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Sökning: WAKA:kon > Högskolan i Borås > Lindecrantz Kaj

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21.
  • Seoane, Fernando, 1976-, et al. (författare)
  • Brain electrical impedance at various frequencies : the effect of hypoxia
  • 2004
  • Ingår i: Proceedings of the 26th Annual International Conference of the IEEE EMBS, San Francisco, CA, USA • September 1-5, 2004. - : IEEE Engineering in Medicine and Biology Society. - 0780384393 ; 3, s. 2322-5
  • Konferensbidrag (refereegranskat)abstract
    • Non-invasive multi-frequency measurements of transcephalic impedance, both reactance and resistance, can efficiently detect cell swelling of brain tissue and can be used for early detection of threatening brain damage. We have performed experiments on piglets to monitor transcephalic impedance during hypoxia. The obtained results have confirmed the hypothesis that changes in the size of cells modify the tissue impedance. During tissue inflammation after induced hypoxia, cerebral tissue exhibits changes in both reactance and resistance. Those changes are remarkably high, up to 71% over the baseline, and easy to measure especially at certain frequencies. A better understanding of the electrical behaviour of cerebral tissue during cell swelling would lead us to develop effective non-invasive clinical tools and methods for early diagnosis of cerebral edema and brain damage prevention.
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22.
  • Seoane, Fernando, 1976-, et al. (författare)
  • Current Source for Wideband Electrical Bioimpedance Spectroscopy Based on a Single Operational Amplifier
  • 2006
  • Ingår i: WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2006, VOL 14, PTS 1-6. - : IFMBE. - 9783540368397 ; , s. 707-710
  • Konferensbidrag (refereegranskat)abstract
    • Traditionally, measurements of electrical bioimpedance for medical diagnostic purposes have used only low frequencies, usually below 100 kHz. The analysis focused only on the resistive part of the impedance; very often at low frequencies the reactive part of the impedance is negligible. Recent studies of the electrical bioimpedance spectrum, both real and imaginary parts, have indicated new potential applications e.g. detection of meningitis, skin cancer assessment and brain cellular edema detection. An important functional unit in a wideband impedance spectrometer is the current source used to inject the current into the tissue under study. A current source must provide an output current virtually constant over the frequency range of interest and independent of the load at the output. Several designs have been proposed over the years but the performance of them all degraded markedly near bellow 1 MHz e.g. Ackmann in 1993, Bragos et al in 1994 and Bertemes-Filho et al in 2000. The development of electronic technology has made available devices that allow us to obtain a current source with large output impedance, larger than 100 k Omega, above I MHz and based in a simple single Op-Amp circuit topology. Simulation results and experimental measurements are compared and the most important parameters of the VCCS are analytically studied and experimentally tested, including the dependency to changes in the circuit elements and the incidence of the Op-Amp parameters on the current source features.
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23.
  • Seoane, Fernando, et al. (författare)
  • Textile-enabled Instrumentation for Impedance Cardiographic Signals
  • 2011
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • Research efforts in the areas of Electrical Bioimpedance (EBI) and textile materials with conductive properties have contributed to the proliferation of research projects aiming to test the feasibility of implementing Textile-enabled instrumentation for performing EBI measurements. Most of the work done has been focused on the electrical characterization of the Textrodes (textile electrodes) and on spectroscopy applications of EBI like early detection of Cardiogenic Pulmonary Edema. In this work, a garment composed of two belts containing Textrodes made of conductive Velcro, loops-type, has been manufactured. Both, the abdomen and the neck belts, have four Textrodes connected through a conductive fabric Technik Tex P-130+ Shieldex fabric in pairs. This way, a tetrapolar EBI measurement between the neck and the chest is performed, implementing a typical band electrode arrangement [1] approach with the two belts. Using a custom-made device Respimon that measures the electrical cardiac activity with a 1-lead ECG and a tetrapolar EBI measurement at 50kHz of a portion of the body, and the Textrode garment, the ICG and ECG signals have been recorded and compared with the recordings obtained with Ag/AgCl electrodes placed in the same positions. The resemblance of the ICG and ECG signals obtained with both the Ag/AgCl electrodes and the Textrode garment confirms the feasibility of using Textrodes to perform measurements of cardiac impedance. There are several useful hemodynamic parameters that can be extracted from the ICG signal in combination with the ECG signal. The availability of a Textrode garment, easy to wear and that produces reliable ICG measurements, would contribute to present ICG monitoring as feasible technology for implementing personalized healthcare monitoring systems, especially for e-health applications of heart failure patients management.
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