| 1021. |
- Larsson, Anders, 1977-, et al.
(författare)
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Test-Architecture Optimization and Test Scheduling for SOCs with Core-Level Expansion of Compressed Test Patterns
- 2008
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Ingår i: Design, Automation, and Test in Europe DATE 2008,2008. - Munich, Germany : IEEE Computer Society Press. - 9783981080131 - 9783981080148 ; , s. 188-
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Konferensbidrag (refereegranskat)abstract
- The ever-increasing test data volume for core-based system-on-chip (SOC) integrated circuits is resulting in high test times and excessive tester memory requirements. To reduce both test time and test data volume, we propose a technique for test-architecture optimization and test scheduling that is based on core-level expansion of compressed test patterns. For each wrapped embedded core and its decompressor, we show that the test time does not decrease monotonically with the width of test access mechanism (TAM) at the decompressor input. We optimize the wrapper and decompressor designs for each core, as well as the TAM architecture and the test schedule at the SOC level. Experimental results for SOCs crafted from several industrial cores demonstrate that the proposed method leads to significant reduction in test data volume and test time, especially when compared to a method that does not rely on core-level decompression of patterns.
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| 1022. |
- Larsson, Anders, 1977-
(författare)
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Test Optimization for Core-based System-on-Chip
- 2008
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The semiconductor technology has enabled the fabrication of integrated circuits (ICs), which may include billions of transistors and can contain all necessary electronic circuitry for a complete system, so-called System-on-Chip (SOC). In order to handle design complexity and to meet short time-to-market requirements, it is increasingly common to make use of a modular design approach where an SOC is composed of pre-designed and pre-verified blocks of logic, called cores.Due to imperfections in the fabrication process, each IC must be individually tested. A major problem is that the cost of test is increasing and is becoming a dominating part of the overall manufacturing cost. The cost of test is strongly related to the increasing test-data volumes, which lead to longer test application times and larger tester memory requirement. For ICs designed in a modular fashion, the high test cost can be addressed by adequate test planning, which includes test-architecture design, test scheduling, test-data compression, and test sharing techniques.In this thesis, we analyze and explore several design and optimization problems related to core-based SOC test planning. We perform optimization of test sharing and test-data compression. We explore the impact of test compression techniques on test application time and compression ratio. We make use of analysis to explore the optimization of test sharing and test-data compression in conjunction with test-architecture design and test scheduling. Extensive experiments, based on benchmarks and industrial designs, have been performed to demonstrate the significance of our techniques.
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| 1023. |
- Larsson, Anders, et al.
(författare)
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The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid
- 2015
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Ingår i: Cytokine. - : Elsevier BV. - 1043-4666 .- 1096-0023. ; 76:2, s. 514-518
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Tidskriftsartikel (refereegranskat)abstract
- Cytokines and chemokines regulate many functions in the body including the brain. The interactions between adipose tissue and the central nervous system (CNS) are important for the regulation of energy balance. CNS function is also influenced by age. The aim of the present study was to investigate the effects of body mass index (BMI) and age on cytokine and chemokine levels in cerebrospinal fluid. Cerebrospinal fluid samples (n=89) were collected from patients undergoing routine surgical procedures. The samples were analyzed using the multiplex proximity extension assay (PEA) in which 92 different cytokines are measured simultaneously using minute sample volume. We found no significant correlations between age and cytokine levels for any of the studied markers. In contrast, at a false discovery rate of 10%, 19 markers were significantly associated with BMI (in decreasing significance: FGF-5, ADA, Beta-NGF, CD40, IL-10RB, CCL19, TGF-alpha, SIRT2, TWEAK, SCF, CSF-1, 4E-BP1, DNER, LIF-R, STAMPB, CXCL10, CXCL6, VEGF-A and CX3CL1). This study reveals a clear effect of BMI on cytokine and chemokine levels in cerebrospinal fluid.
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| 1024. |
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| 1025. |
- Larsson, Anders, et al.
(författare)
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The effects of age and gender on plasma levels of 63 cytokines
- 2015
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Ingår i: JIM - Journal of Immunological Methods. - : Elsevier BV. - 0022-1759 .- 1872-7905. ; 425, s. 58-61
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Tidskriftsartikel (refereegranskat)abstract
- Cytokines play important roles as regulators of cell functions, and over the last decades a number of cytokine assays have been developed. The aim of the present study was to investigate the effects of age and gender on a large number of cytokines. Plasma samples were collected from 33 healthy blood donors. The samples were analyzed using the multiplex proximity extension assay (PEA) allowing simultaneous measurement of 92 cytokines and four technical controls. Biomarkers with less than 80% quantitative results were excluded leaving 63 cytokines that were analyzed for the effects of gender and age. The plasma level of three of the investigated biomarkers (DNER, MCP-4 and MMP-10) were found to be significantly different for the two genders (adjusted p-value <0.05), and 15 of the biomarkers (CCL11, CCL25, CDCP1, CSF-1, CXCL11, CXCL9, FGF-23, Flt3L, HGF, IL-10RB, MCP-3, MCP-4, MMP-10, OPG, VEGF-A) were significantly associated with age. This study reveals the effects of age and gender on a large number of cytokine assays. CXCL5 and TNFB were significantly higher in females, while the other markers with significant gender-dependent differences were higher in males. For the markers that were significantly associated with age, only CXCL6 was found to decrease with age, while the other biomarkers increased with age.
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| 1026. |
- Larsson, Anders, et al.
(författare)
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The state of point-of-care testing : a european perspective
- 2015
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Ingår i: Upsala Journal of Medical Sciences. - : Uppsala Medical Society. - 0300-9734 .- 2000-1967. ; 120:1, s. 1-10
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Forskningsöversikt (refereegranskat)abstract
- Abstract Point-of-care testing (POCT) refers to any diagnostic test administered outside the central laboratory at or near the location of the patient. By performing the sample collection and data analysis steps in the same location POCT cuts down on transport and processing delays, resulting in the rapid feedback of test results to medical decision-makers. Over the past decades the availability and use of POCT have steadily increased in Europe and throughout the international community. However, concerns about overall utility and the reliability of benefits to patient care have impeded the growth of POCT in some areas. While there is no agreed-upon standard for how success should be judged, the increases in speed and mobility provided by POCT can lead to substantial advantages over traditional laboratory testing. When properly utilized, POCT has been shown to yield measurable improvements in patient care, workflow efficiency, and even provide significant financial benefits. However, important organizational and quality assurance challenges must be addressed with the implementation of POCT in any health care environment. To ensure maximal benefits it may be necessary to evaluate critically and restructure existing clinical pathways to capitalize better on the rapid test turnaround times provided by POCT.
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| 1027. |
|
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| 1028. |
- Larsson, Anders
(författare)
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Tätare stad lockar mer
- 2011
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Ingår i: Sydsvenska Dagbladet. ; , s. 4-
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Annan publikation (populärvet., debatt m.m.)
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| 1029. |
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| 1030. |
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