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Träfflista för sökning "WFRF:(Olsson K) srt2:(1971-1974)"

Sökning: WFRF:(Olsson K) > (1971-1974)

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  • Kristensson, K, et al. (författare)
  • Distribution of protein tracers in the nervous system of the crayfish (Astacus astacus L) following systemic and local application
  • 1972
  • Ingår i: Journal of Neurocytology. - 0300-4864. ; 1, s. 35-48
  • Tidskriftsartikel (refereegranskat)abstract
    • A study was made on the penetration and cellular uptake of two protein tracers, albumin labelled with Evans blue (EBA) and horseradish peroxidase (HP), in the nervous system of the crayfish following systemic and local administration. Followingsystemic injection, EBA did not diffuse freely from the cerebral vessels into the brain parenchyma. When the tracers werelocally applied on the surface of the ventral nerve cord their penetration into the nervous parenchyma was to some extent restricted by the nerve sheath. However, unlike the perineurium of vertebrate peripheral nerves, which acts as an efficient diffusion barrier, the crayfish nerve sheath allowed the diffusion of small amounts of tracers into the ganglia. The tracers could more readily penetrate into peripheral nerves in the vicinity of ganglia. Inside the ganglion the tracers spread in extracellular spaces, between glial cell membranes and reached the neuronal surfaces. The proteins were taken up by pinocytosis in glial cells, and also in axons.
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