| 21. |
- Erós, N, et al.
(författare)
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[New aspects in the classification of cutaneous lymphomas]. : Szemléletváltozás a kután lymphomák klasszifikációjában.
- 2001
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Ingår i: Orvosi hetilap. - 0030-6002. ; 142:8, s. 393-8
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Tidskriftsartikel (refereegranskat)abstract
- Authors discuss the classification of primary cutaneous lymphomas created by the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer (EORTC) in 1996, which is based on the clinical, histological, immunohistochemical and genetic features of cutaneous lymphomas. Unlike the previous histologic classifications it contains well-defined disease entities characterized by their clinical and histological picture, clinical outcome, behaviour and therapeutic response. This classification does not use the term of low grade or high grade lymphoma, but introduces the indolent, aggressive and provisional subgroups in the T-cell lymphomas, and indolent, intermediate and provisional subgroups in the B-cell group. Authors demonstrate the EORTC classification by their own cases calling the attention to the clinical and therapeutic difference between nodal and extranodal lymphomas, and discuss the up-to-date therapeutic possibilities.
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| 22. |
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| 23. |
- Éva, Hadházi, et al.
(författare)
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Elozetes eredmények egy magyar mintán kidolgozott Intrauterin Kapcsolati Kérdoív méréses tapasztalatairól-pilot study
- 2017
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Ingår i: Mentalhigiene es Pszichoszomatika. - : Akademiai Kiado Zrt.. - 1419-8126 .- 1786-3759. ; 18:3, s. 263-300
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Tidskriftsartikel (refereegranskat)abstract
- Background: The effects of "maternal environment" on fetal development have been studied since the eighties, but the results regarding the features which influence mother-fetus relationship are inconsistent. Aim: To develop a mother-fetus relationship assessment scale on a Hungarian sample, and to reveal the factors that determine mother-fetus bonding. Method: 114 pregnant women, between 15 and 38 weeks of gestational age, filled out the Intrauterine Relationship Questionnaire, the Hungarian version of Maternal Fetal Attachment Scale, Intimate Bond Measurement and Parental Bonding Instrument. Results: our 28 items Intrauterine Relationship Questionnaire's (IURQ) factor structure indicators proved to remain below the expectations (RMSEA =. 08, χ 2/df = 1.645, NFI =. 85, CFI =. 87). The eight subscales' Cronbach's alphas are between. 56 and. 93. With exploratory factor analysis we managed to develop a shortened version model (IURQ-S), with better psychometric characteristics, which contains 12 items and 3 subscales (RMSEA =. 08, χ 2/df = 1.660, NFI =. 95, CFI =. 96). The internal consistency of IURQ-S is high, Cronbach's alphas range from. 81 to. 93. For further analyses we used the IURQ-S model. Our questionnaire correlate with MFAS-HU but their dimensions are not entirely overlapping. In accordance with international experiences we found that a mother reaches significantly higher scores on the mother-fetus relationship scale, if she can be characterized with any of the following: married, has high contribution to family income, no previous experience of miscarriage, born in natural way, without any intervention, definitely knows or definitely does not know the fetus' sex. The time of the pregnancy had no substantial effect, neither had the educational background of the mother or whether the pregnancy was planned. The method of conception, the number of children born previously and the fetal movement did not prove to be decisive either. Fetal attachment correlated with partnership intimacy: higher mother-fetus attachment scores were found with higher perceived care and lower perceived control. The mother's own parental bonding, her perceived maternal and paternal love was found to be in positive correlation with her attachment to her fetus. Conclusions: The questionnaire reliability is promising, but further validity examinations are needed in a larger, more heterogeneous sample. The results have drawn our attention to the importance of parental bonding and perceived partner care during pregnancy, and can help prevention of early attachment disfunction.
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| 24. |
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| 25. |
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| 26. |
- Farkas, Zita
(författare)
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Az abortusz szigorítása, mint nemzeti emnacipáció
- 2012
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Ingår i: Társadalmi Nemek Tudománya: Interdiszciplináris eFolyóirat . [Interdisciplinary eJournal of Gender Studies]. - 2062-7084. ; 2:2, s. 113-131
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Tidskriftsartikel (refereegranskat)
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| 27. |
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| 28. |
- Frida, Katona, et al.
(författare)
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A melanoma és az agyi áttétképzödés molekuláris háttere
- 2017
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Ingår i: Orvosi Hetilap. - : Akademiai Kiado Zrt.. - 0030-6002 .- 1788-6120. ; 158:28, s. 1083-1091
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Forskningsöversikt (refereegranskat)abstract
- Malignant melanoma is one of the most aggressive tumors which often gives metastasis to distant organs thereby limiting the chances of survival. Brain metastasis occurs in nearly half of the advanced tumors. In order to improve outcome early diagnosis is important. The discovery and better understanding of genetic and epigenetic changes is essential for developing new effective therapies, which can designate promising therapeutic targets. Melanoma most often is caused by gene mutations of the mitogen-activated protein kinase pathway, the phosphatidylinositol 3-kinase signaling pathway, and the cell cycle regulatory molecules, respectively. The molecular process of brain metastasis has not been fully elucidated. In our review we summarize the genetic alterations and molecular mechanisms playing a role in the development of melanoma and its brain metastasis.
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| 29. |
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| 30. |
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