Photobleaching alone could not explain this difference in DOC because the lake was covered by 40 cm-thick ice during late winter sampling and still showed the same DOC trend. The differences in the molecular diversity between surface DOM in winter and summer were consistent with ongoing photobleaching/ decarboxylation and a possible bacterial consumption of photo-products. Additional photo-degradation experiments using simulated sunlight showed a production of highly oxidized organic molecules and low molecular weight compounds in all late winter samples and also in the deep water sample in summer. In the surface summer DOM sample, few such molecules were produced during the photo-degradation experiments, confirming that DOM was already photobleached prior to the experiments. This study suggests that photobleaching, and therefore also the ice cover during winter, plays a central role in surface DOM transformation, with important differences in the molecular composition of DOM between surface and deep boreal lake waters. The release of DOC from boreal lake sediments also contribute to this pattern. Photochemical degradation of DOM may be more extensive following ice-out and water column turnover when non-light exposed and thereby photosensitive DOM is photo-mineralized. Hence, the yearly DOM photo-mineralization may be greater than inferred from studies of recently light-exposed DOM.
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| 26. |
- Hudecova, Miriam, 1971-, et al.
(författare)
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Endothelial function in patients with polycystic ovary syndrome : a long-term follow-up study
- 2010
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Ingår i: Fertility and Sterility. - : Elsevier BV. - 0015-0282 .- 1556-5653. ; 94:7, s. 2654-2658
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To investigate pulse wave reflection and endothelial-dependent vasodilatation (EDV) in PCOS patients and age-matched healthy controls. Design: Long-term follow-up study. Setting: Department of Women’s and Children’s Health, Uppsala University, Sweden. Patient(s): Sixty-seven PCOS patients with a mean age of 43.3 years at the follow-up investigation and 66 age-matched controls. Intervention: Aplanation tonometry before and after b-2 receptor agonist (terbutaline) challenge. Main outcome measure(s): Baseline augmentation index (AI) aorta, baseline AI-radial, and change in AI-radial following terbutaline administration as a measure of EDV. Result(s): There was no difference in baseline AI-aorta between PCOS patients and control subjects. Change in AI-radial following terbutaline administration was less pronounced in PCOS patients in comparison to control subjects. This difference remained when adjusted for use of combined oral contraceptives/hormone replacement therapy and postmenopausal status but not after adjustment for BMI. Conclusion(s): Middle-aged PCOS patients display signs of endothelial dysfunction in comparison to age-matched controls, but this is largely due to the increased prevalence of independent risk factors for cardiovascular disease found in this group.
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| 27. |
- Jakobsson, Simon, et al.
(författare)
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How does roadside vegetation management affect the diversity of vascular plants and invertebrates? A systematic review
- 2018
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Ingår i: Environmental Evidence. - : Springer Science and Business Media LLC. - 2047-2382. ; 7:1
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Forskningsöversikt (refereegranskat)abstract
- Background: With appropriate management, based on vegetation removal that reverses late-successional vegetation stages, roadsides can support high levels of biodiversity. However, current recommendations for roadside management to conserve or restore biodiversity are largely based on research on non-roadside grassland habitats, and much of the evidence on how roadside management practices affect biodiversity is found in non-peer-reviewed grey literature. Therefore, based on suggestions from key stakeholders and an initial systematic map that identified 97 studies on how biodiversity is affected by vegetation removal on roadsides, we conducted a full systematic review of the effects on plant and invertebrate diversity of disturbance-based maintenance of roadsides. Methods: The review was restricted to effects of non-chemical interventions such as mowing, burning, grazing and mechanical shrub removal. Studies were selected from the systematic map and from an updated search for more recent literature using a priori eligibility criteria. Relevant articles were subject to critical appraisal of clarity and susceptibility to bias, and studies with low or unclear validity were excluded from the review. Data on species richness, species diversity and abundance of functional groups were extracted together with metadata on site properties and other potential effect modifiers. Results from the 54 included studies were summarised in a narrative synthesis, and impacts of mowing practices on the total species richness and diversity of plants and on the abundance of forbs, graminoids and woody plants were quantitatively analysed using t tests of study-level effect ratios. Results: Nearly all of the 54 studies included in the review were conducted in Europe (29) or North America (24). The vast majority of studies (48) examined impacts of mowing. Effects on vascular plants were reported in 51 studies, whereas 8 of the studies reported on invertebrates. Quantitative analysis of plant species richness and species diversity showed that mowing effects were dependent on the interplay between mowing frequency and hay removal. Thus, there were no statistically significant overall effects of mowing vs. no mowing, frequency of mowing, timing of mowing or hay removal. However, species richness was higher in roadsides mowed once or twice per year with hay removal than in unmown roadsides, and positively affected by mowing twice compared to once per year. Similar, but less pronounced, effects were found for plant species diversity. In addition, mowing had a negative impact on woody plant abundance, and increased mowing frequency had a negative impact on graminoid abundance. The few studies on invertebrates showed effects that diverged across taxon groups, and there was not enough data for quantitative analysis of these results. Conclusions: The results provide evidence on the effects of mowing on plant species richness. To increase plant species richness, roadsides should be mowed each year, preferably twice per year, and hay should be removed after each cutting. The review also identifies large knowledge gaps concerning roadside management and its effects on biodiversity, especially regarding invertebrates. Hence, this systematic review provides not only a valuable basis for evidence-based management but also guidance for future research on this topic, essential to inform management of road networks for biodiversity conservation.
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| 28. |
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| 29. |
- Jelkina Albertsson, Galina, et al.
(författare)
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Effect of basicity on chromium partition in CaO-MgO-SiO2-Cr 2O3 synthetic slag at 1873 K
- 2014
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Ingår i: Mineral Processing and Extractive Metallurgy. - 0371-9553 .- 1743-2855. ; 123:2, s. 116-122
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Tidskriftsartikel (refereegranskat)abstract
- The objective of the present work is to get an understanding of the phase relationships in the CaO-MgO-SiO2-Cr2O3 system with a view to control the precipitation of Cr-spinel in the slag phase. The equilibrium phases in CaO-MgO-SiO2-Cr2O3 slag system at 1873 K (1600°C) have been investigated experimentally and compared with the results from thermodynamic calculations. The Cr2O 3 and MgO contents in the slag were fixed at 6 and 8 wt-% respectively. The basicity (CaO/SiO2) of slag was varied in the range 1·0-2·0. A gas/slag equilibrium technique was adopted to synthesise the slag at a high temperature in air. The samples were heated to and soaked at 1873 K (1600°C) for 24 h in order to achieve the equilibrium state and subsequently quenched in water. The chromium distribution and phase compositions in the quenched slag were studied using scanning electron microscope wavelength dispersive spectroscopy and X-ray diffraction techniques. FactSage software was used for the phase equilibrium calculations. The experimental results obtained from the present work were compared with the calculation results from FactSage software. It was found that the spinel formation at 1873 K (1600°C) is favoured in the slag basicity range 1·0-1·4.
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| 30. |
- Lugnet, Johan, et al.
(författare)
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Project: Fuel Efficient Transmission Technology Concepts: Design Methodology
- 2010
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Annan publikation (populärvet., debatt m.m.)abstract
- The need to reduce our consumption of fossil fuels is a major factor influencing governments and industry and decisions being made for future investments. In this vein, Volvo Construction Equipment AB has identified a new transmission technology which has been shown to offer a substantial saving in fuel consumption. The aim of this proposed project is to provide support towards achieving the objective of bringing this new transmission technology to the market as quickly as possible.
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