| 31. |
- Chrcanovic, Bruno, et al.
(författare)
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Dental implants inserted in male versus female patients: a systematic review and meta-analysis.
- 2015
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Ingår i: Journal of oral rehabilitation. - : Wiley. - 1365-2842 .- 0305-182X. ; 42:9
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this meta-analysis was to test the null hypothesis of no difference in the failure rates, marginal bone loss (MBL) and post-operative infection for implants inserted in male or female patients, against the alternative hypothesis of a difference. An electronic search without time or language restrictions was undertaken in December 2014. Eligibility criteria included clinical human studies, either randomized or not. Ninety-one publications were included, with a total of 27 203 implants inserted in men (1185 failures), and 25 154 implants inserted in women (1039 failures). The results suggest that the insertion of dental implants in male patients statistically affected the implant failure rates (RR 1·21, 95% CI 1·07-1·37, P = 0·002). Due to the limited number of studies reporting results on MBL, it is difficult to estimate the real effect of the insertion of implants in different sexes on the marginal bone level. Due to lack of satisfactory information, meta-analysis for the outcome 'post-operative infection' was not performed. The results have to be interpreted with caution due to the presence of several confounding factors in the included studies.
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| 32. |
- Chrcanovic, Bruno, et al.
(författare)
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Factors Influencing Early Dental Implant Failures
- 2016
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Ingår i: Journal of Dental Research. - : SAGE Publications. - 0022-0345 .- 1544-0591. ; 95:9, s. 995-1002
-
Tidskriftsartikel (refereegranskat)abstract
- The purpose of the present study was to assess the influence of local and systemic factors on the occurrence of dental implant failures up to the second-stage surgery (abutment connection). This retrospective study is based on 2,670 patients who received 10,096 implants and were consecutively treated with implant-supported prostheses between 1980 and 2014 at 1 specialist clinic. Several anatomic-, patient-, health-, and implant-related factors were collected. Descriptive statistics were used to describe the patients and implants. Univariate and multivariate logistic regression models were used at the patient level as well as the implant level to evaluate the effect of explanatory variables on the failure of implants up to abutment connection. A generalized estimating equation method was used for the implant-level analysis to account for the fact that repeated observations (several implants) were available for a single patient. Overall, 642 implants (6.36%) failed, of which 176 (1.74%) in 139 patients were lost up to second-stage surgery. The distribution of implants in sites of different bone quantities and qualities was quite similar between implants lost up to and after abutment connection. Smoking and the intake of antidepressants were the statistically significant predictors in the multivariate model (ClinicalTrials. gov NCT02369562).
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| 33. |
- Chrcanovic, Bruno, et al.
(författare)
-
Immediate nonfunctional versus immediate functional loading and dental implant failure rates: A systematic review and meta-analysis
- 2014
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Ingår i: Journal of Dentistry. - : Elsevier BV. - 0300-5712 .- 1879-176X. ; 42:9, s. 1052-1059
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives: The purpose of the present review was to test the null hypothesis of no difference in the implant failure rates, postoperative infection, and marginal bone loss for patients being rehabilitated using dental implants with immediate nonfunctional loading (INFL) compared to immediate functional loading (IFL), against the alternative hypothesis of a difference. Methods: An electronic search without time or language restrictions was undertaken in March 2014. Eligibility criteria included clinical human studies, either randomized or not. The estimates of relative effect were expressed in risk ratio (RR) and mean difference (MD) in millimeters. Results: 1059 studies were identified and 11 studies were included, of which 7 were of high risk of bias, whereas four studies were of low risk of bias. The results showed that the procedure used (nonfunctional vs. functional) did not significantly affect the implant failure rates (P = 0.70), with a RR of 0.87 (95% CI 0.44-1.75). The wide CI demonstrates uncertainty about the effect size. The analysis of postoperative infection was not possible due to lack of data. No apparent significant effects of non-occlusal loading on the marginal bone loss (MD 0.01 mm, 95% CI -0.04-0.06; P = 0.74) were observed. Conclusions: The results of this study suggest that the differences in occlusal loading between INFL and IFL might not affect the survival of these dental implants and that there is no apparent significant effect on the marginal bone loss. Clinical Significance: There has been a controversy concerning whether dental implants should be subjected to immediate functional or nonfunctional loading. As the philosophies of treatment may alter over time, a periodic review of the different concepts is necessary to refine techniques and eliminate unnecessary procedures. This would form a basis for optimum treatment. (C) 2014 Elsevier Ltd. All rights reserved.
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| 34. |
- Chrcanovic, Bruno, et al.
(författare)
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Immediately loaded non-submerged versus delayed loaded submerged dental implants: A meta-analysis.
- 2015
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Ingår i: International Journal of Oral & Maxillofacial Surgery. - : Elsevier BV. - 0901-5027 .- 1399-0020. ; 44:4, s. 493-506
-
Tidskriftsartikel (refereegranskat)abstract
- The purpose of the present meta-analysis was to test the null hypothesis of no difference in the implant failure rate, postoperative infection, and marginal bone loss for patients being rehabilitated with immediately loaded non-submerged dental implants or delayed loaded submerged implants, against the alternative hypothesis of a difference. An electronic search without time or language restrictions was undertaken in March 2014. Eligibility criteria included clinical human studies, either randomized or not. The search strategy resulted in 28 publications. The inverse variance method was used for a random- or fixed-effects model, depending on the heterogeneity. The estimates of an intervention were expressed as the risk ratio (RR) and mean difference (MD) in millimetres. Twenty-three studies were judged to be at high risk of bias, one at moderate risk of bias, and four studies were considered at low risk of bias. The difference between procedures (submerged vs. non-submerged implants) significantly affected the implant failure rate (P=0.02), with a RR of 1.78 (95% confidence interval (CI) 1.12-2.83). There was no apparent significant effect of non-submerged dental implants on the occurrence of postoperative infection (P=0.29; RR 2.13, CI 0.52-8.65) or on marginal bone loss (P=0.77; MD -0.03, 95% CI -0.23 to 0.17).
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| 35. |
- Chrcanovic, Bruno, et al.
(författare)
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Platform switch and dental implants: A meta-analysis.
- 2015
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Ingår i: Journal of dentistry. - : Elsevier BV. - 1879-176X .- 0300-5712. ; 43:6
-
Tidskriftsartikel (refereegranskat)abstract
- To test the null hypothesis of no difference in the implant failure rates, marginal bone loss (MBL) and postoperative infection in patients who received platform-switched implants or platform-matched implants, against the alternative hypothesis of a difference.
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| 36. |
- Duddeck, D. U., et al.
(författare)
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On the Cleanliness of Different Oral Implant Systems: A Pilot Study
- 2019
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Ingår i: Journal of Clinical Medicine. - : MDPI AG. - 2077-0383. ; 8:9
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Tidskriftsartikel (refereegranskat)abstract
- (1) Background: This paper aimed to compare the cleanliness of clinically well-documented implant systems with implants providing very similar designs. The hypothesis was that three well-established implant systems from Dentsply Implants, Straumann, and Nobel Biocare were not only produced with a higher level of surface cleanliness but also provided significantly more comprehensive published clinical documentation than their correspondent look-alike implants from Cumdente, Bioconcept, and Biodenta, which show similar geometry and surface structure. (2) Methods: Implants were analyzed using SEM imaging and energy-dispersive X-ray spectroscopy to determine the elemental composition of potential impurities. A search for clinical trials was carried out in the PubMed database and by reaching out to the corresponding manufacturer. (3) Results: In comparison to their corresponding look-alikes, all implants of the original manufacturers showed-within the scope of this analysis-a surface free of foreign materials and reliable clinical documentation, while the SEM analysis revealed significant impurities on all look-alike implants such as organic residues and unintended metal particles of iron or aluminum. Other than case reports, the look-alike implant manufacturers provided no reports of clinical documentation. (4) Conclusions: In contrast to the original implants of market-leading manufacturers, the analyzed look-alike implants showed significant impurities, underlining the need for periodic reviews of sterile packaged medical devices and their clinical documentation.
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| 37. |
- Duddeck, D. U., et al.
(författare)
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Quality Assessment of Five Randomly Chosen Ceramic Oral Implant Systems: Cleanliness, Surface Topography, and Clinical Documentation
- 2021
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Ingår i: International Journal of Oral & Maxillofacial Implants. - : Quintessence Publishing. - 0882-2786 .- 1942-4434. ; 36:5, s. 863-874
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: After some initial setbacks in the 1970s, ceramic implants seem to be a promising alternative to titanium implants. Since the surface of an implant system represents the interface to surrounding biologic structures, the study focuses on cleanliness and surface topography. Clinical documentation of the corresponding systems completes the picture and allows a better evaluation of zirconia implant systems. Materials and Methods: Five different ceramic implant systems were selected randomly and purchased via blind-shopping: Z5s (Z-Systems), ZiBone (COHO), W implant (TAVDental), ceramic. implant (vitaclinical), and BioWinI/Standard Zirkon Implantat (Champions-Implants/ZV3 system). Three samples of each implant system underwent scanning electron microscopy (SEM) imaging and elemental analysis (EDS). Where appropriate, subsequent Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) was performed to identify the chemical nature of impurities. Surface topography was evaluated, and a search for clinical trials in the PubMed database, on the websites and by written request to each dental implant manufacturer, was performed. Results: Surfaces of Champions implants (ZV3) and Z-Systems implants were relatively clean, whereas the other investigated surfaces of vitaclinical, TAV Dental, and ZiBone implants all displayed organic contaminations on their surfaces. Four of the investigated ceramic implants showed a moderately rough implant surface. Only the vitaclinical ceramic implant had minimal surface roughness. Three ceramic designs-vitaclinical, ZV3, and Z-Systems-had clinical trials documented with up to 3 years of follow-up and results varying between 82.5% and 100% survival. TAV Dental W and ZiBone implant systems lacked properly conducted clinical recording of results. Conclusion: The results of this study showed that it is technically possible to produce zirconia implants that are largely residue-free. On the other hand, the variety of significant residues found in this analysis raises concerns, as contamination may lead to undesirable biologic effects. The lack of clinical studies in peer-reviewed journals does not seem to be relevant for the approval of marketing, nor does the lack of surface cleanliness. In the authors' opinion, a critical analysis of these aspects should be included in a more stringent future analysis prior to the marketing of oral implant systems.
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| 38. |
- Edblad, Thorsten, et al.
(författare)
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Micro-topography of dental enamel and root cementum.
- 2009
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Ingår i: Swedish dental journal. - 0347-9994. ; 33:1, s. 41-8
-
Tidskriftsartikel (refereegranskat)abstract
- The focus for the present study was to characterise dental enamel and cementum at the cervical region of healthy teeth by use of interferometry. The effect of a protein-dissolving enzyme, used for cleaning (Neutrase) on the surface topography, was also evaluated. Knowledge about the normal variation of surface topography of natural teeth is limited. In the design of artificial surfaces, intended to replace the function of lost biological surfaces, detailed knowledge of the latter is therefore of great importance. Nine health caries free premolars were used. The root cementum of three teeth was used for evaluation of Neutrase on the surface. On the six remaining teeth, the differences between the surface textures of enamel and root cementum were evaluated using 3D Interferometry. No statistical significant effect of Neutrase was identified. A significant difference between enamel and root cementum concerning surface topography using the different 3D parameters was recorded. When comparing values from the literature, the topography of artificial materials used in dentistry show similarities with the topography of the enamel and root cementum surfaces evaluated.
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| 39. |
- Eliasson, Alf, 1959, et al.
(författare)
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A retrospective analysis of early and delayed loading of full-arch mandibular prostheses using three different implant systems: clinical results with up to 5 years of loading.
- 2009
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Ingår i: Clinical implant dentistry and related research. - : Wiley. - 1708-8208 .- 1523-0899. ; 11:2, s. 134-48
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Early loading of implant-supported prostheses in the edentulous mandible is widely accepted, but do the clinical results replicate those of delayed loading? PURPOSE: The aim of this study was to evaluate clinical outcome and patient satisfaction with early or delayed loading in patients treated with fixed prostheses, using three different implant systems. MATERIALS AND METHODS: One hundred and nine consecutively treated patients received 490 implants supporting fixed prostheses; 82 patients with Brånemark System implants (Nobel Biocare AB, Göteborg, Sweden), 16 with Astra Tech implants (Astra Tech AB Dental Implant system, Mölndal, Sweden), and 11 with ITI MonoType implants (ITI Dental Implant System, Institute Straumann AG, Waldenburg, Switzerland). Prostheses were placed within 2 to 3 weeks in 55 patients; 54 patients underwent a two-stage procedure. Data were collected from patient records and radiographs; 83 patients attended a clinical examination and received a questionnaire. RESULTS: All patients had fixed prostheses at follow-up with a mean observation time of 3.5 years. Cumulative survival rates (CSRs) were 92.5% of prostheses and 94.4% of implants for early loading, and 98.0 and 97.9% for delayed loading. The mean radiographic bone loss after the first year was small, and at 5 years less than 0.2 mm for both groups. With early loading, significantly more prostheses (p < .05) needed adjustment or replacement. CONCLUSION: Statistically significantly more prostheses needed adjustment or replacement in the early group. The present study suggested lower CSRs for prostheses and implants in the early loading group after 5 years; the difference was not statistically significant. Larger study samples are needed to verify statistically small differences between treatment techniques.
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| 40. |
- Eliasson, Alf, et al.
(författare)
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Fixed partial prostheses supported by 2 or 3 implants: a retrospective study up to 18 years
- 2006
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Ingår i: Int J Oral Maxillofac Implants. ; 21:4, s. 567-74
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: The purpose of this study was to evaluate and compare the long-term performance of fixed partial prostheses supported by 2 or 3 implants. MATERIALS AND METHODS: All patients treated with fixed partial prostheses supported by either 2 or 3 implants during the period 1985 to 1998 were included in this retrospective report. Annual clinical follow-up examinations were performed, with special attention to stability of the prostheses and peri-implant and occlusal conditions. Radiographic examination was performed when the prostheses were delivered (year 0) and subsequently at 1-year, 5-year, and 10-year examinations. RESULTS: A total of 178 patients had received fixed partial prostheses (FPPs) during this period of whom 123 (77 women and 46 men) were available for follow-up (mean age = 65 years, range 32-91). These 123 patients received a total of 146 implant-supported FPPs (63 two-implant- and 83 three-implant-supported) supported by 375 implants. The mean observation periods for the 2- and 3-implant-supported restorations were 9.6 years and 9.4 years (range, 5 to 18 years), respectively. Survival rates for the 2- and 3-implant-supported prostheses were 96.8% and 97.6%, respectively. The implant survival rate after loading was 98.4% for both groups. The mean bone loss at the 5-year follow-up was 0.3 mm for the 2 groups. No significant differences in bone loss (P > .05), implant failure rate (P > .05), or incidence of mechanical complications (P > .05) were found between the 2 prosthesis designs. The complications differed, significantly, with more loose gold and abutment screws in the 2-implant-supported group (P < .05) and more porcelain fractures in the 3-implant-supported group (P < .05). CONCLUSION: The 2-implant-supported partial prostheses exhibited long-term clinical performance comparable to prostheses supported by 3 implants.
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