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Träfflista för sökning "WFRF:(Isaxon Christina) ;pers:(Oudin Anna)"

Sökning: WFRF:(Isaxon Christina) > Oudin Anna

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2.
  • Flanagan, Erin, et al. (författare)
  • Air Pollution and Urban Green Space : Evidence of Environmental Injustice in Adama, Ethiopia
  • 2021
  • Ingår i: Frontiers in Sustainable Cities. - : Frontiers Media SA. - 2624-9634. ; 3
  • Tidskriftsartikel (refereegranskat)abstract
    • While air pollution data in Ethiopia is limited, existing studies indicate high levels of both ambient and household air pollution; rapid urbanization also threatens the preservation of urban green spaces. In this study, environmental injustice, or the disproportionate burden of environmental exposures on persons of lower socioeconomic status (SES), was explored among women in Ethiopia using a mother and child cohort from the city of Adama. Land-use regression models were previously developed for modeling ambient nitrogen dioxide (NO2) and nitrogen oxides (NOx) throughout Adama, while household air pollution (cooking fuel type) and the presence of green space were assessed through questionnaires and home visits, respectively. The odds of being exposed to these environmental factors were analyzed in association with two SES indicators, education and occupation, using logistic regression. Our results indicate the presence of environmental injustice in Adama, as women with lower SES shouldered a higher burden of air pollution exposure and enjoyed less urban green space than their higher SES counterparts. These findings encourage the prioritization of air quality control and urban planning resources toward policy action within lower SES areas. From a societal perspective, our results also support more upstream interventions, including investment in educational and occupational opportunities. Still, a human rights approach is emphasized, as governments are responsible for protecting the right to a clean environment, especially for those disproportionately exposed. To the best of our knowledge, this is the first study on environmental injustice in Ethiopia, and the first in Sub-Saharan Africa to investigate the inequalities of ambient and household air pollution exposure as well as urban green space access in the same cohort.
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3.
  • Flanagan, Erin, et al. (författare)
  • Ambient and indoor air pollution exposure and adverse birth outcomes in Adama, Ethiopia
  • 2022
  • Ingår i: Environment International. - : Elsevier BV. - 0160-4120. ; 164
  • Tidskriftsartikel (refereegranskat)abstract
    • Air pollution poses a threat to human health, with pregnant women and their developing fetuses being particularly vulnerable. A high dual burden of ambient and indoor air pollution exposure has been identified in Ethiopia, but studies investigating their effects on adverse birth outcomes are currently lacking. This study explores the association between ambient air pollution (NOX and NO2) and indoor air pollution (cooking fuel type) and fetal and neonatal death in Adama, Ethiopia. A prospective cohort of mothers and their babies was used, into which pregnant women were recruited at their first antenatal visit (n = 2085) from November 2015 to February 2018. Previously developed land-use regression models were utilized to assess ambient concentrations of NOX and NO2 at the residential address, whereas data on cooking fuel type was derived from questionnaires. Birth outcome data was obtained from self-reported questionnaire responses during the participant's postnatal visit or by phone if an in-person meeting was not possible. Binary logistic regression was employed to assess associations within the final study population (n = 1616) using both univariate and multivariate models; the latter of which adjusted for age, education, parity, and HIV status. Odds ratios (OR) and their corresponding 95% confidence intervals (CI) were reported. Within the cohort, 69 instances of fetal death (n = 16 miscarriages; n = 53 stillbirths) and 16 cases of neonatal death were identified. The findings suggest a tendency towards an association between ambient NOX and NO2 exposure during pregnancy and an increased risk of fetal death overall as well as stillbirth, specifically. However, statistical significance was not observed. Results for indoor air pollution and neonatal death were inconclusive. As limited evidence on the effects of exposure to ambient air pollution on adverse birth outcomes exists in Sub-Saharan Africa and Ethiopia, additional studies with larger study populations should be conducted.
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  • Mandakh, Yumjirmaa, et al. (författare)
  • Association of prenatal ambient air pollution exposure with placental mitochondrial DNA copy number, telomere length and preeclampsia
  • 2021
  • Ingår i: Frontiers in Toxicology. - : Frontiers Media S.A.. - 2673-3080. ; 3
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damage. Objective: To study the association between prenatal exposure to ambient nitrogen oxides (NOx, a marker for traffic-related air pollution), and PE, as well as potential mediation effects by placental telomere length and mtDNAcn.Methods: This is a cross-sectional study of 42 preeclamptic and 95 arbitrarily selected normotensive pregnant women with gestational ambient NOx exposure assessment in southern Scania, Sweden. Hourly concentrations of NOx were estimated at the residential addresses by a Gaussian-plume dispersion model with 100 × 100 m spatial resolutions and aggregated into trimester-specific mean concentrations. Placental relative mtDNAcn and telomere length were measured using qPCR. Linear and logistic regression models were used to investigate associations, adjusted for perinatal and seasonal characteristics.Results: Exposure was categorized into low and high exposures by median cut-offs during first [11.9 μg/m3; interquartile range (IQR) 7.9, 17.9], second (11.6 μg/m3; IQR: 7.1, 21.1), third trimesters (11.9 μg/m3; IQR: 7.7, 19.5) and entire pregnancy (12.0 μg/m3; IQR: 7.6, 20.1). Increased risk of PE was found for high prenatal NOx exposure during the first trimester (OR 4.0; 95% CI: 1.4, 11.1; p = 0.008), and entire pregnancy (OR 3.7; 95% CI: 1.3, 10.4; p = 0.012). High exposed group during the first trimester had lower placental relative mtDNAcn compared with low exposed group (−0.20; 95% CI: −0.36, −0.04; p = 0.01). Changes in relative mtDNAcn did not mediate the association between prenatal NOx exposure and PE. No statistically significant association was found between placental relative telomere length, prenatal NOx exposure and PE.Conclusion: In this region with relatively low levels of air pollution, ambient NOx exposure during the first trimester was associated with reduced placental relative mtDNAcn and an increased risk of PE. However, we did not find any evidence that mtDNAcn or TL mediated the association between air pollution and PE. Future research should further investigate the role of mtDNAcn for pregnancy complications in relation to exposure to ambient air pollution during pregnancy.
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6.
  • Mandakh, Yumjirmaa, et al. (författare)
  • Maternal Exposure to Ambient Air Pollution and Risk of Preeclampsia : A Population-Based Cohort Study in Scania, Sweden
  • 2020
  • Ingår i: International Journal of Environmental Research and Public Health. - : MDPI AG. - 1660-4601. ; 17:5
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to investigate the risk of developing preeclampsia (PE) associated with gestational exposure to ambient air pollutants in southern Sweden, a low-exposure area. We used a cohort of 43,688 singleton pregnancies and monthly mean exposure levels of black carbon (BC), local and total particulate matter (PM2.5 and PM10), and NOX at the maternal residential address estimated by Gaussian dispersion modeling from 2000 to 2009. Analyses were conducted using binary logistic regression. A subtype analysis for small-for-gestational age (SGA) was performed. All analyses were adjusted for obstetrical risk factors and socioeconomic predictors. There were 1286 (2.9%) PE cases in the analysis. An adjusted odds ratio (AOR) of 1.35 with a 95% confidence interval (CI) of 1.11-1.63 was found when comparing the lowest quartile of BC exposure to the highest quartile in the third trimester The AOR for PE associated with each 5 µg/m3 increase in locally emitted PM2.5 was 2.74 (95% CI: 1.68, 4.47) in the entire pregnancy. Similar patterns were observed for each 5 µg/m3 increment in locally emitted PM10. In pregnancies complicated by PE with SGA, the corresponding AOR for linear increases in BC was 3.48 (95% CI: 1.67, 7.27). In this low-level setting, maternal exposure to ambient air pollution during gestation was associated with the risk of developing PE. The associations seemed more pronounced in pregnancies with SGA complications, a finding that should be investigated further.
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7.
  • Stroh, Emilie, et al. (författare)
  • Luftföroreningshalter på förskolegårdar
  • 2021
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • På uppdrag av Naturvårdsverket har avdelningen för Arbets- och miljömedicin vid Lunds Universitet utfört studie kring luftföroreningssituationen på förskolegårdar.  Denna studie består av tre delar vara av en är en kunskapsinventering bland landetskommuner kring luftkvalitén på förskolebarns utemiljöer och effekter/strategier för att eventuellt förbättra detta. (sedan tidigare publicerad i denna rapportserie (nr 10:2019). Utöver detta har det även genomförts mätningar av NO2 samt PM10 och PM2,5 på de tio mest luftförorenings drabbade förskolorna i Malmö. Dessa mätningar pågick mellan hösten 2018 till våren 2020 och låg till grund för del tre i studien där de uppmätta halternas hälsokonsekvenser hos barn beräknades.  Studien visar att flertalet kommuner saknar aktuell mätdata kring hur luftförorenings situationen ser ut i kommunen och mycket få har kännedom om luftkvalitén i anslutning till kommunens förskolor.  Mätningarna vid förskolorna i Malmö visar att partikelhalterna på förskolegårdarna i dessa trafikutsatta miljöer överskrider miljömålen men också att den kraftiga minskning av trafiken i Malmö som skedde i samband med Covid-19 restriktionerna hade en positiv effekt med en kraftig minskning av uppmätta halter. Något  som  även återspeglas  hälsokonsekvens beräkningarna.
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