| 61. |
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Anatomy of a 21st-century sustainability project: The untold stories
- 2020
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- What does a sustainability project look like in the 21st century? Not the glossy version, but the naked truth? Tired of manicured, over-theorised accounts of the ‘musts’ and ‘shoulds’ of sustainability transitions, we got to the bottom of things; actually, to the very bottom of the project hierarchy: the individual. Our point of departure is that projects are nothing but temporarily interconnected people. This means that if we don’t know what people do and what they think about their work, we will never be able to create a deeper understanding of the project, its rationale and future impact. Making use of the autoethnographic method, this book provides critical insights into what it’s like being part of a 21st-century project. Building on unfiltered first-hand contributions from 73 authors representing the five organs of a project’s anatomy – the brain (theoreticians), the skeleton (leaders), the limbs (strategists), the heart (local stakeholders) and the lungs (researchers) – the book covers all the important aspects of contemporary project-making: (1) projectification as a societal phenomenon; (2) sustainability as the main project buzzword; (3) transdisciplinarity as a hot working method; (4) economy as the invisible project propeller; (5) space as the contextual project qualifier; (6) gender and integration as the obstinate orphans of project-making; (7) trends as the villains of thoughtless project mimicry; (8) politics as the “necessary evil” of projects; and (9) knowledge production as the cornerstone of all project work. The book ends with an extensive critical analysis of what makes a project tick and how to avoid project failure. We infer that talking about project outcomes and impacts is just that… talking. What makes a difference is what can be done to the project in itself. Three important virtues – the ABC of project-making – emanate from this book’s 40 chapters: building good relationships (Affinity), having the guts to make a change (Bravery), and showing willingness to learn (Curiosity). These are the basis for the successful execution of future sustainability projects, where complexity, unpredictability and desperation will become a staple force to recon with. The original contribution of this book is to shed light on the silent triumphs and hidden pathologies of everyday project-making in an effort to elevate individual knowledge to a level of authority for solving the wicked – yet project-infused – problems of our time.
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| 62. |
- Andersen, M. S., et al.
(författare)
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To facilitate a fair bioeconomy transition, stronger regional-level linkages are needed
- 2022
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Ingår i: Biofuels Bioproducts & Biorefining-Biofpr. - : Wiley. - 1932-104X .- 1932-1031. ; 16:4, s. 929-941
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Tidskriftsartikel (refereegranskat)abstract
- The great hopes in Brussels that a circular bioeconomy will help bridge the growing divide between urban and rural areas and allow the hinterlands to prosper from 'green growth' are addressed in this article, which reflects on insights from three Nordic case studies of brown, green and blue biomass use at different levels of technology readiness. A closer examination of the forward, backward, fiscal and final demand linkages at regional level from increased biomass utilization, from eastern Finland and northern Sweden to Jutland and North Atlantic islands, suggests that linkages are and will remain relatively weak, predominantly dashing the expectations. As suppliers and exporters of natural resources, disadvantaged regions may all too easily get locked into a 'staples trap', where the value creation evaporates owing in part to the steep start-up costs and the associated boom-and-bust cycles, which place them in a weak position vis-a-vis the resource manufacturers and consumers. To make the prospects of development, employment and prosperity in the hinterlands materialize, measures are needed to strengthen the regional-level economic linkages. Regional-level revolving funds based on benefit-sharing instruments related to natural resources can be used to bolster economic development, as reflected in such schemes present in both China and Canada. We call for further research into whether and how such approaches can be replicated successfully by channeling revenues from biomass cultivation to regional-scale revolving funds, with mandates to strengthen long-term economic linkages and prosperity within the hinterlands. (c) 2022 The Authors. Biofuels, Bioproducts and Biorefining published by Society of Industrial Chemistry and John Wiley & Sons Ltd
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| 63. |
- Anderson, John B, et al.
(författare)
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Coded Modulation Systems
- 2003
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Ingår i: Kluwer Academic / Plenum Publishers. - 0306472791
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- This textbook studies the 3 main types of coded modulation: trellis-coded modulation (TCM), continuous-phase modulation (CPM) codes, and linear modulation codes like those that arise from filtering and intersymbol interference. In 2 final chapters, code-division multiple-access receivers are discussed. The book begins with a review of coding, modulation and information theory.
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| 64. |
- Anderson, Johan, 1973, et al.
(författare)
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The probability density function tail of the Kardar–Parisi–Zhang equation in the strongly nonlinear regime
- 2016
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Ingår i: Journal of Physics A: Mathematical and Theoretical. - : IOP Publishing. - 1751-8121 .- 1751-8113. ; 49:50, s. 505001-
-
Tidskriftsartikel (refereegranskat)abstract
- An analytical derivation of the probability density function (PDF) tail describing the strongly correlated interface growth governed by the nonlinear Kardar–Parisi–Zhang equation is provided. The PDF tail exactly coincides with a Tracy–Widom distribution i.e. a PDF tail proportional to exp(-cw_2^(3/2)), where w_2 is the the width of the interface. The PDF tail is computed by the instanton method in the strongly non-linear regime within the Martin–Siggia– Rose framework using a careful treatment of the non-linear interactions. Inaddition, the effect of spatial dimensions on the PDF tail scaling is discussed. This gives a novel approach to understand the rightmost PDF tail of the interface width distribution and the analysis suggests that there is no uppercritical dimension.
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| 65. |
- Anderson, Jonathan, 1975, et al.
(författare)
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Thin graphite overlayers: Graphene and alkali metal intercalation
- 2007
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Ingår i: Surface Science. - : Elsevier BV. - 0039-6028. ; 601:4, s. 1167-1175
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Tidskriftsartikel (refereegranskat)abstract
- Using LEED and angle resolved photoemission for characterisation we have prepared graphite overlayers with down to monolayer thickness by heating SiC crystals and monitored alkali metal intercalation for the multilayer films. The valence band structure of the monolayer is similar to that calculated for graphene though downshifted by around 0.8 eV and with a small gap at the zone corner. The shift suggests that the transport properties, which are of much present interest, are similar to that of a biased graphene sample. Upon alkali metal deposition the 3D character of the pi states is lost and the resulting band structure becomes graphene like. A comparison with data obtained for ex situ prepared intercalation compounds indicates that the graphite film has converted to the stage I compounds C8K or CgRb. Advantages with the present preparation method is that the graphite film can be recovered by desorbing small amounts of alkali metal and that the progress of compound formation can be monitored. The energy shifts measured after different deposits indicate that saturation is reached in three steps. Our interpretation is that in the first the alkali atoms are dispersed while the final steps are characterized by the formation of first one and then a second (2 x 2) ordered alkali metal layer adjacent to the uppermost carbon layer. (c) Elsevier B.V. All rights reserved.
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| 66. |
- Andersson, Carl-Henrik, et al.
(författare)
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A Genetic Variant of the Sortilin 1 Gene is Associated with Reduced Risk of Alzheimer's Disease
- 2016
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Ingår i: Journal of Alzheimer's Disease. - 1387-2877 .- 1875-8908. ; 53:4, s. 1353-1363
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Tidskriftsartikel (refereegranskat)abstract
- Alzheimer's disease (AD) is a neurodegenerative disorder represented by the accumulation of intracellular tau protein and extracellular deposits of amyloid-β (Aβ) in the brain. The gene sortilin 1 (SORT1) has previously been associated with cardiovascular disease in gene association studies. It has also been proposed to be involved in AD pathogenesis through facilitating Aβ clearance by binding apoE/Aβ complexes prior to cellular uptake. However, the neuropathological role of SORT1 in AD is not fully understood. To evaluate the associations between gene variants of SORT1 and risk of AD, we performed genetic analyses in a Swedish case-control cohort. Ten single nucleotide polymorphisms (SNPs), covering the whole SORT1 gene, were selected and genotyped in 620 AD patients and 1107 controls. The SNP rs17646665, located in a non-coding region of the SORT1 gene, remained significantly associated with decreased risk of AD after multiple testing (pc = 0.0061). In addition, other SNPs were found to be nominally associated with risk of AD, as well as altered cognitive function and the CSF biomarker Aβ42, but these associations did not survive correction for multiple testing. The fact that SORT1 has been strongly associated with risk of cardiovascular disease is intriguing as cardiovascular disease is also regarded as a risk factor for AD. Finally, increased knowledge about SORT1 function has a potential to increase our understanding of APOE, the strongest risk factor for AD.
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| 67. |
- Andersson, Erik, et al.
(författare)
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Ambio fit for the 2020s
- 2022
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Ingår i: Ambio. - : Springer Nature. - 0044-7447 .- 1654-7209. ; 51:5, s. 1091-1093
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Tidskriftsartikel (refereegranskat)
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| 68. |
- Andersson, Johnn, et al.
(författare)
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The critical role of informed political direction for advancing technology : The case of Swedish marine energy
- 2017
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Ingår i: Energy Policy. - London : Elsevier. - 0301-4215 .- 1873-6777. ; 101, s. 52-64
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Tidskriftsartikel (refereegranskat)abstract
- Marine energy technologies can contribute to meeting sustainability challenges, but they are still immature and dependent on public support. This paper employs the Technological Innovation Systems (TIS) framework to analyze the development and diffusion of Swedish marine energy up until 2014. While there were promising device developers, relevant industrial capabilities, and world-class research, the system suffered from weaknesses in several important innovation processes. Finally, the analysis identifies the lack of informed political direction as a critical blocking factor and highlights its connection to domestic market potential. © 2016 Elsevier Ltd
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| 69. |
- Andersson, Lars-Magnus, 1968, et al.
(författare)
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Lopinavir/ritonavir, atazanavir/ritonavir, and efavirenz in antiretroviral-naïve HIV-1-infected individuals over 144 weeks: An open-label randomized controlled trial.
- 2013
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Ingår i: Scandinavian Journal of Infectious Diseases. - : Informa UK Limited. - 0036-5548 .- 1651-1980. ; 45:7, s. 543-551
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Tidskriftsartikel (refereegranskat)abstract
- Background: The objective of this study was to compare the efficacy of ritonavir boosted atazanavir versus ritonavir boosted lopinavir or efavirenz, all in combination with 2 nucleoside analogue reverse transcriptase inhibitors (NRTIs), over 144 weeks in antiretroviral-naïve HIV-1-infected individuals. Methods: A prospective open-label randomized controlled trial was conducted at 29 sites in Sweden and Norway between April 2004 and December 2009. Patients were randomized to receive either efavirenz 600 mg once daily (EFV), or atazanavir 300 mg and ritonavir 100 mg once daily (AZV/r), or lopinavir 400 mg and ritonavir 100 mg twice daily (LPV/r). The primary endpoints were the proportion of patients with HIV-1 RNA 100,000 copies/ml at baseline had similar response rates in all arms. Conclusion: EFV was superior to LPV/r at week 48, but there were no significant differences between the 3 arms in the long-term (144 weeks) follow-up.
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| 70. |
- Andersson, Martin, 1974, et al.
(författare)
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Vesicle and bilayer formation of diphytanoylphosphatidylcholine (DPhPC) and diphytanoylphosphatidylethanolamine (DPhPE) mixtures and their bilayers' electrical stability
- 2011
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Ingår i: Colloids and Surfaces B: Biointerfaces. - : Elsevier BV. - 0927-7765 .- 1873-4367. ; 82:2, s. 550-561
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Tidskriftsartikel (refereegranskat)abstract
- Lipid bilayers are of interest in applications where a cell membrane mimicking environment is desired. The performance of the lipid bilayer is largely dependent on the physical and chemical properties of the component lipids. Lipid bilayers consisting of phytanoyl lipids have proven to be appropriate choices since they exhibit high mechanical and chemical stability. In addition, such bilayers have high electrical resistances. Two different phytanoyl lipids, 1,2-diphytanoyl-sn-glycero-3-phosphocholine (DPhPC) and 1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine(DPhPE), and various combinations of the two have been investigated with respect to their behavior in aqueous solutions, their interactions with solid surfaces, and their electrical stability. Dynamic light scattering, nuclear magnetic resonance diffusion, and cryogenic transmission electron microscopy measurements showed that pure DPhPC as well as mixtures of DPhPC and DPhPE consisting of greater than 50% (mol%) DPhPC formed unilamellar vesicles. If the total lipid concentration was greater than 0.15 g/l, then the vesicles formed solid-supported bilayers on plasma-treated gold and silica surfaces by the process of spontaneous vesicle adsorption and rupture, as determined by quartz crystal microbalance with dissipation monitoring and atomic force microscopy. The solid-supported bilayers exhibited a high degree of viscoelasticity, probably an effect of relatively high amounts of imbibed water or incomplete vesicle fusion. Lipid compositions consisting of greater than 50% DPhPE formed small flower-like vesicular structures along with discrete liquid crystalline structures, as evidenced by cryogenic transmission electron microscopy. Furthermore, electrophysiology measurements were performed on bilayers using the tip-dip methodology and the bilayers' capacity to retain its electrical resistance towards an applied potential across the bilayer was evaluated as a function of lipid composition. It was shown that the lipid ratio significantly affected the bilayer's electrical stability, with pure DPhPE having the highest stability followed by 3DPhPC:7DPhPE and 7DPhPC:3DPhPE in decreasing order. The bilayer consisting of 5DPhPC:5DPhPE had the lowest stability towards the applied electrical potential.
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