| 1. |
- Airiskallio, E., et al.
(författare)
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Third element effect in the surface zone of Fe-Cr-Al alloys
- 2010
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Ingår i: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 81:3
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Tidskriftsartikel (refereegranskat)abstract
- The third element effect to improve the high temperature corrosion resistance of the low-Al Fe-Cr-Al alloys is suggested to involve a mechanism that boosts the recovering of the Al concentration to the required level in the Al-depleted zone beneath the oxide layer. We propose that the key factor in this mechanism is the coexistent Cr depletion that helps to maintain a sufficient Al content in the depleted zone. Several previous experiments related to our study support that conditions for such a mechanism to be functional prevail in real oxidation processes of Fe-Cr-Al alloys.
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| 2. |
- Baltanas, R., et al.
(författare)
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Pheromone-Induced Morphogenesis Improves Osmoadaptation Capacity by Activating the HOG MAPK Pathway
- 2013
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Ingår i: Science Signaling. - : American Association for the Advancement of Science (AAAS). - 1937-9145 .- 1945-0877. ; 6:272
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Tidskriftsartikel (refereegranskat)abstract
- Environmental and internal conditions expose cells to a multiplicity of stimuli whose consequences are difficult to predict. We investigate the response to mating pheromone of yeast cells adapted to high osmolarity. Events downstream of pheromone binding involve two mitogen-activated protein kinase (MAPK) cascades: the pheromone response (PR) and the cell wall integrity (CWI) response. Although the PR MAPK pathway shares components with a third MAPK pathway, the high osmolarity (HOG) response, each one is normally only activated by its cognate stimulus, a phenomenon called insulation. We found that in cells adapted to high osmolarity, PR activated the HOG pathway in a pheromone- and osmolarity-dependent manner. Activation of HOG by the PR was not due to loss of insulation, but rather a response to a reduction in internal osmolarity, which resulted from an increase in glycerol release caused by the PR. By analyzing single-cell time courses, we found that stimulation of HOG occurred in discrete bursts that coincided with the "shmooing" morphogenetic process. Activation required the polarisome, the CWI MAPK Slt2, and the aquaglyceroporin Fps1. HOG activation resulted in high glycerol turnover, which improved adaptability to rapid changes in osmolarity. Our work shows how a differentiation signal can recruit a second, unrelated sensory pathway to fine-tune yeast response in a complex environment.
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| 3. |
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| 4. |
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| 5. |
- Fonsati, Arianna, et al.
(författare)
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From Geotechnical Data to GeoBIM Models : Testing Strategies for an Ex-Industrial Site in Turin
- 2023
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Ingår i: Buildings. - : MDPI AG. - 2075-5309. ; 13:9
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Tidskriftsartikel (refereegranskat)abstract
- Over the years, the use of Building Information Modelling (BIM) methods has changed the workflows of various actors, providing better integration across different domains and allowing for new ways of working. This paper outlines the interest towards the integration of BIM with geotechnical/geological modelling (GeoBIM), which still represents a major challenge in several respects. The present study aims to provide a flexible method for assessing various integration strategies and to establish a preferred workflow based on the selected requirements and preference parameters. This integration is designed to provide a final federated model that can also be archived in the as-built documentation. Four alternative processes were selected to analyse the specific types of data and transformations required in the process. Each process was applied on a real case study in order to test the developed assessment framework using the Analytical Hierarchy Process (AHP). Due to technological advances, modelling and integration workflows change rapidly; however, our results show that the proposed evaluation framework is universal and adaptable to any new integration approach. Further research efforts must be undertaken to reduce attribute data losses and enhance the interoperability between systems and professionals.
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| 6. |
- Herlitz, Johan
(författare)
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Överlevnad efter hjärtstopp på sjukhus
- 2001
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Ingår i: Akuttjournalen. - : BioMed Central Ltd.. - 0805-6129 .- 1500-7480. ; 98, s. 152-157
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Tidskriftsartikel (refereegranskat)
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| 7. |
- Hogberg, G., et al.
(författare)
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Mood Regulation Focused CBT Based on Memory Reconsolidation, Reduced Suicidal Ideation and Depression in Youth in a Randomised Controlled Study
- 2018
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Ingår i: Int J Environ Res Public Health. - : MDPI AG. - 1660-4601. ; 15:5
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Tidskriftsartikel (refereegranskat)abstract
- Suicide attempts and suicidal ideation in adolescence are considered to be related to suicide and psychiatric adversity later in life. Secondary prevention by improving the treatment of suicidal youth is a distinct possibility. In this study, treatment with a systematised mood-regulation focused cognitive behavioural therapy (MR-CBT) (n = 15) was compared with treatment as usual (TAU) (n = 12) in a group of depressed adolescents in a clinical setting. MR-CBT focuses on mood regulation by means of counter conditioning with memory reconsolidation being the proposed mechanism of change. Subjects practice keeping emotionally positive memories to diminish the emotional impact of negative memories. Symptoms of depression were tested with a short version of the Mood and Feelings Questionnaire (SMFQ), and wellbeing with the World Health Organization 5 Wellbeing Index (WHO-5). Suicidal events were rated according to the clinical interview Columbia Suicide Severity Rating Scale (C-SSRS). Suicidal events at the end of treatment were significantly reduced in the MR-CBT group, but not in the TAU group. Depression and wellbeing improved significantly in both treatment groups. While far from conclusive, the results are encouraging enough to suggest that further studies should be undertaken to examine whether psychotherapy focusing on mood regulation for young individuals at risk might enhance secondary prevention of suicide.
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| 8. |
- Huang, Huaiqi, et al.
(författare)
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Multi-modal sensory feedback system for upper limb amputees
- 2017
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Ingår i: Proceedings - 2017 1st New Generation of CAS, NGCAS 2017. - 9781509064472 ; , s. 193-196
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Konferensbidrag (refereegranskat)abstract
- Providing sensory feedback for myoelectric prosthetic users can not only increase the manipulation ability but can also introduce a feeling of embodiment. Previous research has demonstrated the feasibility of providing mechanotactile or vibrotactile feedback on the remaining stumps of amputees. To improve the recognition rate and reduce mental work load when identifying stimulation patterns, we propose a multi-modal sensory feedback system for upper limb amputees. The system consists of five tactile sensors, Bluetooth wireless communication modules, and a custom-designed multi-modal stimulation array incorporating vibrotactile and mechanotactile stimulation modalities. Three amputees (two with phantom map and one without phantom map) tested the system in localization and stimulation intensity identification tasks. Experimental results show the effectiveness of the multi-modal stimulation compared with single modal stimulation. To the best of our knowledge, this is the first attempt to combine vibrotactile and mechanotactile stimulation in a sensory feedback system for upper limb amputees.
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| 9. |
- Hugelius, Karin, 1977-, et al.
(författare)
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"We Thought We Were Prepared, but We Were Not" : Experiences from the Management of the Psychosocial Support Response during the COVID-19 Pandemic in Sweden. A Mixed-Methods Study
- 2021
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Ingår i: International Journal of Environmental Research and Public Health. - : MDPI. - 1661-7827 .- 1660-4601. ; 18:17
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Tidskriftsartikel (refereegranskat)abstract
- This study aimed to describe experiences of managing mental health and psychosocial activities during the first six months of the COVID-19 pandemic in Sweden. A national survey was answered by a non-probability sample of 340 involved in the psychosocial response. The psychosocial response operations met several challenges, mainly related to the diverse actors involved, lack of competence, and lack of preparations. Less than 20% of the participants had received specific training in the provision of psychosocial support during major incidents. The interventions used varied, and no large-scale interventions were used. The psychosocial response organizations were overwhelmed by the needs of health care staff and failed to meet the needs of patients and family members. An efficient and durable psychosocial response in a long-term crisis requires to be structured, planned and well-integrated into the overall pandemic response. All personnel involved need adequate and specific competence in evidence-based individual and large-scale interventions to provide psychosocial support in significant incidents. By increasing general awareness of mental wellbeing and psychosocial support amongst health professionals and their first-line managers, a more resilient health care system, both in everyday life and during major incidents and disasters, could be facilitated.
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| 10. |
- Jakobsson, Ulf, et al.
(författare)
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Old people in pain: A comparative study.
- 2003
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Ingår i: Journal of Pain and Symptom Management. - 1873-6513. ; 26:1, s. 625-636
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Tidskriftsartikel (refereegranskat)abstract
- To investigate the prevalence of pain in older people (75+), compare those in pain to those without regarding demographics, social network, functional limitations, fatigue, sleeping problems, depressed mood and quality of life (QOL), and identify variables associated with pain, a cross-sectional, prospective survey was conducted in an age-stratified sample of 4,093 people aged 75–105 years old. Those reporting pain (n = 1,654) were compared with those who did not (n = 2,439). Pain was more common with higher age, as were all complaints among those in pain and among those without, except sleeping problems. Lower QOL was found with higher age, as well as with pain. Pain was found to be associated with functional limitations, fatigue, sleeping problems, depressed mood, and QOL. These data highlight the importance of identifying old people in pain. Those who are older and those affected by pain are at greater risk of also being troubled by other problems, such as functional limitations and lowered QOL.
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