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Träfflista för sökning "WFRF:(Jonsson Anders) srt2:(2000-2004)"

Sökning: WFRF:(Jonsson Anders) > (2000-2004)

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  • Lindmark, Fredrik, et al. (författare)
  • Analysis of the macrophage scavenger receptor 1 gene in Swedish hereditary and sporadic prostate cancer.
  • 2004
  • Ingår i: The Prostate. - : Wiley. - 0270-4137 .- 1097-0045. ; 59:2, s. 132-140
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: The macrophage scavenger receptor 1 (MSR1) gene on chromosome 8p22 was recently reported as a candidate gene for hereditary prostate cancer (HPC). Here, we further elucidate the role of MSR1 in both Swedish families with HPC and in a cohort of unselected prostate cancer. METHODS: DNA samples from 83 Swedish HPC families and 215 unselected population based cases of prostate cancer as well as 425 age-matched controls were genotyped. RESULTS: A total of 18 variants were identified, including 2 exonic, 7 intronic changes, and 9 changes in the 5'- or 3'-uncoding region. Of the two exonic changes, one previously reported truncation mutation was identified, a R293X nonsense mutation. This mutation was found in 2 of the 83 (2.4%) HPC families. The R293X mutation was found more frequently in men with PC (4.9%) than in unaffected men (2.7%), consistent with previous published results, however our results were not significant (P = 0.16). To additionally test for potential association of common sequence variants and increased risk for the disease, five common polymorphisms (PRO3, INDEL1, IVS5-57, P275A, INDEL7) were genotyped in the group of 215 prostate cancer cases and 425 age-matched controls. No association between any of the five common sequence variants and prostate cancer were found. CONCLUSION: Our results suggest that mutations in MSR1 gene might play a role in prostate cancer susceptibility, particularly the R293X mutation. This study warrants further investigations of the role of MSR1 in prostate cancer etiology.
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  • Lindqvist, Per, et al. (författare)
  • Are suicides by jumping off bridges preventable? An analysis of 50 cases from Sweden.
  • 2004
  • Ingår i: Accident; analysis and prevention. - 0001-4575. ; 36:4, s. 691-4
  • Tidskriftsartikel (refereegranskat)abstract
    • This is a community-based sequential case series of 50 individuals who committed suicide by jumping from bridges in two regions of Sweden. Of the 50 subjects, 32 were men and 18 women, with a median age of 35 years. At least 40 had psychiatric problems. The frequency of suicide was highest during the summer months and during the weekends. A total of 27 bridges were used, with a total length of just under 9 km. Three bridges accounted for almost half of all suicides. Limiting the availability of one method of committing suicide is reported to reduce the overall suicide rate; why suicide and injury suicide preventive measures might be considered. Since this study demonstrates that few bridges attract suicide candidates, this injury mechanism needs to be acknowledged by the road system owners and included in the safety work.
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  • Tilliander, Anders, et al. (författare)
  • A mathematical model of the heat transfer and fluid flow in AOD nozzles and its use to study the conditions at the gas/steel interface
  • 2001
  • Ingår i: ISIJ International. - : Iron and Steel Institute of Japan. - 0915-1559 .- 1347-5460. ; 41:10, s. 1156-1164
  • Tidskriftsartikel (refereegranskat)abstract
    • Knowledge of process gas parameters in the area where the gas leaves the nozzle and then enters the molten steel in AOD converters is necessary in order to determine the boundary conditions needed to model the converter process. Using a newly developed mathematical model for an AOD nozzle verified by comparison against laser Doppler anemometer measurements, the objective of this study was to predict characteristics of non-isothermal heat transfer and fluid flow at the nozzle for pure oxygen gas injected into an AOD converter. The inlet boundary conditions for the nozzle simulation were taken from plant data. The investigation showed that the thermodynamic and physical phenomena in the region where the gas enters the steel melt cannot be determined if the transformation of kinetic energy of gas into heat is not considered because this would amount to oversight of the influences of bubble frequency, temperature, etc. on the process. The possible ranges of bubble frequency and temperature for the nozzle conditions in the study were also determined.
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  • Tilliander, Anders, et al. (författare)
  • Effect of Ar/O-2 gas mixtures on heat-transfer and fluid-flow characteristics in AOD nozzles
  • 2000
  • Ingår i: Steel research. - : Wiley. - 0177-4832. ; 71:11, s. 429-434
  • Tidskriftsartikel (refereegranskat)abstract
    • A model of fluid flow and heat transfer in a nozzle used for injection of argon and oxygen in AOD converters was developed earlier. In this study the model was used to determine the effect of changes in the ratio of argon to oxygen in argon-oxygen gas mixtures injected through the nozzle on fluid flow and heat transfer. It was found, for the studied conditions, that the temperature and laminar kinematic viscosity at the nozzle outlet were not dependent on the gas composition. However, the velocity, density, turbulent kinetic energy and dissipation of kinetic energy varied with a change in the fraction of oxygen injected. It is therefore concluded that for use as boundary-condition input data for an AOD converter model (under development), it is important to be able to calculate reliable velocity and turbulence parameter data for gas mixtures of different argon/oxygen ratios.
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  • Allwood, Carl Martin, et al. (författare)
  • Does mood influence the realism of confidence judgments?
  • 2002
  • Ingår i: Scandinavian Journal of Psychology. - : Wiley. - 1467-9450 .- 0036-5564. ; 43:3, s. 253-260
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study we investigated how mood influences the degree of realism in participants’ confidence judgments (based on an episodic memory task). Using music and film in combination, we successfully induced half of the participants into an elated mood, but failed to induce a sad mood in the other half. Contrary to our prediction, our data indicated that there was no difference in the realism of the confidence between the conditions. When relating this result to previous research our conclusion is that there is no, or very little, influence of mood of moderate intensity on the realism of confidence judgments.
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