| 1. |
-
2-(p-Hydroxybenzyl)indoles - Side Products Formed Upon Cleavage of Indole Derivatives from Carboxylated Wang Polymer - an NMR Study.
- 2003
-
Ingår i: molecules. ; 8:10, s. 728-734
-
Tidskriftsartikel (refereegranskat)abstract
- Treatment of carboxylated Wang polymer attached to a 2-unsubstituted indole derivative with a trifluoroacetic acid based mixture resulted in a side reaction: p-hydroxybenzylation at the 2-position of the indole ring. The structure of the resulting N-3- aminopropyl)-N-benzyl-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]-butyramide trifluoroacetate was ascertained by a full assignment of its 1H- and 13C-NMR spectra. The side reaction could be suppressed by the use of 1,2-ethanedithiol in high concentrations (16 %).
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
- A. Nojima,, et al.
(författare)
-
Calculational aspects of electron-phonon coupling at surfaces
- 2008
-
Ingår i: J. Phys: Condens. Matter. - : IOP Publishing. - 1361-648X .- 0953-8984. ; 20
-
Tidskriftsartikel (refereegranskat)abstract
- We study the validity of two frequently used approximations in calculations of electron–phonon coupling at surfaces. The rigid-ion approximation is a standard approximation used for the bulk metals. On the basis of density functional theory calculations, we find that for Be this approximation is as valid for surface atoms as for bulk atoms. In addition, the slab method for calculations of a phonon induced surface state lifetime is examined. The convergence of the electron–phonon matrix element with respect to the thickness of the slab is studied for several systems. When the number of slab layers is increased, the net effect of decreasing overlap and increasing number of final states depends strongly on the decay length of the surface state wavefunction and the band structure.
|
|
| 6. |
- A. Nojima,, et al.
(författare)
-
Model Eliashberg function for surface states
- 2008
-
Ingår i: Applied Surface Science. ; 254:23
-
Tidskriftsartikel (refereegranskat)abstract
- We present a simplified procedure for the analysis of the phonon-induced lifetimes of surface states. The model includes information about the electron and phonon structure and is thus more reliable than procedures based on phonon Debye models. We apply the model to calculate the lifetime broadening of Cu(1 1 1) and Al(0 0 1) surface states. The obtained Eliashberg functions and lifetimes are in reasonable agreement with previous detailed studies.
|
|
| 7. |
- Aaberge, Rolf, et al.
(författare)
-
Evaluation of an In-work Tax Credit Reform in Sweden: Effects on Labor Supply and Welfare Participation of Single Mothers
- 2008
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The purpose of this paper is to evaluate a recent Swedish in-work tax credit reform where we pay particular attention to labor market exclusion; i.e. individuals in as well as outside the labor force are included in the analysis. To highlight the importance of the joint effects from the tax and the benefit systems it appears particular relevant to analyze the labor supply behavior of single mothers. To this end, we estimate a structural microeconometric model of labor supply and welfare participation. The model accounts for heterogeneity in consumption-leisure preferences as well as for constraints in job opportunities. The results of the evaluation show that the reform generates welfare-gains for virtually every single mother, and moreover benefits low-income households. Finally, due to increased labor supply and decline in welfare participation we find that this reform is almost self-financing.
|
|
| 8. |
- Aalto-Setälä, Katriina, et al.
(författare)
-
Genetic risk factors and ischemic cerebrovascular disease : role of common variation of the genes encoding apolipoproteins and angiotensin-converting enzyme
- 1998
-
Ingår i: Annals of Medicine. - 0785-3890 .- 1365-2060. ; 30:2, s. 224-33
-
Tidskriftsartikel (refereegranskat)abstract
- DNA polymorphisms in genes encoding apolipoproteins (apo) A-I, C-III, B and E and angiotensin-converting enzyme (ACE) have been proposed to be associated with the risk of coronary artery disease (CAD). We studied whether the same genetic markers would also be associated with the occurrence and extent of atherosclerosis in cervical arteries. DNA samples from 234 survivors of stroke or a transient ischaemic attack aged 60 years or less were examined. The presence of atherosclerosis was assessed using aortic arch angiograms. The SstI polymorphism of apoA-I/C-III gene locus, the XbaI polymorphism of apoB gene, common apoE phenotypes and the insertion/deletion polymorphism of the ACE gene were analysed. The allele frequencies of the apoA-I/C-III, apoB, apoE or ACE gene did not differ between the groups with (n = 148) or without (n = 85) cervical atherosclerosis. However, when patients with at least one apoE4 allele and one X2 allele of apoB were combined and compared with those without either of them (E2E3 or E3E3 and X1X1), a significant association with the presence of cervical atherosclerosis was found (P = 0.03). The patients having the E2E3 phenotype had a significantly elevated serum triglyceride level compared with those with the E3E3 phenotype (P = 0.03). Serum high-density lipoprotein (HDL) cholesterol was lower in the patients with the E2E3 phenotype than in those with the E3E3 and E3E4 (P = 0.01 and P = 0.06, respectively). The apoB or ACE genotypes were not significantly associated with serum lipid or lipoprotein levels. There was no association between the ACE gene polymorphism and the occurrence of hypertension. In conclusion, the interaction of common apoB and apoE alleles may increase the risk of atherosclerosis in cervical arteries.
|
|
| 9. |
- Aaro Jonsson, Catherine C., et al.
(författare)
-
Variability in quality of life 13 years after traumatic brain injury in childhood
- 2014
-
Ingår i: International Journal of Rehabilitation Research. - : Wolters Kluwer. - 0342-5282 .- 1473-5660. ; 37:4, s. 317-322
-
Tidskriftsartikel (refereegranskat)abstract
- With the aim of describing variability in the long-term outcome of quality of life after neurosurgically treated pediatric traumatic brain injury, mostly self-reports of 21 individuals with mild or moderate/severe injury were gathered using Mayo-Portland Adaptability Inventory in telephone interviews 13 years aftyer injury. A majority of the participants reported brain injury-related problems. The median outcome on Mayo-Portland Adaptability Inventory was mild to moderate limitations. The variation within the moderate/severe group varied between relatively good outcome and moderate/severe limitations. Concentration, irritability, fatigue, and transportation were reported as the most problematic areas, whereas self-care was reported as well functioning. Societal participation appeared to be the best functional domain in this Swedish study. Examples of individual reports of the life-situation at various outcome levels were provided. Variability in outcome is large within severity groups, and research may gain by addressing both outcomes of the individuals and groups. Objective questions of outcome should be accompanied by questions of actual functioning in everyday life. To ensure long-term support for quality of life for those with remaining dysfunction after pediatric traumatic brain injury, healthcare systems should implement systematic routines for referral to rehabilitation and support.
|
|
| 10. |
- Aaro Jonsson, Catherine, 1963-, et al.
(författare)
-
Long-term cognitive outcome after neurosurgically treated childhood traumatic brain injury
- 2009
-
Ingår i: Brain Injury. - : Taylor & Francis. - 0269-9052 .- 1362-301X. ; 23:13-14, s. 1008-1016
-
Tidskriftsartikel (refereegranskat)abstract
- Objective: To explore the cognitive long term outcome of two cohorts of patients neurosurgically treated for childhood traumatic brain injury (CTBI), either in 1987-1991 according to an older concept, or 1997-2001 with a stronger emphasis on volume targeted interventions. Research design and methods: Participants in the two cohorts were subject to an extensive neuropsychological assessment, 13.2 and 6.1 years post injury, respectively. In a between group design, assessment results of the two cohorts, n 18 and n 23, were compared to each other and to controls. Data were analyzed with multivariate analyses of variance. Results: Long-term cognitive deficits for both groups of similar magnitude and character were observed in both groups. Abilities were especially low regarding executive and memory function and verbal IQ. The cognitive results are discussed in terms of vulnerability of verbal functions and decreased executive control over memory-functions. Conclusions: There is a definite need for long term follow up of cognitive deficits after neurosurgically treated CTBI, also with the newer neurosurgical concept. Verbal learning and the executive control over memory functions should be addressed with interventions aimed at restoration, coping and compensation.
|
|
